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Long Non-coding RNAs Function as Competing Endogenous RNAs to Regulate Cancer Progression | |
其他题名 | Long Non-coding RNAs Function as Competing Endogenous RNAs to Regulate Cancer Progression |
2016 | |
发表期刊 | PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS
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ISSN | 1000-3282 |
摘要 | Long non-coding RNAs are defined as endogenous molecules With a length greater than 200 nucleotides and with no apparent coding potential. Recent studies showed that lncRNA could interact with the miRNA as a competing endogenous RNAs (ceRNAs) to participate in the expression regulation of target genes, which exert an importance role in the initiation and progression of tumor. In this review, based on lncRNA functioning as ceRNAs, we described the mechanism and function of some relevant lncRNA in the initiation and progression of tumor. A growing number of researches indicated that the interaction between lncRNA and miRNA in tumor genesis would provide new ideas in tumor diagnosis and treatment. |
关键词 | NASOPHARYNGEAL CARCINOMA HEPATOCELLULAR-CARCINOMA MESENCHYMAL TRANSITION CELL-PROLIFERATION GASTRIC-CANCER LIVER-CANCER CERNA HYPOTHESIS TUMOR-SUPPRESSOR MESSENGER-RNAS MIRNA SPONGES long non-coding RNAs (lncRNA) microRNA(miRNAs) tumorigenesis |
收录类别 | CSCD |
语种 | 英语 |
资助项目 | [National Natural Science Foundation of China] ; [Hunan Province Natural Sciences Foundation of China] |
CSCD记录号 | CSCD:5666798 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.hfcas.ac.cn:8080/handle/334002/61136 |
专题 | 中国科学院合肥物质科学研究院 |
推荐引用方式 GB/T 7714 | . Long Non-coding RNAs Function as Competing Endogenous RNAs to Regulate Cancer Progression[J]. PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS,2016,43. |
APA | (2016).Long Non-coding RNAs Function as Competing Endogenous RNAs to Regulate Cancer Progression.PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS,43. |
MLA | "Long Non-coding RNAs Function as Competing Endogenous RNAs to Regulate Cancer Progression".PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS 43(2016). |
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