Clinicopathological Characteristics and Prognosis of Colorectal Cancer in Chinese Adolescent Patients

HFCAS OpenIR

	Clinicopathological Characteristics and Prognosis of Colorectal Cancer in Chinese Adolescent Patients
其他题名	Clinicopathological Characteristics and Prognosis of Colorectal Cancer in Chinese Adolescent Patients
	2015
发表期刊	CHINESE MEDICAL JOURNAL
ISSN	0366-6999
摘要	Background: Colorectal adenocarcinoma rarely occurred in adolescent. Clinical feature and prognosis of this population are not clear until now. In addition, DNA mismatch repair (MMR) status may relate to the early disease occurrence. The present study aimed to perform a retrospective analysis of adolescent patients with colorectal cancer, including clinicopathological characteristics and prognosis.
其他摘要	Background: Colorectal adenocarcinoma rarely occurred in adolescent. Clinical feature and prognosis of this population are not clear until now. In addition, DNA mismatch repair (MMR) status may relate to the early disease occurrence. The present study aimed to perform a retrospective analysis of adolescent patients with colorectal cancer, including clinicopathological characteristics and prognosis. Methods: The medical records of 11,503 patients diagnosed as colorectal cancer in Cancer Hospital, Chinese Academy of Medical Sciences from January 1999 to December 2009 were retrospectively reviewed. Finally, 19 patients who were between 10 and 20 years old were selected as the study group. We summarized the clinicopathological characteristics, analyzed the association with prognosis and assessed the expression of MMR protein by immunohistochemical method. Results: The most common primary site was the right colon in 7 patients. Ten patients had Stage III colorectal cancer, 5 patients had Stage IV disease. Signet ring cell carcinoma was the most frequent pathological type (7 P = 0.02). Conclusions: Colorectal cancer in Chinese adolescents was very rare. The chinese adolecents with colorectal cancer were frequently diagnosed in the right colon, as Stage III
关键词	MUCINOUS CARCINOMA YOUNG-PATIENTS COLON RECTUM Adolescence Colorectal Cancer Prognosis
收录类别	CSCD
语种	英语
CSCD记录号	CSCD:5583912
引用统计
文献类型	期刊论文
条目标识符	http://ir.hfcas.ac.cn:8080/handle/334002/68991
专题	中国科学院合肥物质科学研究院
推荐引用方式 GB/T 7714	. Clinicopathological Characteristics and Prognosis of Colorectal Cancer in Chinese Adolescent Patients[J]. CHINESE MEDICAL JOURNAL,2015,128.
APA	(2015).Clinicopathological Characteristics and Prognosis of Colorectal Cancer in Chinese Adolescent Patients.CHINESE MEDICAL JOURNAL,128.
MLA	"Clinicopathological Characteristics and Prognosis of Colorectal Cancer in Chinese Adolescent Patients".CHINESE MEDICAL JOURNAL 128(2015).