Macro-morphological characterization and kinetics of Mortierella alpina colonies during batch cultivation

doi:10.1371/journal.pone.0192803

HFCAS OpenIR

	Macro-morphological characterization and kinetics of Mortierella alpina colonies during batch cultivation
	Fang, Xue 1,2; Zhao, Genhai1 ; Dai, Jun1 ; Liu, Hui 1; Wang, Peng 1; Wang, Li 1; Song, Junying 1; Zheng, Zhiming1
	2018-08-07
发表期刊	PLOS ONE
ISSN	1932-6203
通讯作者	Zhao, Genhai(zhgh327@126.com) ; Zheng, Zhiming(zhengzhiming2014@163.com)
摘要	An effective method for research of macro-morphological characterization and its kinetics was developed by studying the macro-morphological characteristics of Mortierella alpina, an oleaginous zygomycete widely used to produce lipids rich in PUFA, in function of culture medium composition and to link morphological features of fungus with the level of lipid production. A number of distinct morphological forms including hollow pellets, fluffy pellets and freely dispersed mycelia were obtained by changing the fermentation factors. By fitting a Logistic curve, the maximum specific growth rate (mu(max))was obtained, which determined the final mycelia morphology. mu(max) of 0.6584 in three kind of morphological forms is the more appropriate. According to the Luedeking-Piret equation fitting, alpha not equal 0 and beta not equal 0 lipid production was partially associated with the hyphal growth, fluffy pellets which turn glucose into lipid was more effective than the other two kinds of morphological forms.
DOI	10.1371/journal.pone.0192803
关键词[WOS]	ARACHIDONIC-ACID PRODUCTION ; IMAGE-ANALYSIS ; FILAMENTOUS MICROORGANISMS ; LOVASTATIN PRODUCTION ; ASPERGILLUS-TERREUS ; MYCELIAL MORPHOLOGY ; PELLET MORPHOLOGY ; FATTY-ACIDS ; CULTURES ; FERMENTATION
收录类别	SCI
语种	英语
资助项目	National High Technology Research and Development Program of China[2014AA021704] ; Anhui Provincial Natural Science Foundation[1308085MA07] ; National High Technology Research and Development Program of China[2014AA021704] ; Anhui Provincial Natural Science Foundation[1308085MA07]
项目资助者	National High Technology Research and Development Program of China ; National High Technology Research and Development Program of China ; National High Technology Research and Development Program of China ; National High Technology Research and Development Program of China ; National High Technology Research and Development Program of China ; National High Technology Research and Development Program of China ; National High Technology Research and Development Program of China ; National High Technology Research and Development Program of China ; National High Technology Research and Development Program of China ; National High Technology Research and Development Program of China ; National High Technology Research and Development Program of China ; National High Technology Research and Development Program of China ; National High Technology Research and Development Program of China ; National High Technology Research and Development Program of China ; National High Technology Research and Development Program of China ; National High Technology Research and Development Program of China ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; National High Technology Research and Development Program of China ; National High Technology Research and Development Program of China ; National High Technology Research and Development Program of China ; National High Technology Research and Development Program of China ; National High Technology Research and Development Program of China ; National High Technology Research and Development Program of China ; National High Technology Research and Development Program of China ; National High Technology Research and Development Program of China ; National High Technology Research and Development Program of China ; National High Technology Research and Development Program of China ; National High Technology Research and Development Program of China ; National High Technology Research and Development Program of China ; National High Technology Research and Development Program of China ; National High Technology Research and Development Program of China ; National High Technology Research and Development Program of China ; National High Technology Research and Development Program of China ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation ; Anhui Provincial Natural Science Foundation
WOS研究方向	Science & Technology - Other Topics
WOS类目	Multidisciplinary Sciences
WOS记录号	WOS:000441129300001
出版者	PUBLIC LIBRARY SCIENCE
引用统计	被引频次：5[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.hfcas.ac.cn:8080/handle/334002/37724
专题	中国科学院合肥物质科学研究院
通讯作者	Zhao, Genhai; Zheng, Zhiming
作者单位	1.Chinese Acad Sci, Hefei Inst Phys Sci, Key Lab High Magnet Field & Ion Beam Phys Biol, Hefei, Anhui, Peoples R China 2.Univ Sci & Technol China, Hefei, Anhui, Peoples R China
推荐引用方式 GB/T 7714	Fang, Xue,Zhao, Genhai,Dai, Jun,et al. Macro-morphological characterization and kinetics of Mortierella alpina colonies during batch cultivation[J]. PLOS ONE,2018,13(8):11.
APA	Fang, Xue.,Zhao, Genhai.,Dai, Jun.,Liu, Hui.,Wang, Peng.,...&Zheng, Zhiming.(2018).Macro-morphological characterization and kinetics of Mortierella alpina colonies during batch cultivation.PLOS ONE,13(8),11.
MLA	Fang, Xue,et al."Macro-morphological characterization and kinetics of Mortierella alpina colonies during batch cultivation".PLOS ONE 13.8(2018):11.