Surface-Enhanced Raman Spectroscopy for Trace Detection of Tetracycline and Dicyandiamide in Milk Using Transparent Substrate of Ag Nanoparticle Arrays

doi:10.1021/acsanm.0c01389

HFCAS OpenIR

	Surface-Enhanced Raman Spectroscopy for Trace Detection of Tetracycline and Dicyandiamide in Milk Using Transparent Substrate of Ag Nanoparticle Arrays
	Muhammad, Muhammad 1,2; Yan, Bin 1,2; Yao, Guohua1 ; Chao, Kuanglin 3; Zhu, Chuhong 4; Huang, Qing1,2
	2020-07-24
发表期刊	ACS APPLIED NANO MATERIALS
ISSN	2574-0970
通讯作者	Huang, Qing(huangq@ipp.ac.cn)
摘要	Tetracyline (TC) is an antibiotic utilized in dairy livestock, which can leave trace residues in milk and other dairy products. Dicyandiamide (DCD), a grassland fertilizer, but also potentially an adulterant to increase milk apparent protein content, has been found in milk products that were subsequently banned. Both these chemicals can pose human health risks via the consumption of dairy foods, and therefore rapid, simple detection methodologies are necessary. Herein, we fabricated a transparent and homogeneous substrate by fabricating silver nanoparticle (Ag NP) arrays based on the anodic aluminum oxide (AAO) template assisted electrochemical deposition approach. The periodic nanostructure \vas optirnized to obtain high SERS activity by varying nanopore diameters and Ag NP sputtering duration to have Ag NP nanogaps in the sub 10 nm regime so that the high sensitivity was achieved with detecting R6G analytes at the 1 x 10(-10) NI level. The substrate was also used to detect TC and DCD in milk at low concentration levels of 1 X 10(-9) M and 1 X 10(-7) M, spectively, with good linear correlation between concentration and intensity (TC R-2 = 0.96; DCD R-2 = 0.99). The assignments of Raman bands of tetracycline and dicyandiamide were also given by density-functional-theory (I)FT) calculations. The advantage of this transparent SERS substrate is that it is especially useful for measurement of analytes at the interface betiveen Ag NP substrate layer and the opaque liquid containing the analytes without special pretreatment of the sample. Thus, this method may provide an alternative practical and reliable platform for rapid detection of contaminants in foods.
关键词	tetracycline (TC) dicyandiamide (DCD) surface-enhanced Raman spectroscopy (SERS) Ag nanoparticles (Ag NPs) anodic aluminum oxide (AAO) transparent substrate
DOI	10.1021/acsanm.0c01389
关键词[WOS]	LIQUID-CHROMATOGRAPHY ; SERS SUBSTRATE ; BOVINE-MILK ; RAW-MILK ; RESIDUES ; PERFORMANCE ; OXYTETRACYCLINE ; ANTIBIOTICS ; RESISTANCE ; CHLORTETRACYCLINE
收录类别	SCI
语种	英语
资助项目	National Natural Science Foundation of China[11635013] ; National Natural Science Foundation of China[11775272] ; National Natural Science Foundation of China[21904127] ; National Natural Science Foundation of China[11475217] ; Anhui Provincial Natural Science Foundation[1908085MB53]
项目资助者	National Natural Science Foundation of China ; Anhui Provincial Natural Science Foundation
WOS研究方向	Science & Technology - Other Topics ; Materials Science
WOS类目	Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary
WOS记录号	WOS:000555518200092
出版者	AMER CHEMICAL SOC
引用统计	被引频次：53[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.hfcas.ac.cn:8080/handle/334002/44891
专题	中国科学院合肥物质科学研究院
通讯作者	Huang, Qing
作者单位	1.Chinese Acad Sci, Inst Intelligent Machines, Hefei Inst Phys Sci, CAS Key Lab High Magnet Field & Ion Beam Phys Bio, Hefei 230031, Peoples R China 2.Univ Sci & Technol China, Grad Sch, Sci Isl Branch, Hefei 230026, Peoples R China 3.USDA, Environm Microbial & Food Safety Lab, ARS, Beltsville, MD 20705 USA 4.Anhui Univ, Coll Chem & Chem Engn, Hefei 230061, Peoples R China
推荐引用方式 GB/T 7714	Muhammad, Muhammad,Yan, Bin,Yao, Guohua,et al. Surface-Enhanced Raman Spectroscopy for Trace Detection of Tetracycline and Dicyandiamide in Milk Using Transparent Substrate of Ag Nanoparticle Arrays[J]. ACS APPLIED NANO MATERIALS,2020,3.
APA	Muhammad, Muhammad,Yan, Bin,Yao, Guohua,Chao, Kuanglin,Zhu, Chuhong,&Huang, Qing.(2020).Surface-Enhanced Raman Spectroscopy for Trace Detection of Tetracycline and Dicyandiamide in Milk Using Transparent Substrate of Ag Nanoparticle Arrays.ACS APPLIED NANO MATERIALS,3.
MLA	Muhammad, Muhammad,et al."Surface-Enhanced Raman Spectroscopy for Trace Detection of Tetracycline and Dicyandiamide in Milk Using Transparent Substrate of Ag Nanoparticle Arrays".ACS APPLIED NANO MATERIALS 3(2020).