Subdivision of M category for nasopharyngeal carcinoma with synchronous metastasis: time to expand the M categorization system

HFCAS OpenIR

	Subdivision of M category for nasopharyngeal carcinoma with synchronous metastasis: time to expand the M categorization system
其他题名	Subdivision of M category for nasopharyngeal carcinoma with synchronous metastasis: time to expand the M categorization system
	2015
发表期刊	CHINESE JOURNAL OF CANCER
ISSN	1000-467X
摘要	Introduction: The current metastatic category (M) of nasopharyngeal carcinoma (NPC) is a "catch-all" classification, covering a heterogeneous group of tumors ranging from potentially curable to incurable. The aim of this study was to design an M categorization system that could be applied in planning the treatment of NPC with synchronous metastasis.
其他摘要	Introduction The current metastatic category (M) of nasopharyngeal carcinoma (NPC) is a “catch-all” classification, covering a heterogeneous group of tumors ranging from potentially curable to incurable. The aim of this study was to design an M categorization system that could be applied in planning the treatment of NPC with synchronous metastasis. Methods A total of 505 NPC patients diagnosed with synchronous metastasis at Sun Yat-sen University Cancer Center between 2000 and 2009 were involved. The associations of clinical variables, metastatic features, and a proposed M categorization system with overall survival (OS) were determined by using Cox regression model. Results Multivariate analysis showed that Union for International Cancer Control (UICC) N category (N1–3 P =0.007; M1c vs. M1a, HR=2.64, 95% CI=1.75–3.98, P <0.001. Conclusions We developed an M categorization system based on the independent factors related to the prognosis of patients with metastatic NPC. This system may be helpful to further optimize individualized care for NPC patients.
关键词	PRIMARY TUMOR VOLUME EPSTEIN-BARR-VIRUS RADIOFREQUENCY ABLATION PROGNOSTIC-FACTORS RADIATION-THERAPY LIVER METASTASES STAGING SYSTEM SURVIVAL CANCER CHEMOTHERAPY Nasopharyngeal carcinoma TNM staging Metastasis Prognosis
收录类别	CSCD
语种	英语
资助项目	[National High Technology Research and Development Program of China (863 Program)]
CSCD记录号	CSCD:5545530
引用统计
文献类型	期刊论文
条目标识符	http://ir.hfcas.ac.cn:8080/handle/334002/60043
专题	中国科学院合肥物质科学研究院
推荐引用方式 GB/T 7714	. Subdivision of M category for nasopharyngeal carcinoma with synchronous metastasis: time to expand the M categorization system[J]. CHINESE JOURNAL OF CANCER,2015,34.
APA	(2015).Subdivision of M category for nasopharyngeal carcinoma with synchronous metastasis: time to expand the M categorization system.CHINESE JOURNAL OF CANCER,34.
MLA	"Subdivision of M category for nasopharyngeal carcinoma with synchronous metastasis: time to expand the M categorization system".CHINESE JOURNAL OF CANCER 34(2015).