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A Scientometric Visualization Analysis for Natural Products on Cancer Research from 2008 to 2020
Chen, Haitao1; Li, Rongrong2; Zhang, Fan1; Yao, Qinghua3; Guo, Yong4
2021-08-06
发表期刊FRONTIERS IN PHARMACOLOGY
通讯作者Yao, Qinghua(yaoqh@zjcc.org.cn) ; Guo, Yong(guoyong1047@zcmu.edu.cn)
摘要Background: An increasing number of studies have shown that natural products have anti-tumor effects, and it has become a hotspot in cancer research. However, few bibliometric analyses have been examined in this field systematically. The current study aimed to explore the status and provide the developing trends in the natural products on cancer research. Methods: Publications on natural products in cancer research were extracted from the Web of Science core collection database. CiteSpace (5.6.R3) software and GraphPad prism 6 were used to analyze and plot the references. Results: On February 1, 2021, 34,611 records of natural products in cancer research published from 2008 to 2020 were collected. The United States was the driving force, with a strong academic reputation in this area. The top-contributing institution was the Chinese Academy of Sciences. Most publications were published in Molecules. Efferth Thomas was the most prolific author, while Newman DJ was the most cited and frequently co-cited author. Flavonoid, curcumin, and polyphenol were the most widely studied natural products. Oleanolic acid and rosmarinic acid have gradually become research hotspots recently. Breast cancer, prostate cancer, and colorectal cancer were the most common types of cancer in this field. "Natural killer cell" was the leading research hotspot. The keywords of "leaf extract," "molecular docking" and "gold nanoparticle" appeared most recently as research frontiers. Conclusion: Our results provided a general overview of the major research directions of natural products research in cancer. The mechanisms of natural products, especially those related to molecular docking, gold nanoparticle, gut microbiota, and immune checkpoints may soon become hotspots and should be closely monitored.
关键词natural product cancer bibliometric citation analysis molecular docking gut microbiota immune checkpoint
DOI10.3389/fphar.2021.650141
关键词[WOS]CHEMOTHERAPY ; MODULATION ; INDUCTION ; APOPTOSIS ; AUTOPHAGY ; CELLS ; ACID
收录类别SCI
语种英语
WOS研究方向Pharmacology & Pharmacy
WOS类目Pharmacology & Pharmacy
WOS记录号WOS:000693420100001
出版者FRONTIERS MEDIA SA
引用统计
被引频次:8[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.hfcas.ac.cn:8080/handle/334002/125278
专题中国科学院合肥物质科学研究院
通讯作者Yao, Qinghua; Guo, Yong
作者单位1.Zhejiang Chinese Med Univ, Clin Coll 1, Hangzhou, Peoples R China
2.Zhejiang Chinese Med Univ, Clin Coll 3, Hangzhou, Peoples R China
3.Univ Chinese Acad Sci, Dept Integrated Tradit Chinese & Western Med, Canc Hosp, Zhejiang Canc Hosp, Hangzhou, Peoples R China
4.Zhejiang Chinese Med Univ, Dept Oncol, Affiliated Hosp 1, Hangzhou, Peoples R China
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GB/T 7714
Chen, Haitao,Li, Rongrong,Zhang, Fan,et al. A Scientometric Visualization Analysis for Natural Products on Cancer Research from 2008 to 2020[J]. FRONTIERS IN PHARMACOLOGY,2021,12.
APA Chen, Haitao,Li, Rongrong,Zhang, Fan,Yao, Qinghua,&Guo, Yong.(2021).A Scientometric Visualization Analysis for Natural Products on Cancer Research from 2008 to 2020.FRONTIERS IN PHARMACOLOGY,12.
MLA Chen, Haitao,et al."A Scientometric Visualization Analysis for Natural Products on Cancer Research from 2008 to 2020".FRONTIERS IN PHARMACOLOGY 12(2021).
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