Clinicopathological features and surgical outcomes of four rare subtypes of primary liver carcinoma

HFCAS OpenIR

	Clinicopathological features and surgical outcomes of four rare subtypes of primary liver carcinoma
其他题名	Clinicopathological features and surgical outcomes of four rare subtypes of primary liver carcinoma
	2018
发表期刊	CHINESE JOURNAL OF CANCER RESEARCH
ISSN	1000-9604
摘要	Objective: This study aimed to analyze clinicopathological and prognostic features of four rare pathological subtypes of primary liver malignancies to make better understanding of their clinical features.
其他摘要	Objective：This study aimed to analyze clinicopathological and prognostic features of four rare pathological subtypes of primary liver malignancies to make better understanding of their clinical features.Methods：The clinicopathological data of 114 patients who were diagnosed with histologically proven four subtypes：clear cell carcinoma（CCC）,giant cell carcinoma（GCC）,sarcomatoid carcinoma（SC）,and combined hepatocellular-cholangiocarcinoma（CHC）between October 1998 and August 2015 were reviewed.Their survival data were compared with those of 908 patients with histologically proven common hepatocellular carcinoma（HCC）（early-and advanced-stage HCC）during the same period.Results：The outcome of the CCC group was better than that of the other three subgroups,and was similar to that of the early-stage HCC group.Also,the smallest tumor size and the highest incidence of pseudocapsule formation were observed in the CCC group.The SC group had the worst outcome among these four subgroups;the prognosis was much poorer than that of any other subgroups,even poorer than that of the advanced-stage common HCC group.No statistical difference was observed between the GCC,CHC and advanced-stage HCC groups on survival analysis.The incidences of tumor vascular emboli,TNM staging and non-radical resection were three risk factors of the prognosis.Conclusions：CCC is a low-degree malignancy and relatively favorably prognostic subtype of HCC.However,GCC,SC,and CHC are three rare high-degree malignancy subtypes of HCC with poor prognosis.
关键词	SARCOMATOID HEPATOCELLULAR-CARCINOMA CLEAR-CELL CARCINOMA OF-THE-LITERATURE CHOLANGIOCELLULAR CARCINOMA GIANT-CELLS CHOLANGIOCARCINOMA DIAGNOSIS SURGERY Clear cell carcinoma combined hepatocellular-cholangiocarcinoma giant cell carcinoma sarcomatoid carcinoma hepatocellular carcinoma
收录类别	CSCD
语种	英语
资助项目	[State Key Project on Infection Diseases of China] ; [National Natural Science Foundation of China] ; [National High-tech R&D (863) Program of China] ; [Capital Health Research and Development of Special] ; [CAMS Innovation Fund for Medical Sciences (CIFMS)]
CSCD记录号	CSCD:6269419
引用统计
文献类型	期刊论文
条目标识符	http://ir.hfcas.ac.cn:8080/handle/334002/62952
专题	中国科学院合肥物质科学研究院
推荐引用方式 GB/T 7714	. Clinicopathological features and surgical outcomes of four rare subtypes of primary liver carcinoma[J]. CHINESE JOURNAL OF CANCER RESEARCH,2018,30.
APA	(2018).Clinicopathological features and surgical outcomes of four rare subtypes of primary liver carcinoma.CHINESE JOURNAL OF CANCER RESEARCH,30.
MLA	"Clinicopathological features and surgical outcomes of four rare subtypes of primary liver carcinoma".CHINESE JOURNAL OF CANCER RESEARCH 30(2018).