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Efficient Detection of Pre-Proinsulin by Double Antibody Sandwich ELISA 期刊论文
APPLIED SCIENCES-BASEL, 2022, 卷号: 12
作者:  Zhu, Zhu;  Wang, Han;  Wang, Li;  Wei, Zhou;  Zheng, Zhiming;  Wang, Peng
收藏  |  浏览/下载：51/0  |  提交时间：2022/12/22
recombinant human insulin  pre-proinsulin  monoclonal antibody  sandwich ELISA  
Rational Design by Structural Biology of Industrializable, Long-Acting Antihyperglycemic GLP-1 Receptor Agonists 期刊论文
PHARMACEUTICALS, 2022, 卷号: 15
作者:  Sun, Lei;  Zheng, Zhi-Ming;  Shao, Chang-Sheng;  Zhang, Zhi-Yong;  Li, Ming-Wei;  Wang, Li;  Wang, Han;  Zhao, Gen-Hai;  Wang, Peng
收藏  |  浏览/下载：48/0  |  提交时间：2022/12/22
glucagon-like peptide-1  GLP-1 receptor agonist  functional protein design  molecular dynamics simulation  long-acting antihyperglycemic  
Bottom-up synthetic biology approach for improving the efficiency of menaquinone-7 synthesis in Bacillus subtilis 期刊论文
Microbial Cell Factories, 2022, 卷号: 21
作者:  Ding,Xiumin;  Zheng,Zhiming;  Zhao,Genhai;  Wang,Li;  Wang,Han;  Yang,Qiang;  Zhang,Mengxue;  Li,Luyao;  Wang,Peng
收藏  |  浏览/下载：34/0  |  提交时间：2022/12/22
Menaquinone-7  Bacillus subtilis  Synthetic biology  Metabolic engineering  Cofactor engineering  NADH kinase  
Vitamin K2 Modulates Mitochondrial Dysfunction Induced by 6-Hydroxydopamine in SH-SY5Y Cells via Mitochondrial Quality-Control Loop 期刊论文
NUTRIENTS, 2022, 卷号: 14
作者:  Tang, Hengfang;  Zheng, Zhiming;  Wang, Han;  Wang, Li;  Zhao, Genhai;  Wang, Peng
收藏  |  浏览/下载：59/0  |  提交时间：2022/05/16
vitamin K2  apoptosis  ROS  mitochondrial dysfunction  mitophagy  mitochondrial biogenesis  mitochondrial quality-control loop  PINK1  Parkin signaling pathway  
Engineering microbial consortia of Elizabethkingia meningoseptica and Escherichia coli strains for the biosynthesis of vitamin K2 期刊论文
Microbial Cell Factories, 2022, 卷号: 21
作者:  Yang,Qiang;  Zheng,Zhiming;  Zhao,Genhai;  Wang,Li;  Wang,Han;  Ding,XiuMin;  Jiang,Chunxu;  Li,Chu;  Ma,Guoliang;  Wang,Peng
收藏  |  浏览/下载：76/0  |  提交时间：2022/05/16
Vitamin K2  Microbial consortia  Metabolic engineering  Elizabethkingia meningoseptica  
Cloning and functional characterization of the geranylgeranyl diphosphate synthase(GGPPS)from Elizabethkingia meningoseptica sp.F2 期刊论文
PROTEIN EXPRESSION AND PURIFICATION, 2022, 卷号: 189
作者:  Yang, Qiang;  Zheng, Zhiming;  Zhao, Genhai;  Wang, Li;  Wang, Han;  Ni, Wenfeng;  Sun, Xiaowen;  Zhang, Mengxue;  Tang, Hengfang;  Wang, Peng
收藏  |  浏览/下载：63/0  |  提交时间：2021/11/29
Elizabethkingia meningoseptica  Geranylgeranyl diphosphate synthase  Soluble expression  MK-4  
纳豆芽孢杆菌men基因过表达菌株的构建及提高溶氧强化MK-7合成 期刊论文
应用与环境生物学报, 2022, 卷号: 28
作者:  李楚;  王晗;  王丽;  王鹏;  郑之明
收藏  |  浏览/下载：23/0  |  提交时间：2023/11/10
Bacillus subtilis natto  Sipizizen transformation optimization  menadione pathway  overexpression vector construction  men gene  纳豆芽孢杆菌  Sipizizen转化法优化  甲萘醌途径  过表达载体构建  men基因  
Gradient radiation breeding and culture domestication of menaquinone producing strains 期刊论文
BIOPROCESS AND BIOSYSTEMS ENGINEERING, 2021
作者:  Wu, Hefang;  Wang, Han;  Wang, Peng;  Zhao, Geihai;  Liu, Hui;  Wang, Li;  Sun, Xiaowen;  Zheng, Zhiming
收藏  |  浏览/下载：47/0  |  提交时间：2021/06/15
Biofilm lipid peroxidation  Gamma ray mutagenesis  Low-energy ion implantation  Menaquinone (MK)  SOD activity  
A study of hydrophobins-modified menaquinone-7 on osteoblastic cells differentiation 期刊论文
MOLECULAR AND CELLULAR BIOCHEMISTRY, 2021
作者:  Tang, Hengfang;  Zhu, Zhu;  Zheng, Zhiming;  Wang, Han;  Li, Chu;  Wang, Li;  Zhao, Genhai;  Wang, Peng
收藏  |  浏览/下载：53/0  |  提交时间：2021/03/15
Menaquinone-7  Hydrophobins  Alkaline phosphatase  Osteocalcin  OPG  RANKL  Mitochondria  
A simple and efficient method for the extraction and separation of menaquinone homologs from wet biomass of Flavobacterium 期刊论文
BIOPROCESS AND BIOSYSTEMS ENGINEERING, 2018, 卷号: 41, 期号: 1, 页码: 107-113
作者:  Wei, Hongfei;  Zhao, Genhai;  Liu, Hui;  Wang, Han;  Ni, Wenfeng;  Wang, Peng;  Zheng, Zhiming
浏览  |  Adobe PDF(1238Kb)  |  收藏  |  浏览/下载：193/74  |  提交时间：2019/02/28
Wet cell extraction  Separation  Menaquinone homologs  Flavobacterium