Diagnostic Value of 3.0T MRI in Cartilage Injury Grading of Knee Osteoarthritis

doi:10.1166/jmihi.2020.3247

HFCAS OpenIR

	Diagnostic Value of 3.0T MRI in Cartilage Injury Grading of Knee Osteoarthritis
	Zhang, Xiaoming 1,2,3; Tong, Haiyang1 ; Zhang, Jin1 ; Xu, Jinyong 3; Xia, Shiyong 4
	2020-12-01
发表期刊	JOURNAL OF MEDICAL IMAGING AND HEALTH INFORMATICS
ISSN	2156-7018
通讯作者	Xia, Shiyong()
摘要	Objective: At present, the grading diagnosis of knee osteoarthritis is mostly subjective evaluation, and lack of quantitative criteria, which brings some difficulty to diagnosis. To solve this problem, this study selected easily quantifiable indicators, such as cartilage thickness, cartilage volume and signal value, and analyzes their application value in grading diagnosis of cartilage injury by observing their change characteristics under MRI. Methods: Clinical data were collected from 54 patients with osteoarthritis of the knee (KOA) and 12 healthy volunteers, including 27 males and 39 females; age 38-63 years, with an average age of 47 +/- 6.9 years. A total of 110 knee joints were tested, including 86 affected and 24 healthy joints. MRI data were collected, including patella, medial and lateral femoral condyle, medial and lateral tibial condyle, and for grading. The results were compared with those of arthroscopy to analyze the consistency of the two diagnostic methods. The 110 knee joints were divided into 5 groups according to the arthroscopic grading (0-IV grade), and compare the differences of cartilage thickness, cartilage volume and signal value under MRI among groups. Result: Among them, in terms of MRI grading, there were 15 cases of I grade, 21 cases of II grade, 26 cases of III grade, and 24 cases of IV grade. In terms of arthroscopy grading, there were 16 cases of I grade, 23 cases of II grade, 25 cases of III grade, and 22 cases of IV grade. The kappa value of the two diagnostic methods was 0.91, with high consistency (P < 0.01). According to the results of arthroscopic grading diagnosis and analysis of the corresponding MRI data, it was found that the average thickness of normal articular cartilage in the patella, lateral tibia condyle, medial tibia condyle, lateral femur condyle, medial femur condyle is gradually thinning, and the thickness of articular cartilage in each part gradually thinned with the increase of injury grade. The difference between I grade and 0 grade was not statistically significant, and except for that, among other groups there were statistically significant (P 0.01); The volume of normal articular cartilage decreased from medial femoral condyle, lateral femoral condyle, patella, lateral tibial condyle and medial tibial condyle in turn, and the volume decreased gradually with the increase of injury grade. Except for the difference between I grade and 0 grade, there were statistical significance between other groups (P <0.01); signal value of normal articular cartilage decreased from medial tibial condyle, lateral femur condyle, medial femur condyle, lateral tibial condyle and patella in turn. Signal value increased with the increase of injury grade. Except for the difference between III grade and IV grade, there were statistical significance between other groups (P < 0.01). Conclusion: MRI grading of cartilage injury in knee osteoarthritis is highly consistent with arthroscopy, with high accuracy. In MRI grading, reference to cartilage thickness, cartilage volume and signal value can effectively improve the diagnosis rate.
关键词	Osteoarthritis Knee Magnetic Resonance Imaging Arthroscopy Thickness of the Cartilage Cartilage Volume Signal Value
DOI	10.1166/jmihi.2020.3247
关键词[WOS]	ARTICULAR-CARTILAGE ; JOINT SPACE
收录类别	SCI
语种	英语
WOS研究方向	Mathematical & Computational Biology ; Radiology, Nuclear Medicine & Medical Imaging
WOS类目	Mathematical & Computational Biology ; Radiology, Nuclear Medicine & Medical Imaging
WOS记录号	WOS:000565930500030
出版者	AMER SCIENTIFIC PUBLISHERS
引用统计	被引频次：1[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.hfcas.ac.cn:8080/handle/334002/104061
专题	中国科学院合肥物质科学研究院
通讯作者	Xia, Shiyong
作者单位	1.Chinese Acad Sci, Hefei Inst Phys Sci, High Magnet Field Lab, Hefei 230031, Peoples R China 2.Univ Sci & Technol China, Hefei 230026, Peoples R China 3.Anhui Med Univ, Dept Anat, Hefei 230032, Peoples R China 4.First Peoples Hosp Hefei, Hefei Binhu Hosp, Magnet Resonance Imaging Room, Hefei 230061, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Xiaoming,Tong, Haiyang,Zhang, Jin,et al. Diagnostic Value of 3.0T MRI in Cartilage Injury Grading of Knee Osteoarthritis[J]. JOURNAL OF MEDICAL IMAGING AND HEALTH INFORMATICS,2020,10.
APA	Zhang, Xiaoming,Tong, Haiyang,Zhang, Jin,Xu, Jinyong,&Xia, Shiyong.(2020).Diagnostic Value of 3.0T MRI in Cartilage Injury Grading of Knee Osteoarthritis.JOURNAL OF MEDICAL IMAGING AND HEALTH INFORMATICS,10.
MLA	Zhang, Xiaoming,et al."Diagnostic Value of 3.0T MRI in Cartilage Injury Grading of Knee Osteoarthritis".JOURNAL OF MEDICAL IMAGING AND HEALTH INFORMATICS 10(2020).