Anorectal malignant melanomas: Retrospective experience with surgical management

HFCAS OpenIR

	Anorectal malignant melanomas: Retrospective experience with surgical management
其他题名	Anorectal malignant melanomas: Retrospective experience with surgical management
	2011
发表期刊	WORLD JOURNAL OF GASTROENTEROLOGY
ISSN	1007-9327
摘要	AIM: To present the experience and outcomes of the surgical treatment for the patients with anorectal melanoma from the Cancer Hospital, Chinese Academy of Medical Sciences.
其他摘要	AIM: To present the experience and outcomes of the surgical treatment for the patients with anorectal melanoma from the Cancer Hospital, Chinese Academy of Medical Sciences. METHODS: Medical records of the diagnosis, surgery, and follow-up of 56 patients with anorectal melanoma who underwent surgery between 1975 and 2008 were retrospectively reviewed. The factors predictive for the survival rate of these patients were identified using multivariate analysis. RESULTS: The 5-year survival rate of the 56 patients with anorectal melanoma was 20%, 36 patients underwent abdominoperineal resection (APR) and 20 patients underwent wide local excision (WLE). The rates of local recurrence of the APR and WLE groups were 16.13% (5/36) and 68.75% (13/20), (P = 0.001), and the median survival time was 22 mo and 21 mo, respectively (P = 0.481). Univariate survival analysis demonstrated that the number of tumor and the depth of invasion had significant effects on the survival (P < 0.05). Multivariate analysis showed that the number of tumor P = 0.017, 95% confidence interval (CI) = 1.273-11.075 and the depth of invasion (P = 0.015, 95% CI = 1.249-7.591) were independent prognostic factors influencing the survival rate. CONCLUSION: Complete or RO resection is the first choice of treatment for anorectal melanoma, prognosis is poor regardless of surgical approach, and early diagnosis is the key to improved survival rate for patients with anorectal melanoma
关键词	THERAPY CANCER RESECTION PATTERNS Anorectal melanomas Prognostic factors Surgical management Survival rate
收录类别	CSCD
语种	英语
CSCD记录号	CSCD:4130860
引用统计
文献类型	期刊论文
条目标识符	http://ir.hfcas.ac.cn:8080/handle/334002/55914
专题	中国科学院合肥物质科学研究院
推荐引用方式 GB/T 7714	. Anorectal malignant melanomas: Retrospective experience with surgical management[J]. WORLD JOURNAL OF GASTROENTEROLOGY,2011,17.
APA	(2011).Anorectal malignant melanomas: Retrospective experience with surgical management.WORLD JOURNAL OF GASTROENTEROLOGY,17.
MLA	"Anorectal malignant melanomas: Retrospective experience with surgical management".WORLD JOURNAL OF GASTROENTEROLOGY 17(2011).