Role of Hydrogen Bonding in Green Fluorescent Protein-like Chromophore Emission

HFCAS OpenIR

	Role of Hydrogen Bonding in Green Fluorescent Protein-like Chromophore Emission
其他题名	Role of Hydrogen Bonding in Green Fluorescent Protein-like Chromophore Emission
	Yang, Li 1; Nian, Shifeng 3; Zhang, Guozhen 3; Sharman, Edward 4; Miao, Hui 3; Zhang, Xuepeng 3; Chen, Xiaofeng 5; Luo, Yi 3; Jiang, Jun 3
	2019
发表期刊	SCIENTIFIC REPORTS
ISSN	2045-2322
摘要	The fluorescence emission from green fluorescent protein (GFP) is known to be heavily influenced by hydrogen bonding between the core fluorophore and the surrounding side chains or water molecules. Yet how to utilize this feature for modulating the fluorescence of GFP chromophore or GFP-like fluorophore still remains elusive. Here we present theoretical calculations to predict how hydrogen bonding could influence the excited states of the GFP-like fluorophores. These studies provide both a new perspective for understanding the photophysical properties of GFP as well as a solid basis for the rational design of GFP-based fluorophores.
其他摘要	The fluorescence emission from green fluorescent protein (GFP) is known to be heavily influenced by hydrogen bonding between the core fluorophore and the surrounding side chains or water molecules. Yet how to utilize this feature for modulating the fluorescence of GFP chromophore or GFP-like fluorophore still remains elusive. Here we present theoretical calculations to predict how hydrogen bonding could influence the excited states of the GFP-like fluorophores. These studies provide both a new perspective for understanding the photophysical properties of GFP as well as a solid basis for the rational design of GFP-based fluorophores.
语种	英语
资助项目	[973 Program] ; [NSFC]
文献类型	期刊论文
条目标识符	http://ir.hfcas.ac.cn:8080/handle/334002/124167
专题	中国科学院合肥物质科学研究院
作者单位	1.Hefei Institutes of Physical Science, Chinese Academy of Sciences 2.Anhui University 3.University of Science & Technology of China, CAS 4.University of California System 5.Shanghai Normal University
推荐引用方式 GB/T 7714	Yang, Li,Nian, Shifeng,Zhang, Guozhen,et al. Role of Hydrogen Bonding in Green Fluorescent Protein-like Chromophore Emission[J]. SCIENTIFIC REPORTS,2019,9.
APA	Yang, Li.,Nian, Shifeng.,Zhang, Guozhen.,Sharman, Edward.,Miao, Hui.,...&Jiang, Jun.(2019).Role of Hydrogen Bonding in Green Fluorescent Protein-like Chromophore Emission.SCIENTIFIC REPORTS,9.
MLA	Yang, Li,et al."Role of Hydrogen Bonding in Green Fluorescent Protein-like Chromophore Emission".SCIENTIFIC REPORTS 9(2019).