Institutional Repository of Chinese Acad Sci, High Field Magnet Lab,Hefei 230031, Anhui, Peoples R China
| NIR-responsive carbon-based nanocarriers for switchable on/off drug release and synergistic cancer therapy | |
Nie, Rongrong1; Liu, Hongji2; Hu, Lin2 ; Gu, Xinyu3; Qian, Junchao4; Wang, Hui2
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| 2018-12-21 | |
| Source Publication | JOURNAL OF MATERIALS CHEMISTRY B
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| ISSN | 2050-750X |
| Corresponding Author | Wang, Hui(hw39@hmfl.ac.cn) |
| Abstract | Herein, we present a light-switchable drug delivery system based on chitosan-gated carbon-based nanocarriers (CGC NCs) that exhibit a loading capacity for doxorubicin as high as similar to 89.65 wt% and controlled on/off release with/without NIR irradiation. In vitro and in vivo results show that the CGC NCs manifest high efficacy for cancer therapy through a synergistic effect of combined chemo-photothermal treatment. |
| DOI | 10.1039/c8tb02398k |
| WOS Keyword | PHOTOTHERMAL THERAPY ; DELIVERY SYSTEMS ; IRON-OXIDE ; CHEMOTHERAPY ; NANOPARTICLES ; CARRIER ; COMBINATION ; NANOTECHNOLOGY ; NANOHYBRIDS ; BEHAVIOR |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | National Key Technologies RD Program[2016 YFA0401801] ; Chinese Academy of Sciences[1600000012] ; National Key Technologies RD Program[2016 YFA0401801] ; Chinese Academy of Sciences[1600000012] |
| Funding Organization | National Key Technologies RD Program ; National Key Technologies RD Program ; National Key Technologies RD Program ; National Key Technologies RD Program ; Chinese Academy of Sciences ; Chinese Academy of Sciences ; Chinese Academy of Sciences ; Chinese Academy of Sciences ; National Key Technologies RD Program ; National Key Technologies RD Program ; National Key Technologies RD Program ; National Key Technologies RD Program ; Chinese Academy of Sciences ; Chinese Academy of Sciences ; Chinese Academy of Sciences ; Chinese Academy of Sciences |
| WOS Research Area | Materials Science |
| WOS Subject | Materials Science, Biomaterials |
| WOS ID | WOS:000452319700002 |
| Publisher | ROYAL SOC CHEMISTRY |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.hfcas.ac.cn:8080/handle/334002/41066 |
| Collection | 中科院强磁场科学中心 |
| Corresponding Author | Wang, Hui |
| Affiliation | 1.Nanjing Univ, Med Sch, Nanjing Stomatol Hosp, Nanjing 210008, Jiangsu, Peoples R China 2.Chinese Acad Sci, Hefei Inst Phys Sci, High Magnet Field Lab, Anhui Key Lab Condensed Matter Phys Extreme Condi, Hefei 230031, Anhui, Peoples R China 3.Univ Washington, Dept Biochem, Seattle, WA 98195 USA 4.Chinese Acad Sci, Hefei Inst Phys Sci, Hefei Canc Hosp, Hefei 230031, Anhui, Peoples R China |
| Recommended Citation GB/T 7714 | Nie, Rongrong,Liu, Hongji,Hu, Lin,et al. NIR-responsive carbon-based nanocarriers for switchable on/off drug release and synergistic cancer therapy[J]. JOURNAL OF MATERIALS CHEMISTRY B,2018,6(47):7794-7799. |
| APA | Nie, Rongrong,Liu, Hongji,Hu, Lin,Gu, Xinyu,Qian, Junchao,&Wang, Hui.(2018).NIR-responsive carbon-based nanocarriers for switchable on/off drug release and synergistic cancer therapy.JOURNAL OF MATERIALS CHEMISTRY B,6(47),7794-7799. |
| MLA | Nie, Rongrong,et al."NIR-responsive carbon-based nanocarriers for switchable on/off drug release and synergistic cancer therapy".JOURNAL OF MATERIALS CHEMISTRY B 6.47(2018):7794-7799. |
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