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A multicenter hospital-based diagnosis study of automated breast ultrasound system in detecting breast cancer among Chinese women | |
其他题名 | A multicenter hospital-based diagnosis study of automated breast ultrasound system in detecting breast cancer among Chinese women |
2018-01-01 | |
发表期刊 | CHINESE JOURNAL OF CANCER RESEARCH |
ISSN | 1000-9604 |
摘要 | Objective: The automated breast ultrasound system (ABUS) is a potential method for breast cancer detection; however, its diagnostic performance remains unclear. We conducted a hospital-based multicenter diagnostic study to evaluate the clinical performance of the ABUS for breast cancer detection by comparing it to handheld ultrasound (HHUS) and mammography (MG). |
其他摘要 | Objective: The automated breast ultrasound system(ABUS) is a potential method for breast cancer detection;however, its diagnostic performance remains unclear. We conducted a hospital-based multicenter diagnostic study to evaluate the clinical performance of the ABUS for breast cancer detection by comparing it to handheld ultrasound(HHUS) and mammography(MG).Methods: Eligible participants underwent HHUS and ABUS testing; women aged 40–69 years additionally underwent MG. Images were interpreted using the Breast Imaging Reporting and Data System(BI-RADS).Women in the BI-RADS categories 1–2 were considered negative. Women classified as BI-RADS 3 underwent magnetic resonance imaging to distinguish true-and false-negative results. Core aspiration or surgical biopsy was performed in women classified as BI-RADS 4–5, followed by a pathological diagnosis. Kappa values and agreement rates were calculated between ABUS, HHUS and MG.Results: A total of 1,973 women were included in the final analysis. Of these, 1,353(68.6%) and 620(31.4%)were classified as BI-RADS categories 1–3 and 4–5, respectively. In the older age group, the agreement rate and Kappa value between the ABUS and HHUS were 94.0% and 0.860(P〈0.001), respectively; they were 89.2% and0.735(P〈0.001) between the ABUS and MG, respectively. Regarding consistency between imaging and pathology results, 78.6% of women classified as BI-RADS 4–5 based on the ABUS were diagnosed with precancerous lesions or cancer; which was 7.2% higher than that of women based on HHUS. For BI-RADS 1–2, the false-negative rates of the ABUS and HHUS were almost identical and were much lower than those of MG.Conclusions: We observed a good diagnostic reliability for the ABUS. Considering its performance for breast cancer detection in women with high-density breasts and its lower operator dependence, the ABUS is a promising option for breast cancer detection in China. |
关键词 | SERVICES TASK-FORCE MAMMOGRAPHIC DENSITY DIGITAL MAMMOGRAPHY RISK-FACTORS US MORTALITY UPDATE Automated breast ultrasound system breast neoplasms China |
收录类别 | CSCD |
语种 | 英语 |
资助项目 | [GE Healthcare] |
CSCD记录号 | CSCD:6249902 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.hfcas.ac.cn:8080/handle/334002/53811 |
专题 | 中国科学院合肥物质科学研究院 |
推荐引用方式 GB/T 7714 | . A multicenter hospital-based diagnosis study of automated breast ultrasound system in detecting breast cancer among Chinese women[J]. CHINESE JOURNAL OF CANCER RESEARCH,2018,30. |
APA | (2018).A multicenter hospital-based diagnosis study of automated breast ultrasound system in detecting breast cancer among Chinese women.CHINESE JOURNAL OF CANCER RESEARCH,30. |
MLA | "A multicenter hospital-based diagnosis study of automated breast ultrasound system in detecting breast cancer among Chinese women".CHINESE JOURNAL OF CANCER RESEARCH 30(2018). |
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