Institutional Repository of Chinese Academy of Sciences, Institute of Plasma Physics, Hefei 230031, Anhui, Peoples R China
Cold atmospheric-pressure air plasma treatment of C6 glioma cells: effects of reactive oxygen species in the medium produced by the plasma on cell death | |
Wang, Yuyang1; Cheng, Cheng2; Gao, Peng1; Li, Shaopeng1,2; Shen, Jie2; Lan, Yan; Yu, Yongqiang1; Chu, Paul K.3 | |
2017-02-01 | |
发表期刊 | PLASMA SCIENCE & TECHNOLOGY |
摘要 | An atmospheric-pressure air plasma is employed to treat C6 glioma cells in vitro. To elucidate on the mechanism causing cell death and role of reactive species (RS) in the medium produced by the plasma, the concentration of the long-lived RS such as hydrogen peroxide, nitrate, and ozone in the plasma-treated liquid (phosphate-buffered saline solution) is measured. When vitamin C is added to the medium as a ROS quencher, the viability of C6 glioma cells after the plasma treatment is different from that without vitamin C. The results demonstrate that reactive oxygen species (ROS) such as H2O2, and O-3 constitute the main factors for inactivation of C6 glioma cells and the reactive nitrogen species (RNS) may only play an auxiliary role in cell death. |
文章类型 | Article |
关键词 | Atmospheric Pressure Air Plasma Reactive Species Cell Death |
WOS标题词 | Science & Technology ; Physical Sciences |
DOI | 10.1088/2058-6272/19/2/025503 |
关键词[WOS] | DISCHARGE |
收录类别 | SCI |
语种 | 英语 |
项目资助者 | Education and Research Foundation of Anhui Province(KJ2015A327) ; Education and Research Foundation of Anhui Province(KJ2015A327) ; Education and Research Foundation of Anhui Province(KJ2015A327) ; Education and Research Foundation of Anhui Province(KJ2015A327) ; Education and Research Foundation of Anhui Province(KJ2015A327) ; Education and Research Foundation of Anhui Province(KJ2015A327) ; Education and Research Foundation of Anhui Province(KJ2015A327) ; Education and Research Foundation of Anhui Province(KJ2015A327) ; Science Foundation of Institute of Plasma Physics, Chinese Academy of Sciences(DSJJ-14-YY02) ; Science Foundation of Institute of Plasma Physics, Chinese Academy of Sciences(DSJJ-14-YY02) ; Science Foundation of Institute of Plasma Physics, Chinese Academy of Sciences(DSJJ-14-YY02) ; Science Foundation of Institute of Plasma Physics, Chinese Academy of Sciences(DSJJ-14-YY02) ; Science Foundation of Institute of Plasma Physics, Chinese Academy of Sciences(DSJJ-14-YY02) ; Science Foundation of Institute of Plasma Physics, Chinese Academy of Sciences(DSJJ-14-YY02) ; Science Foundation of Institute of Plasma Physics, Chinese Academy of Sciences(DSJJ-14-YY02) ; Science Foundation of Institute of Plasma Physics, Chinese Academy of Sciences(DSJJ-14-YY02) ; Hong Kong Research Grants Council (RGC) General Research Funds (GRF)(CityU 11301215) ; Hong Kong Research Grants Council (RGC) General Research Funds (GRF)(CityU 11301215) ; Hong Kong Research Grants Council (RGC) General Research Funds (GRF)(CityU 11301215) ; Hong Kong Research Grants Council (RGC) General Research Funds (GRF)(CityU 11301215) ; Hong Kong Research Grants Council (RGC) General Research Funds (GRF)(CityU 11301215) ; Hong Kong Research Grants Council (RGC) General Research Funds (GRF)(CityU 11301215) ; Hong Kong Research Grants Council (RGC) General Research Funds (GRF)(CityU 11301215) ; Hong Kong Research Grants Council (RGC) General Research Funds (GRF)(CityU 11301215) |
WOS研究方向 | Physics |
WOS类目 | Physics, Fluids & Plasmas |
WOS记录号 | WOS:000398145700010 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.hfcas.ac.cn:8080/handle/334002/31768 |
专题 | 中科院等离子体物理研究所 |
作者单位 | 1.Anhui Med Univ, Affiliated Hosp 1, Hefei 230032, Peoples R China 2.Chinese Acad Sci, Inst Plasma Phys, Hefei 230031, Peoples R China 3.City Univ Hong Kong, Dept Phys & Mat Sci, TatChee Ave, Kowloon, Hong Kong, Peoples R China |
推荐引用方式 GB/T 7714 | Wang, Yuyang,Cheng, Cheng,Gao, Peng,et al. Cold atmospheric-pressure air plasma treatment of C6 glioma cells: effects of reactive oxygen species in the medium produced by the plasma on cell death[J]. PLASMA SCIENCE & TECHNOLOGY,2017,19(2):1-6. |
APA | Wang, Yuyang.,Cheng, Cheng.,Gao, Peng.,Li, Shaopeng.,Shen, Jie.,...&Chu, Paul K..(2017).Cold atmospheric-pressure air plasma treatment of C6 glioma cells: effects of reactive oxygen species in the medium produced by the plasma on cell death.PLASMA SCIENCE & TECHNOLOGY,19(2),1-6. |
MLA | Wang, Yuyang,et al."Cold atmospheric-pressure air plasma treatment of C6 glioma cells: effects of reactive oxygen species in the medium produced by the plasma on cell death".PLASMA SCIENCE & TECHNOLOGY 19.2(2017):1-6. |
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