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NIR-responsive carbon-based nanocarriers for switchable on/off drug release and synergistic cancer therapy
Nie, Rongrong1; Liu, Hongji2; Hu, Lin2; Gu, Xinyu3; Qian, Junchao4; Wang, Hui2
2018-12-21
Source PublicationJOURNAL OF MATERIALS CHEMISTRY B
ISSN2050-750X
Corresponding AuthorWang, Hui(hw39@hmfl.ac.cn)
AbstractHerein, we present a light-switchable drug delivery system based on chitosan-gated carbon-based nanocarriers (CGC NCs) that exhibit a loading capacity for doxorubicin as high as similar to 89.65 wt% and controlled on/off release with/without NIR irradiation. In vitro and in vivo results show that the CGC NCs manifest high efficacy for cancer therapy through a synergistic effect of combined chemo-photothermal treatment.
DOI10.1039/c8tb02398k
WOS KeywordPHOTOTHERMAL THERAPY ; DELIVERY SYSTEMS ; IRON-OXIDE ; CHEMOTHERAPY ; NANOPARTICLES ; CARRIER ; COMBINATION ; NANOTECHNOLOGY ; NANOHYBRIDS ; BEHAVIOR
Indexed BySCI
Language英语
Funding ProjectNational Key Technologies RD Program[2016 YFA0401801] ; Chinese Academy of Sciences[1600000012] ; National Key Technologies RD Program[2016 YFA0401801] ; Chinese Academy of Sciences[1600000012]
Funding OrganizationNational Key Technologies RD Program ; National Key Technologies RD Program ; National Key Technologies RD Program ; National Key Technologies RD Program ; Chinese Academy of Sciences ; Chinese Academy of Sciences ; Chinese Academy of Sciences ; Chinese Academy of Sciences ; National Key Technologies RD Program ; National Key Technologies RD Program ; National Key Technologies RD Program ; National Key Technologies RD Program ; Chinese Academy of Sciences ; Chinese Academy of Sciences ; Chinese Academy of Sciences ; Chinese Academy of Sciences
WOS Research AreaMaterials Science
WOS SubjectMaterials Science, Biomaterials
WOS IDWOS:000452319700002
PublisherROYAL SOC CHEMISTRY
Citation statistics
Cited Times:6[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.hfcas.ac.cn:8080/handle/334002/41066
Collection中科院强磁场科学中心
Corresponding AuthorWang, Hui
Affiliation1.Nanjing Univ, Med Sch, Nanjing Stomatol Hosp, Nanjing 210008, Jiangsu, Peoples R China
2.Chinese Acad Sci, Hefei Inst Phys Sci, High Magnet Field Lab, Anhui Key Lab Condensed Matter Phys Extreme Condi, Hefei 230031, Anhui, Peoples R China
3.Univ Washington, Dept Biochem, Seattle, WA 98195 USA
4.Chinese Acad Sci, Hefei Inst Phys Sci, Hefei Canc Hosp, Hefei 230031, Anhui, Peoples R China
Recommended Citation
GB/T 7714
Nie, Rongrong,Liu, Hongji,Hu, Lin,et al. NIR-responsive carbon-based nanocarriers for switchable on/off drug release and synergistic cancer therapy[J]. JOURNAL OF MATERIALS CHEMISTRY B,2018,6(47):7794-7799.
APA Nie, Rongrong,Liu, Hongji,Hu, Lin,Gu, Xinyu,Qian, Junchao,&Wang, Hui.(2018).NIR-responsive carbon-based nanocarriers for switchable on/off drug release and synergistic cancer therapy.JOURNAL OF MATERIALS CHEMISTRY B,6(47),7794-7799.
MLA Nie, Rongrong,et al."NIR-responsive carbon-based nanocarriers for switchable on/off drug release and synergistic cancer therapy".JOURNAL OF MATERIALS CHEMISTRY B 6.47(2018):7794-7799.
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