Label-free ferrule-top optical fiber micro-cantilever biosensor

doi:10.1016/j.sna.2018.07.014

HFCAS OpenIR

	Label-free ferrule-top optical fiber micro-cantilever biosensor
	Li, J.1,2; Zhou, Y. X.3; Guo, Y. X.2; Wang, G. Y.1; Maier, R. R. J.4; Hand, D. P.4; MacPherson, W. N.4
	2018-09-01
发表期刊	SENSORS AND ACTUATORS A-PHYSICAL
ISSN	0924-4247
通讯作者	Li, J.(ljsiom@aiofm.ac.cn)
摘要	Micro-cantilever sensors have shown great promise in a wide range of applications including chemical medical and biological sensing. However, many of these devices are based upon a sensor 'chip' that requires careful alignment between the cantilever and the read-out system, which can be challenging. Furthermore, optical interrogation typically involves a bulky free-space system. Optical fiber addressed cantilevers have been reported previously in the literature and in this paper we propose techniques to design and fabricate polymer micro-cantilevers onto the end of standard single mode fibers using ns-laser machining. The cantilever will deflect and thereby observing biological binding between species of interests and activated cantilevers. Proof-of-concept experiments demonstrate that the sensor is capable of detecting Listeria food pathogen concentrations with a minimum level of less than 10(5)cfu/ml. (C) 2018 Elsevier B.V. All rights reserved.
关键词	Ferrule-top cantilever Label-free Bio-sensing ns-Laser machining
DOI	10.1016/j.sna.2018.07.014
关键词[WOS]	SENSORS ; ARRAY ; MICROCANTILEVERS ; TECHNOLOGY ; MONOLAYERS ; GOLD
收录类别	SCI
语种	英语
资助项目	Innovative Manufacturing Research Centre under EPSRC[EP/F02553X/1] ; Renishaw plc. ; Innovative Manufacturing Research Centre under EPSRC[EP/F02553X/1] ; Renishaw plc.
项目资助者	Innovative Manufacturing Research Centre under EPSRC ; Innovative Manufacturing Research Centre under EPSRC ; Innovative Manufacturing Research Centre under EPSRC ; Innovative Manufacturing Research Centre under EPSRC ; Innovative Manufacturing Research Centre under EPSRC ; Innovative Manufacturing Research Centre under EPSRC ; Innovative Manufacturing Research Centre under EPSRC ; Innovative Manufacturing Research Centre under EPSRC ; Renishaw plc. ; Renishaw plc. ; Renishaw plc. ; Renishaw plc. ; Renishaw plc. ; Renishaw plc. ; Renishaw plc. ; Renishaw plc. ; Innovative Manufacturing Research Centre under EPSRC ; Innovative Manufacturing Research Centre under EPSRC ; Innovative Manufacturing Research Centre under EPSRC ; Innovative Manufacturing Research Centre under EPSRC ; Innovative Manufacturing Research Centre under EPSRC ; Innovative Manufacturing Research Centre under EPSRC ; Innovative Manufacturing Research Centre under EPSRC ; Innovative Manufacturing Research Centre under EPSRC ; Renishaw plc. ; Renishaw plc. ; Renishaw plc. ; Renishaw plc. ; Renishaw plc. ; Renishaw plc. ; Renishaw plc. ; Renishaw plc.
WOS研究方向	Engineering ; Instruments & Instrumentation
WOS类目	Engineering, Electrical & Electronic ; Instruments & Instrumentation
WOS记录号	WOS:000447097200062
出版者	ELSEVIER SCIENCE SA
引用统计	被引频次：9[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.hfcas.ac.cn:8080/handle/334002/39426
专题	中国科学院合肥物质科学研究院
通讯作者	Li, J.
作者单位	1.Chinese Acad Sci, Anhui Inst Opt & Fine Mech, Hefei 230031, Anhui, Peoples R China 2.Xian Univ Sci & Technol, Sch Safety Engn, Xian 710054, Shaanxi, Peoples R China 3.Senboll Biotechnol Co Ltd, Shenzhen 518118, Peoples R China 4.Heriot Watt Univ, Inst Photon & Quantum Sci, Edinburgh, Midlothian, Scotland
第一作者单位	中科院安徽光学精密机械研究所
通讯作者单位	中科院安徽光学精密机械研究所
推荐引用方式 GB/T 7714	Li, J.,Zhou, Y. X.,Guo, Y. X.,et al. Label-free ferrule-top optical fiber micro-cantilever biosensor[J]. SENSORS AND ACTUATORS A-PHYSICAL,2018,280:505-512.
APA	Li, J..,Zhou, Y. X..,Guo, Y. X..,Wang, G. Y..,Maier, R. R. J..,...&MacPherson, W. N..(2018).Label-free ferrule-top optical fiber micro-cantilever biosensor.SENSORS AND ACTUATORS A-PHYSICAL,280,505-512.
MLA	Li, J.,et al."Label-free ferrule-top optical fiber micro-cantilever biosensor".SENSORS AND ACTUATORS A-PHYSICAL 280(2018):505-512.