Hepatoid Adenocarcinoma of the Lung

doi:10.1177/15330338211057983

HFCAS OpenIR

	Hepatoid Adenocarcinoma of the Lung
	Li, Meihui 1,2,3,4; Fan, Ying 1,2,3,4; Lu, Hongyang 1,2,3,4
	2021-11-01
发表期刊	TECHNOLOGY IN CANCER RESEARCH & TREATMENT
ISSN	1533-0346
通讯作者	Lu, Hongyang(luhy@zjcc.org.cn)
摘要	Hepatoid adenocarcinoma of the lung (HAL) is an comparatively rare malignant tumor originating from the lung with shorter survival. HAL morphologically and pathologically exhibits hepatocellular carcinoma (HCC)-like characteristics, while its clinical features resemble pulmonary adenocarcinoma. High concentration of alpha-fetoprotein (AFP) is often detected in the serum of HAL patients with no hepatic occupying lesion. Patients with AFP-negative HAL survive a few months longer than those with positive AFP test. HAL is a rare type of carcinoma, so there is a lack of systematic and extensive statistical research. The treatment strategy for HAL is similar to common lung adenocarcinoma. Complete surgical resection and adjuvant chemotherapy are the current major treatments for HAL patients. There are also a few of case reports suggesting that HAL patients may benefit from immunotherapy and targeted therapy. This review focuses on the clinical and pathological features, immunohistochemical staining characteristics, treatment and prognosis of HAL.
关键词	hepatoid adenocarcinoma of the lung (HAL) alpha-fetoprotein (AFP) histopathological characteristics immunohistochemical staining treatment prognosis
DOI	10.1177/15330338211057983
关键词[WOS]	ALPHA-FETOPROTEIN ; GASTRIC-CARCINOMA ; METASTASIS ; FEATURES ; THERAPY ; CANCER
收录类别	SCI
语种	英语
资助项目	Zhejiang Province Medical Science and Technology Project[2020ZH001]
项目资助者	Zhejiang Province Medical Science and Technology Project
WOS研究方向	Oncology
WOS类目	Oncology
WOS记录号	WOS:000726626500001
出版者	SAGE PUBLICATIONS INC
引用统计	被引频次：6[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.hfcas.ac.cn:8080/handle/334002/126777
专题	中国科学院合肥物质科学研究院
通讯作者	Lu, Hongyang
作者单位	1.Univ Chinese Acad Sci, Zhejiang Key Lab Diag & Treatment Technol Thorac, Canc Hosp, Zhejiang Canc Hosp, Beijing 310022, Peoples R China 2.Univ Chinese Acad Sci, Dept Thorac Med Oncol, Zhejiang Canc Hosp, Canc Hosp, Beijing 310022, Peoples R China 3.Chinese Acad Sci, Inst Basic Med & Canc IBMC, Beijing 310022, Peoples R China 4.Wenzhou Med Univ, Clin Med Coll 1, Wenzhou, Peoples R China
推荐引用方式 GB/T 7714	Li, Meihui,Fan, Ying,Lu, Hongyang. Hepatoid Adenocarcinoma of the Lung[J]. TECHNOLOGY IN CANCER RESEARCH & TREATMENT,2021,20.
APA	Li, Meihui,Fan, Ying,&Lu, Hongyang.(2021).Hepatoid Adenocarcinoma of the Lung.TECHNOLOGY IN CANCER RESEARCH & TREATMENT,20.
MLA	Li, Meihui,et al."Hepatoid Adenocarcinoma of the Lung".TECHNOLOGY IN CANCER RESEARCH & TREATMENT 20(2021).