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Discovery of (E)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)propanamide (CHMFL-ABL-121) as a highly potent ABL kinase inhibitor capable of overcoming a variety of ABL mutants including T315I for chronic myeloid leukemia 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 160, 页码: 61-81
作者:  Liu, Xuesong;  Wang, Beilei;  Chen, Cheng;  Jiang, Zongru;  Hu, Chen;  Wu, Hong;  Zhang, Yicong;  Liu, Xiaochuan;  Wang, Wenliang;  Wang, Junjie;  Hu, Zhenquan;  Wang, Aoli;  Huang, Tao;  Liu, Qingwang;  Wang, Wei;  Wang, Li;  Wang, Wenchao;  Ren, Tao;  Li, Lili;  Xia, Ruixiang;  Ge, Jian;  Liu, Qingsong;  Liu, Jing
Adobe PDF(4593Kb)  |  收藏  |  浏览/下载：198/104  |  提交时间：2019/01/11
ABL kinase  Kinase inhibitor  ABL mutant  CML  
Velocity-space sensitivity of the compact neutron emission spectrometers at EAST 期刊论文
REVIEW OF SCIENTIFIC INSTRUMENTS, 2018, 卷号: 89, 期号: 10, 页码: 4
作者:  Zhang, Y. M.;  Ge, L. J.;  Sun, J. Q.;  Hu, Z. M.;  Nocente, M.;  Gorini, G.;  Tardocchi, M.;  Zhong, G. Q.;  Hu, L. Q.;  Li, X. Q.;  Fan, T. S.
Adobe PDF(1013Kb)  |  收藏  |  浏览/下载：114/51  |  提交时间：2019/01/11