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Design, synthesis and biological evaluation of sulfonamides inhibitors of XPO1 displaying activity against multiple myeloma cells 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 235
作者:  Qu, Bingxue;  Xu, Yongjin;  Lu, Yang;  Zhuang, Weihao;  Jin, Xinxin;  Shi, Qiuqiu;  Yan, Shike;  Guo, Yu;  Shen, Zheyuan;  Che, Jinxin;  Wu, Yize;  Tong, Lexian;  Dong, Xiaowu;  Yang, Haiyan
收藏  |  浏览/下载：31/0  |  提交时间：2022/12/23
XPO1  Multiple myeloma  MM.1S  N-phenylsulfonamide  Oral administration  
CDK9 inhibitors in cancer research 期刊论文
RSC MEDICINAL CHEMISTRY, 2022
作者:  Huang, Zhi;  Wang, Tianqi;  Wang, Cheng;  Fan, Yan
收藏  |  浏览/下载：39/0  |  提交时间：2022/12/23
JQ1 synergizes with the Bcl-2 inhibitor ABT-263 against MYCN-amplified small cell lung cancer 期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 49, 页码: 86312-86324
作者:  Wang, Huogang;  Hong, Bo;  Li, Xuemin;  Deng, Ke;  Li, Hong;  Lui, Vivian Wai Yan;  Lin, Wenchu
浏览  |  Adobe PDF(9738Kb)  |  收藏  |  浏览/下载：97/40  |  提交时间：2018/08/17
Small Cell Lung Cancer  N-myc  Bcl-2  Jq1  Abt-263  
EpCAM Inhibition Sensitizes Chemoresistant Leukemia to Immune Surveillance 期刊论文
CANCER RESEARCH, 2017, 卷号: 77, 期号: 2, 页码: 482-493
作者:  Zheng, Xiaohu;  Fan, Xiaolei;  Fu, Binqing;  Zheng, Meijuan;  Zhang, Aimei;  Zhong, Kai;  Yan, Jialai;  Sun, Rui;  Tian, Zhigang;  Wei, Haiming
浏览  |  Adobe PDF(2088Kb)  |  收藏  |  浏览/下载：186/146  |  提交时间：2018/07/04
Ibrutinib targets mutant-EGFR kinase with a distinct binding conformation 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 43, 页码: 69760-69769
作者:  Wang, Aoli;  Yan, Xiao-E;  Wu, Hong;  Wang, Wenchao;  Hu, Chen;  Chen, Cheng;  Zhao, Zheng;  Zhao, Peng;  Li, Xixiang;  Wang, Li;  Wang, Beilei;  Ye, Zi;  Wang, Jinhua;  Wang, Chu;  Zhang, Wei;  Gray, Nathanael S.;  Weisberg, Ellen L.;  Chen, Liang;  Liu, Jing;  Yun, Cai-Hong;  Liu, Qingsong
浏览  |  Adobe PDF(2026Kb)  |  收藏  |  浏览/下载：124/63  |  提交时间：2017/11/21
Ibrutinib  Egfr Kinase  Dfg-in/c-helix-out  Inactive Conformation  Nsclc  
Characterization of selective and potent PI3K delta inhibitor (PI3KD-IN-015) for B-Cell malignances 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 22, 页码: 32641-32651
作者:  Liu, Xiaochuan;  Wang, Aoli;  Liang, Xiaofei;  Chen, Cheng;  Liu, Juanjuan;  Zhao, Zheng;  Wu, Hong;  Deng, Yuanxin;  Wang, Li;  Wang, Beilei;  Wu, Jiaxin;  Liu, Feiyang;  Fernandes, Stacey M.;  Adamia, Sophia;  Stone, Richard M.;  Galinsky, Ilene A.;  Brown, Jennifer R.;  Griffin, James D.;  Zhang, Shanchun;  Loh, Teckpeng;  Zhang, Xin;  Wang, Wenchao;  Weisberg, Ellen L.;  Liu, Jing;  Liu, Qingsong
浏览  |  Adobe PDF(5138Kb)  |  收藏  |  浏览/下载：84/29  |  提交时间：2017/11/16
Pi3k Delta  Leukemia  B-cell Malignances  Pi3k  Kinase Inhibitors  
Discovery of N-(34(1-lsonicotinoylpiperidin-4-yl)oxy)-4methylpheny1)-3-(trifluoromethyl)benzamide (CHMFL-KIT-110) as a Selective, Potent, and Orally Available Type II c-KIT Kinase Inhibitor for Gastrointestinal Stromal Tumors (GISTs) 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 8, 页码: 3964-3979
作者:  Wang, Qang;  Liu, Feiyang;  Wang, Beilei;  Zou, Fengming;  Chen, Cheng;  Liu, Xiaochuan;  Wang, Aoli;  Qi, Shuang;  Wang, Wenchao;  Qi, Ziping;  Zhao, Zheng;  Hu, Zhenquan;  Wang, Wei;  Wang, Li;  Zhang, Shanchun;  Wang, Yuexiang;  Liu, Jing;  Liu, Qingsong
浏览  |  Adobe PDF(10221Kb)  |  收藏  |  浏览/下载：128/75  |  提交时间：2017/11/10
Ibrutinib selectively targets FLT3-ITD in mutant FLT3-positive AML 期刊论文
LEUKEMIA, 2016, 卷号: 30, 期号: 3, 页码: 754-757
作者:  Wu, H.;  Hu, C.;  Wang, A.;  Weisberg, E. L.;  Wang, W.;  Chen, C.;  Zhao, Z.;  Yu, K.;  Liu, J.;  Wu, J.;  Nonami, A.;  Wang, L.;  Wang, B.;  Stone, R. M.;  Liu, S.;  Griffin, J. D.;  Liu, J.;  Liu, Q.
浏览  |  Adobe PDF(422Kb)  |  收藏  |  浏览/下载：140/79  |  提交时间：2017/11/06
Discovery of a BTK/MNK dual inhibitor for lymphoma and leukemia 期刊论文
LEUKEMIA, 2016, 卷号: 30, 期号: 1, 页码: 173-181
作者:  Wu, H.;  Hu, C.;  Wang, A.;  Weisberg, E. L.;  Chen, Y.;  Yun, C-H;  Wang, W.;  Liu, Y.;  Liu, X.;  Tian, B.;  Wang, J.;  Zhao, Z.;  Liang, Y.;  Li, B.;  Wang, L.;  Wang, B.;  Chen, C.;  Buhrlage, S. J.;  Qi, Z.;  Zou, F.;  Nonami, A.;  Li, Y.;  Fernandes, S. M.;  Adamia, S.;  Stone, R. M.;  Galinsky, I. A.;  Wang, X.;  Yang, G.;  Griffin, J. D.;  Brown, J. R.;  Eck, M. J.;  Liu, J.;  Gray, N. S.;  Liu, Q.
浏览  |  Adobe PDF(2065Kb)  |  收藏  |  浏览/下载：142/43  |  提交时间：2017/10/27