c-Abl inhibition mitigates diet-induced obesity through improving insulin sensitivity of subcutaneous fat in mice

doi:10.1007/s00125-016-4202-2

HFCAS OpenIR > 中科院强磁场科学中心

	c-Abl inhibition mitigates diet-induced obesity through improving insulin sensitivity of subcutaneous fat in mice
	Wu, Rong 1,2; Sun, Jian-guang 1,3; Wang, Ji-qiu 4; Li, Binhua 5; Liu, Qingsong5 ; Ning, Guang 4; Jin, Wanzhu 6; Yuan, Zengqiang 1,2,7
	2017-05-01
发表期刊	DIABETOLOGIA
摘要	High-energy diets are among the main causes of the global epidemic of metabolic disorders, including obesity and type 2 diabetes. The mechanisms of high-energy-diet-induced metabolic disorders are complex and largely unknown. The non-receptor tyrosine kinase c-Abl plays an important role in adipogenesis in vitro but its role in vivo in the regulation of metabolism is still elusive. Hence, we sought to address the role of c-Abl in diet-induced obesity and obesity-associated insulin resistance.
文章类型	Article
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
DOI	10.1007/s00125-016-4202-2
关键词[WOS]	CHRONIC MYELOID-LEUKEMIA ; CHRONIC MYELOGENOUS LEUKEMIA ; HUMAN ADIPOSE-TISSUE ; TYROSINE KINASE ; ADIPOCYTE DIFFERENTIATION ; ADIPONECTIN LEVELS ; IMATINIB MESYLATE ; CELLS ROLE ; RESISTANCE ; STRESS
收录类别	SCI
语种	英语
项目资助者	National Science Foundation of China(81630026 ; National Science Foundation of China(81630026 ; National Science Foundation of China(81630026 ; National Science Foundation of China(81630026 ; National Science Foundation of China(81630026 ; National Science Foundation of China(81630026 ; National Science Foundation of China(81630026 ; National Science Foundation of China(81630026 ; National Science Foundation of China(81630026 ; National Science Foundation of China(81630026 ; National Science Foundation of China(81630026 ; National Science Foundation of China(81630026 ; National Science Foundation of China(81630026 ; National Science Foundation of China(81630026 ; National Science Foundation of China(81630026 ; National Science Foundation of China(81630026 ; National Basic Research Program of China(973-2012CB910701 ; National Basic Research Program of China(973-2012CB910701 ; National Basic Research Program of China(973-2012CB910701 ; National Basic Research Program of China(973-2012CB910701 ; National Basic Research Program of China(973-2012CB910701 ; National Basic Research Program of China(973-2012CB910701 ; National Basic Research Program of China(973-2012CB910701 ; National Basic Research Program of China(973-2012CB910701 ; National Basic Research Program of China(973-2012CB910701 ; National Basic Research Program of China(973-2012CB910701 ; National Basic Research Program of China(973-2012CB910701 ; National Basic Research Program of China(973-2012CB910701 ; National Basic Research Program of China(973-2012CB910701 ; National Basic Research Program of China(973-2012CB910701 ; National Basic Research Program of China(973-2012CB910701 ; National Basic Research Program of China(973-2012CB910701 ; Chinese Academy of Sciences ; Chinese Academy of Sciences ; Chinese Academy of Sciences ; Chinese Academy of Sciences ; Chinese Academy of Sciences ; Chinese Academy of Sciences ; Chinese Academy of Sciences ; Chinese Academy of Sciences ; Chinese Academy of Sciences ; Chinese Academy of Sciences ; Chinese Academy of Sciences ; Chinese Academy of Sciences ; Chinese Academy of Sciences ; Chinese Academy of Sciences ; Chinese Academy of Sciences ; Chinese Academy of Sciences ; 81125010 ; 81125010 ; 81125010 ; 81125010 ; 81125010 ; 81125010 ; 81125010 ; 81125010 ; 81125010 ; 81125010 ; 81125010 ; 81125010 ; 81125010 ; 81125010 ; 81125010 ; 81125010 ; 2013DFA31990) ; 2013DFA31990) ; 2013DFA31990) ; 2013DFA31990) ; 2013DFA31990) ; 2013DFA31990) ; 2013DFA31990) ; 2013DFA31990) ; 2013DFA31990) ; 2013DFA31990) ; 2013DFA31990) ; 2013DFA31990) ; 2013DFA31990) ; 2013DFA31990) ; 2013DFA31990) ; 2013DFA31990) ; 81030025) ; 81030025) ; 81030025) ; 81030025) ; 81030025) ; 81030025) ; 81030025) ; 81030025) ; 81030025) ; 81030025) ; 81030025) ; 81030025) ; 81030025) ; 81030025) ; 81030025) ; 81030025)
WOS研究方向	Endocrinology & Metabolism
WOS类目	Endocrinology & Metabolism
WOS记录号	WOS:000398997400018
引用统计	被引频次：8[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.hfcas.ac.cn:8080/handle/334002/33401
专题	中科院强磁场科学中心
作者单位	1.Chinese Acad Sci, Inst Biophys, State Key Lab Brain & Cognit Sci, 15 Datun Rd, Beijing 100101, Peoples R China 2.Univ Chinese Acad Sci, Coll Life Sci, Beijing, Peoples R China 3.Univ Chinese Acad Sci, Sino Danish Ctr Neurosci Program, Beijing, Peoples R China 4.Shanghai Jiao Tong Univ, Ruijin Hosp, Sch Med, Shanghai, Peoples R China 5.Chinese Acad Sci, High Field Magnet Lab, Hefei, Anhui, Peoples R China 6.Chinese Acad Sci, Inst Zool, Key Lab Anim Ecol & Conservat Biol, 1 Beichen West Rd, Beijing 100101, Peoples R China 7.Beijing Inst Brain Disorders, Ctr Alzheimers Dis, Beijing, Peoples R China
推荐引用方式 GB/T 7714	Wu, Rong,Sun, Jian-guang,Wang, Ji-qiu,et al. c-Abl inhibition mitigates diet-induced obesity through improving insulin sensitivity of subcutaneous fat in mice[J]. DIABETOLOGIA,2017,60(5):900-910.
APA	Wu, Rong.,Sun, Jian-guang.,Wang, Ji-qiu.,Li, Binhua.,Liu, Qingsong.,...&Yuan, Zengqiang.(2017).c-Abl inhibition mitigates diet-induced obesity through improving insulin sensitivity of subcutaneous fat in mice.DIABETOLOGIA,60(5),900-910.
MLA	Wu, Rong,et al."c-Abl inhibition mitigates diet-induced obesity through improving insulin sensitivity of subcutaneous fat in mice".DIABETOLOGIA 60.5(2017):900-910.