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Clinicopathological features and surgical outcomes of four rare subtypes of primary liver carcinoma | |
其他题名 | Clinicopathological features and surgical outcomes of four rare subtypes of primary liver carcinoma |
2018 | |
发表期刊 | CHINESE JOURNAL OF CANCER RESEARCH |
ISSN | 1000-9604 |
摘要 | Objective: This study aimed to analyze clinicopathological and prognostic features of four rare pathological subtypes of primary liver malignancies to make better understanding of their clinical features. |
其他摘要 | Objective:This study aimed to analyze clinicopathological and prognostic features of four rare pathological subtypes of primary liver malignancies to make better understanding of their clinical features.Methods:The clinicopathological data of 114 patients who were diagnosed with histologically proven four subtypes:clear cell carcinoma(CCC),giant cell carcinoma(GCC),sarcomatoid carcinoma(SC),and combined hepatocellular-cholangiocarcinoma(CHC)between October 1998 and August 2015 were reviewed.Their survival data were compared with those of 908 patients with histologically proven common hepatocellular carcinoma(HCC)(early-and advanced-stage HCC)during the same period.Results:The outcome of the CCC group was better than that of the other three subgroups,and was similar to that of the early-stage HCC group.Also,the smallest tumor size and the highest incidence of pseudocapsule formation were observed in the CCC group.The SC group had the worst outcome among these four subgroups;the prognosis was much poorer than that of any other subgroups,even poorer than that of the advanced-stage common HCC group.No statistical difference was observed between the GCC,CHC and advanced-stage HCC groups on survival analysis.The incidences of tumor vascular emboli,TNM staging and non-radical resection were three risk factors of the prognosis.Conclusions:CCC is a low-degree malignancy and relatively favorably prognostic subtype of HCC.However,GCC,SC,and CHC are three rare high-degree malignancy subtypes of HCC with poor prognosis. |
关键词 | SARCOMATOID HEPATOCELLULAR-CARCINOMA CLEAR-CELL CARCINOMA OF-THE-LITERATURE CHOLANGIOCELLULAR CARCINOMA GIANT-CELLS CHOLANGIOCARCINOMA DIAGNOSIS SURGERY Clear cell carcinoma combined hepatocellular-cholangiocarcinoma giant cell carcinoma sarcomatoid carcinoma hepatocellular carcinoma |
收录类别 | CSCD |
语种 | 英语 |
资助项目 | [State Key Project on Infection Diseases of China] ; [National Natural Science Foundation of China] ; [National High-tech R&D (863) Program of China] ; [Capital Health Research and Development of Special] ; [CAMS Innovation Fund for Medical Sciences (CIFMS)] |
CSCD记录号 | CSCD:6269419 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.hfcas.ac.cn:8080/handle/334002/62952 |
专题 | 中国科学院合肥物质科学研究院 |
推荐引用方式 GB/T 7714 | . Clinicopathological features and surgical outcomes of four rare subtypes of primary liver carcinoma[J]. CHINESE JOURNAL OF CANCER RESEARCH,2018,30. |
APA | (2018).Clinicopathological features and surgical outcomes of four rare subtypes of primary liver carcinoma.CHINESE JOURNAL OF CANCER RESEARCH,30. |
MLA | "Clinicopathological features and surgical outcomes of four rare subtypes of primary liver carcinoma".CHINESE JOURNAL OF CANCER RESEARCH 30(2018). |
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