ABO blood group is a predictor of survival in patients with laryngeal cancer

HFCAS OpenIR

	ABO blood group is a predictor of survival in patients with laryngeal cancer
其他题名	ABO blood group is a predictor of survival in patients with laryngeal cancer
	2016
发表期刊	CHINESE JOURNAL OF CANCER
ISSN	1000-467X
摘要	Background: Whether the ABO blood group is associated with the survival of patients with laryngeal cancer remains unknown. The purpose of this study was to investigate the association between the ABO blood group and clinicopathologic characteristics of patients with laryngeal cancer and assess whether the ABO blood group was associated with prognosis.
其他摘要	Background Whether the ABO blood group is associated with the survival of patients with laryngeal cancer remains unknown. The purpose of this study was to investigate the association between the ABO blood group and clinicopathologic characteristics of patients with laryngeal cancer and assess whether the ABO blood group was associated with prognosis. Methods We analyzed the records of 1260 patients with laryngeal cancer who underwent curative treatment at Sun Yat-sen University Cancer Center between January 1993 and December 2009. The Chi-square test was used to assess the relationship between the ABO blood group and clinicopathologic characteristics. The Kaplan–Meier method was used to estimate 3-, 5-, and 10-year overall survival (OS) rates. The Cox proportional hazards model was used in univariate and multivariate analyses of OS. Results No significant association was found between the ABO blood group and clinicopathologic characteristics except for primary tumor site. The median OS for patients with blood groups A, B, AB, and O were 87.0, 80.0, 90.0, and 72.5months, respectively. The 3-, 5-, and 10-year OS rates were 82.4%, 76.0%, and 67.5% for patients with blood group A; 77.4%, 69.8%, and 58.4% for patients with blood group B; 82.2%, 73.1%, and 65.6% for patients with blood group AB; and 71.7%, 66.4%, and 55.5% for patients with blood group O, respectively. Univariate and multivariate analyses showed that the ABO blood group had significant effects on prognosis in patients with laryngeal cancer. Conclusions The ABO blood group is associated with survival in patients with laryngeal cancer. Patients with blood group O had significantly shorter OS than patients with other ABO blood groups.
关键词	GENOME-WIDE ASSOCIATION SQUAMOUS-CELL CARCINOMA PANCREATIC-CANCER NASOPHARYNGEAL CARCINOMA COHORT CONSORTIUM CHINESE PATIENTS GROUP ALLELES RISK POPULATION EXPRESSION The ABO blood group Laryngeal cancer Prognosis Survival
收录类别	CSCD
语种	英语
资助项目	[National Natural Science Foundation of China] ; [China International Medical Foundation] ; [Excellent Talents Project of Zhejiang Cancer Hospital, China]
CSCD记录号	CSCD:5890683
引用统计
文献类型	期刊论文
条目标识符	http://ir.hfcas.ac.cn:8080/handle/334002/56346
专题	中国科学院合肥物质科学研究院
推荐引用方式 GB/T 7714	. ABO blood group is a predictor of survival in patients with laryngeal cancer[J]. CHINESE JOURNAL OF CANCER,2016,35.
APA	(2016).ABO blood group is a predictor of survival in patients with laryngeal cancer.CHINESE JOURNAL OF CANCER,35.
MLA	"ABO blood group is a predictor of survival in patients with laryngeal cancer".CHINESE JOURNAL OF CANCER 35(2016).