Impairment of Biofilm Formation by TiO2 Photocatalysis through Quorum Quenching

doi:10.1021/acs.est.6603134

	Impairment of Biofilm Formation by TiO2 Photocatalysis through Quorum Quenching
	Xiao, Xiang 1,3; Zhu, Wen-Wen 1; Liu, Qiu-Yue 1; Yuan, Hang2 ; Li, Wen-Wei 3; Wu, Li-Jun2 ; Li, Qian 1; Yu, Han-Qing 3
	2016-11-01
发表期刊	ENVIRONMENTAL SCIENCE & TECHNOLOGY
摘要	The release of nanomaterials into the environment, due to their massive production and application today, has caused ecological and health safety concerns. Semiconductor photocatalysts like TiO2 exhibit cytotoxicity to bacterial cells when exposed to UV irradiation. However, information about their impacts on individual or group bacterial behaviors is limited. In this work, the biofilm formation of Escherichia coli K12 in the presence of TiO2 with and without UV irradiation was investigated and biofilm formation was found not to be affected under the sole application of TiO2 or UV irradiation. However, biofilm development was substantially delayed by TiO2 under UV irradiation, although no obvious cytotoxicity to cell growth was observed. The reactive oxygen species photogenerated by TiO2 were found to quench the autoinducer 2 (AI-2) signals secreted by E. coli K12. As a result, the initiation of quorum sensing for biofilm formation activated by AI-2 was restrained. The expressions of two biofilm-formation-related genes, motA and rcsB, were also suppressed. A dose of an AI-2 precursor, 4,5-dihydroxy-2,3-pentanedione, effectively restored the biofilm development. These results show that the photoexcited TiO2 could suppress biofilm formation through quenching AI-2 signals. This work may facilitate a better understanding about the ecological effects of increasingly released nanomaterials and provide implications for development of antifouling membranes.
文章类型	Article
WOS标题词	Science & Technology ; Technology ; Life Sciences & Biomedicine
DOI	10.1021/acs.est.6603134
关键词[WOS]	ESCHERICHIA-COLI ; ANTIMICROBIAL ACTIVITY ; GENE-EXPRESSION ; BACTERIAL ; DEGRADATION ; NANOCOMPOSITE ; COMMUNICATION ; AUTOINDUCER-2 ; ARCHITECTURE ; OXIDATION
收录类别	SCI
语种	英语
项目资助者	National Basic Research Program of China(2013CB934302) ; National Basic Research Program of China(2013CB934302) ; National Basic Research Program of China(2013CB934302) ; National Basic Research Program of China(2013CB934302) ; National Natural Science Foundation of China(51478208 ; National Natural Science Foundation of China(51478208 ; National Natural Science Foundation of China(51478208 ; National Natural Science Foundation of China(51478208 ; 21477120 ; 21477120 ; 21477120 ; 21477120 ; 21590812) ; 21590812) ; 21590812) ; 21590812)
WOS研究方向	Engineering ; Environmental Sciences & Ecology
WOS类目	Engineering, Environmental ; Environmental Sciences
WOS记录号	WOS:000386991100053
引用统计	被引频次：44[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.hfcas.ac.cn:8080/handle/334002/30243
专题	技术生物与农业工程研究所
作者单位	1.Jiangsu Univ, Sch Environm & Safety Engn, Zhenjiang 212013, Peoples R China 2.Chinese Acad Sci, Inst Tech Biol & Agr Engn, Key Lab Ion Beam Bioengn, Hefei 230031, Peoples R China 3.Univ Sci & Technol China, Dept Chem, CAS Key Lab Urban Pollutant Convers, Hefei 230026, Peoples R China
推荐引用方式 GB/T 7714	Xiao, Xiang,Zhu, Wen-Wen,Liu, Qiu-Yue,et al. Impairment of Biofilm Formation by TiO2 Photocatalysis through Quorum Quenching[J]. ENVIRONMENTAL SCIENCE & TECHNOLOGY,2016,50(21):11895-11902.
APA	Xiao, Xiang.,Zhu, Wen-Wen.,Liu, Qiu-Yue.,Yuan, Hang.,Li, Wen-Wei.,...&Yu, Han-Qing.(2016).Impairment of Biofilm Formation by TiO2 Photocatalysis through Quorum Quenching.ENVIRONMENTAL SCIENCE & TECHNOLOGY,50(21),11895-11902.
MLA	Xiao, Xiang,et al."Impairment of Biofilm Formation by TiO2 Photocatalysis through Quorum Quenching".ENVIRONMENTAL SCIENCE & TECHNOLOGY 50.21(2016):11895-11902.

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