A Novel Solution-auto-introduction Electrophoresis Microchip Based on Capillary Force

	A Novel Solution-auto-introduction Electrophoresis Microchip Based on Capillary Force
	Yang, Mingpeng 1,2; Huang, Zhe 1,2; Chang, Jianguo 1,2; You, Hui1,2
	2018-11-01
发表期刊	ANALYTICAL SCIENCES
ISSN	0910-6340
通讯作者	You, Hui(usmlhy@iim.ac.cn)
摘要	A novel solution-auto-introduction electrophoresis microchip based on capillary force aimed at improving portability is proposed in this paper. Two kinds of materials with micropores, poly(vinyl alcohol) (PVA)-sponge and nano-sponge, were employed as suction pumps that realized the introduction of a running buffer into the reservoirs. The surfaces of the microchannels in the microchips were modified by PVA to improve the moving velocity of the running buffer and the detection performance of the microchip. The introduction velocity of a running buffer in the PVA-coated microchannels was increased by two times compared with that in the native microchannels. The electrophoresis detection performance of several microchips composed of different microchannels and suction materials were evaluated comparatively. The results indicated that the surface coating of PVA can significantly improve the repeatability of the detection results by 20 - 40%, and the noise of the detected signals in the PVA-coated microchips is much lower than that in the native microchips. The proposed solution-auto-introduction electrophoresis microchip is a successful attempt that completely avoids the external connectors to accomplish the auto-introduction of running buffer. The solution-auto-introduction method provides a new train of thought for portable detection instruments with electrophoresis microchips in the future.
关键词	Electrophoresis microchip solution-auto-introduction suction materials
关键词[WOS]	CONTACTLESS CONDUCTIVITY DETECTOR ; LARGE-VOLUME SAMPLE ; INJECTION ; DRIVEN ; DEVICE
收录类别	SCI
语种	英语
资助项目	National Key Technology Research and Development Program of the Ministry of Science and Technology of China[SQ2015BA0800060] ; Science and Technology Research Project of Anhui Province, China[1501031088] ; National Key Technology Research and Development Program of the Ministry of Science and Technology of China[SQ2015BA0800060] ; Science and Technology Research Project of Anhui Province, China[1501031088]
项目资助者	National Key Technology Research and Development Program of the Ministry of Science and Technology of China ; National Key Technology Research and Development Program of the Ministry of Science and Technology of China ; National Key Technology Research and Development Program of the Ministry of Science and Technology of China ; National Key Technology Research and Development Program of the Ministry of Science and Technology of China ; Science and Technology Research Project of Anhui Province, China ; Science and Technology Research Project of Anhui Province, China ; Science and Technology Research Project of Anhui Province, China ; Science and Technology Research Project of Anhui Province, China ; National Key Technology Research and Development Program of the Ministry of Science and Technology of China ; National Key Technology Research and Development Program of the Ministry of Science and Technology of China ; National Key Technology Research and Development Program of the Ministry of Science and Technology of China ; National Key Technology Research and Development Program of the Ministry of Science and Technology of China ; Science and Technology Research Project of Anhui Province, China ; Science and Technology Research Project of Anhui Province, China ; Science and Technology Research Project of Anhui Province, China ; Science and Technology Research Project of Anhui Province, China
WOS研究方向	Chemistry
WOS类目	Chemistry, Analytical
WOS记录号	WOS:000452249300011
出版者	JAPAN SOC ANALYTICAL CHEMISTRY
引用统计	被引频次：5[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.hfcas.ac.cn:8080/handle/334002/41131
专题	中科院合肥智能机械研究所
通讯作者	You, Hui
作者单位	1.Chinese Acad Sci, Inst Intelligent Machines, Hefei 23003, Anhui, Peoples R China 2.Univ Sci & Technol China, Hefei 230026, Anhui, Peoples R China
推荐引用方式 GB/T 7714	Yang, Mingpeng,Huang, Zhe,Chang, Jianguo,et al. A Novel Solution-auto-introduction Electrophoresis Microchip Based on Capillary Force[J]. ANALYTICAL SCIENCES,2018,34(11):1285-1290.
APA	Yang, Mingpeng,Huang, Zhe,Chang, Jianguo,&You, Hui.(2018).A Novel Solution-auto-introduction Electrophoresis Microchip Based on Capillary Force.ANALYTICAL SCIENCES,34(11),1285-1290.
MLA	Yang, Mingpeng,et al."A Novel Solution-auto-introduction Electrophoresis Microchip Based on Capillary Force".ANALYTICAL SCIENCES 34.11(2018):1285-1290.