The Role and Mechanism of PVT1 in Promoting Human Cancer Progression

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	The Role and Mechanism of PVT1 in Promoting Human Cancer Progression
其他题名	The Role and Mechanism of PVT1 in Promoting Human Cancer Progression
	2017
发表期刊	PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS
ISSN	1000-3282
摘要	In recent years, long non-coding RNA is found to play an important role in the regulation of cell growth, differentiation and other biological functions, and is closely related to the occurrence and development of cancer. The long non-coding RNA gene, PVT1, located in the fragile chromosome 8q24 region has been widely concerned. LncRNA PVT1 is highly expresses in many types of cancer, and act as potential oncogene. It is commonly to form new fusion gene by chromosome break, and translocation, and regulation of tumor cell function; it also interact with MYC and participate in tumor cell proliferation, apoptosis by multiple pathways. However, the specific molecular mechanisms that occur in the development of cancer still need further research. In this paper, we summarized the features, functions and roles of PVT1 in human cancer.
关键词	LONG NONCODING RNA SQUAMOUS-CELL CARCINOMA C-MYC ONCOGENE POOR-PROGNOSIS GASTRIC-CANCER NASOPHARYNGEAL CARCINOMA BREAST-CANCER LUNG-CANCER EPIGENETIC REGULATION INCREASED EXPRESSION cancer long non-coding RNA PVT1 MYC
收录类别	CSCD
语种	英语
资助项目	[National Natural Science Foundation of China] ; [Hunan Province Natural Sciences Foundation of China]
CSCD记录号	CSCD:6110323
引用统计
文献类型	期刊论文
条目标识符	http://ir.hfcas.ac.cn:8080/handle/334002/64964
专题	中国科学院合肥物质科学研究院
推荐引用方式 GB/T 7714	. The Role and Mechanism of PVT1 in Promoting Human Cancer Progression[J]. PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS,2017,44.
APA	(2017).The Role and Mechanism of PVT1 in Promoting Human Cancer Progression.PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS,44.
MLA	"The Role and Mechanism of PVT1 in Promoting Human Cancer Progression".PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS 44(2017).