Risk factors related to female breast cancer in regions of Northeast China: a 1:3 matched case-control population-based study

HFCAS OpenIR

	Risk factors related to female breast cancer in regions of Northeast China: a 1:3 matched case-control population-based study
其他题名	Risk factors related to female breast cancer in regions of Northeast China: a 1:3 matched case-control population-based study
	2012
发表期刊	CHINESE MEDICAL JOURNAL
ISSN	0366-6999
摘要	Background There has been an increase in the incidence of breast cancer in China, but no definite risk and protective factors for breast cancer have been identified in Chinese females. This study was designed to identify the risk factors for female breast cancer in North and East China.
其他摘要	Background There has been an increase in the incidence of breast cancer in China, but no definite risk and protective factors for breast cancer have been identified in Chinese females. This study was designed to identify the risk factors for female breast cancer in North and East China. Methods A 1:3 matched, case-control study was conducted. All of the subjects in the case and control groups were selected from a previous epidemiological survey of 122 058 females aged 25 to 70 years. Single and multiple Logistic regression analyses were used to study potential factors in the development of breast cancer. Results Significant differences at the level of =0.20 between case and control groups were observed for the following factors: economic status, social status, family annual income, bean product consumption, body mass index (BMI), family history of breast cancer in the first or second degree, number of miscarriages, menstrual pattern, benign breast disease history, nipple leakage, inverted nipple, history of diabetes mellitus, history of hypertension, history of ovarian cyst, physical exercise, current and global quality of life satisfaction, healthy behavior and prevention, and scores of breast cancer-related knowledge. After Cox-regression model analysis (=0.10), six factors were found to be significantly related to breast cancer, of which the ORs and 95%CIs were: BMI, 1.696 (1.169C2.460, P=0.005); benign breast disease history, 2.672 (0.848C8.416, P=0.093); family history of breast cancer, 7.080 (1.758C28.551, P=0.006); number of miscarriages, 1.738 (1.014C2.978, P=0.044); global quality of life satisfaction, 3.044 (1.804C5.136, P=0.000); healthy behavior and prevention, 3.294 (1.692C6.412, P=0.000). Conclusions A comprehensive range of factors related to breast cancer was identified. Women should be educated about a healthy lifestyle, especially those with a family history of breast cancer or a personal history of benign breast disease.
关键词	HORMONE REPLACEMENT THERAPY DIABETES-MELLITUS INDUCED-ABORTION WOMENS HEALTH YOUNG-WOMEN BODY-SIZE DISEASE COHORT METAANALYSIS ASSOCIATION breast cancer female risk factor matched case-control study China
收录类别	CSCD
语种	英语
资助项目	[Clinical Department in the Hospitals of the Ministry of Health, China]
CSCD记录号	CSCD:4458965
引用统计
文献类型	期刊论文
条目标识符	http://ir.hfcas.ac.cn:8080/handle/334002/55982
专题	中国科学院合肥物质科学研究院
推荐引用方式 GB/T 7714	. Risk factors related to female breast cancer in regions of Northeast China: a 1:3 matched case-control population-based study[J]. CHINESE MEDICAL JOURNAL,2012,125.
APA	(2012).Risk factors related to female breast cancer in regions of Northeast China: a 1:3 matched case-control population-based study.CHINESE MEDICAL JOURNAL,125.
MLA	"Risk factors related to female breast cancer in regions of Northeast China: a 1:3 matched case-control population-based study".CHINESE MEDICAL JOURNAL 125(2012).