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Simultaneous extraction and surface enhanced Raman spectroscopy detection for the rapid and reliable identification of nicotine released from snus products
Tian, Yongfeng1; Tang, Xianghu2,3; Fu, Yaning4; Shang, Shanzhai1; Dong, Gaofeng1; Li, Tinghua1; Huang, Xingjiu2,3; Zhu, Donglai1
2021-12-02
Source PublicationANALYTICAL METHODS
ISSN1759-9660
Corresponding AuthorTang, Xianghu(tangxh2011@iim.ac.cn) ; Zhu, Donglai(zhudl@ynzy-tobacco.com)
AbstractSurface enhanced Raman spectroscopy (SERS) is a highly sensitive analytical detection technique that provides unique chemical and structural information on target molecules. Here, simultaneous extraction and SERS detection of nicotine for the rapid and reliable identification of nicotine released from snus products were performed based on a nano-Au assembly hierarchy structure in the capillary. Based on this strategy, the time evolution of the concentrations of nicotine released from the snus products was measured. Through comparison of the intensities of the spectral peaks of the symmetrical breathing of the pyridine moiety of nicotine molecules, with the prolongation of time, the concentration of nicotine released decreased significantly, which is helpful for establishing a method for the rapid evaluation of the processing and selection of excipients of snus products, and provides a new idea for further study of the production of snus pouches and related tobacco products. Moreover, based on data fitting, it can be calculated that the concentration of nicotine in the extraction presented an obvious quadratic relationship with time, and the release of most of the nicotine in the snus pouch, which is held through the gums and palate, was basically completed after similar to 15 min. Such destruction-free simultaneous measurements of snus products are opening up new perspectives for further research about the impact of nicotinoids on smokers' health and cessation programs.
DOI10.1039/d1ay01601f
WOS KeywordSERS ; CAPILLARIES ; NANOPARTICLES ; LIQUIDS ; SMOKE ; FE3+
Indexed BySCI
Language英语
Funding ProjectNational Major Scientific and Technological Special Project for Significant New Drugs Development[2018ZX09J18112] ; Presidential Foundation of Hefei Institutes of Physical Science, Chinese Academy of Sciences[YZJJZX202019]
Funding OrganizationNational Major Scientific and Technological Special Project for Significant New Drugs Development ; Presidential Foundation of Hefei Institutes of Physical Science, Chinese Academy of Sciences
WOS Research AreaChemistry ; Food Science & Technology ; Spectroscopy
WOS SubjectChemistry, Analytical ; Food Science & Technology ; Spectroscopy
WOS IDWOS:000720972700001
PublisherROYAL SOC CHEMISTRY
Citation statistics
Document Type期刊论文
Identifierhttp://ir.hfcas.ac.cn:8080/handle/334002/126579
Collection中国科学院合肥物质科学研究院
Corresponding AuthorTang, Xianghu; Zhu, Donglai
Affiliation1.China Tobacco Yunnan Ind Co Ltd, Yunnan Key Lab Tobacco Chem, Technol Ctr, Kunming 650231, Yunnan, Peoples R China
2.Chinese Acad Sci, Inst Solid State Phys, HFIPS, Hefei 230031, Peoples R China
3.Univ Sci & Technol China, Hefei 230026, Anhui, Peoples R China
4.China Natl Tobacco Qual Supervis & Test Ctr, Zhengzhou 450001, Peoples R China
Recommended Citation
GB/T 7714
Tian, Yongfeng,Tang, Xianghu,Fu, Yaning,et al. Simultaneous extraction and surface enhanced Raman spectroscopy detection for the rapid and reliable identification of nicotine released from snus products[J]. ANALYTICAL METHODS,2021,13.
APA Tian, Yongfeng.,Tang, Xianghu.,Fu, Yaning.,Shang, Shanzhai.,Dong, Gaofeng.,...&Zhu, Donglai.(2021).Simultaneous extraction and surface enhanced Raman spectroscopy detection for the rapid and reliable identification of nicotine released from snus products.ANALYTICAL METHODS,13.
MLA Tian, Yongfeng,et al."Simultaneous extraction and surface enhanced Raman spectroscopy detection for the rapid and reliable identification of nicotine released from snus products".ANALYTICAL METHODS 13(2021).
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