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Perioperative change in neutrophil count predicts worse survival in esophageal squamous cell carcinoma
Song, Qian1,2; Wu, Junzhou2,3; Wang, Sheng1,2; Xu, Songxiao1,2
2021-08-25
发表期刊FUTURE ONCOLOGY
ISSN1479-6694
通讯作者Xu, Songxiao(xusx@zjcc.org.cn)
摘要Aims: This study aimed to investigate the relationship between perioperative change in neutrophil count and survival of patients with esophageal squamous cell carcinoma. Method: Neutrophil change (Nc) (where Nc = post-surgery neutrophil count - pre-surgery neutrophil count) was counted according to data within 1 week before surgery and 2 weeks after surgery. Patients were divided into two groups, Nc >= 2.60 and Nc <2.60, according to the median of Nc. Results: Multivariate analysis revealed that Nc >= 2.60 was an independent prognostic marker for overall survival. Subgroup analysis suggested that the overall survival of male patients, patients aged <= 60 years, patients without vessel invasion and patients without nerve infiltration was dramatically worse for those with Nc Conclusion: Perioperative change in neutrophil count predicts worse survival in esophageal squamous cell carcinoma after surgery.
关键词esophageal squamous cell carcinoma neutrophil perioperative change prognosis survival
DOI10.2217/fon-2021-0371
关键词[WOS]CIRCULATING TUMOR-CELLS ; PROGNOSTIC-FACTOR ; LYMPHOCYTE RATIO ; T-CELLS ; PROMOTE ; CANCER ; MICROENVIRONMENT ; METASTASIS ; EXPRESSION ; RISK
收录类别SCI
语种英语
资助项目National Natural Science Foundation of China[81602615] ; Zhejiang Youth Talents Project[2019RC026] ; General research program of Health Department of Zhejiang Province[2020KY480] ; Natural Science Foundation of Zhejiang Province[LQ21H200001]
项目资助者National Natural Science Foundation of China ; Zhejiang Youth Talents Project ; General research program of Health Department of Zhejiang Province ; Natural Science Foundation of Zhejiang Province
WOS研究方向Oncology
WOS类目Oncology
WOS记录号WOS:000688122200001
出版者FUTURE MEDICINE LTD
引用统计
被引频次:2[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.hfcas.ac.cn:8080/handle/334002/125180
专题中国科学院合肥物质科学研究院
通讯作者Xu, Songxiao
作者单位1.Univ Chinese Acad Sci, Canc Hosp, Zhejiang Canc Hosp, Dept Clin Lab, Hangzhou 310022, Zhejiang, Peoples R China
2.Chinese Acad Sci, Inst Basic Med & Canc IBMC, Hangzhou 310022, Zhejiang, Peoples R China
3.Univ Chinese Acad Sci, Canc Hosp, Canc Res Inst, Zhejiang Canc Hosp, Hangzhou 310022, Zhejiang, Peoples R China
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Song, Qian,Wu, Junzhou,Wang, Sheng,et al. Perioperative change in neutrophil count predicts worse survival in esophageal squamous cell carcinoma[J]. FUTURE ONCOLOGY,2021.
APA Song, Qian,Wu, Junzhou,Wang, Sheng,&Xu, Songxiao.(2021).Perioperative change in neutrophil count predicts worse survival in esophageal squamous cell carcinoma.FUTURE ONCOLOGY.
MLA Song, Qian,et al."Perioperative change in neutrophil count predicts worse survival in esophageal squamous cell carcinoma".FUTURE ONCOLOGY (2021).
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