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Kinases Involved in Both Autophagy and Mitosis 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2017, 卷号: 18, 期号: 9, 页码: 1-15
作者:  Li, Zhiyuan;  Zhang, Xin
浏览  |  Adobe PDF(277Kb)  |  收藏  |  浏览/下载：109/50  |  提交时间：2018/08/17
Kinases  Autophagy  Mitosis  Cyclin-dependent Kinases  Aurora  Polo-like Kinases  
Discovery of N-((1-(4-(3-(3-((6,7-Dimethoxyquinolin-3-yl)oxy)phenyl)ureido)-2-(trifluoromethyl)phenyl)piperidin-4-yl)methyl)propionamide (CHMFL-KIT-8140) as a Highly Potent Type II Inhibitor Capable of Inhibiting the T670I "Gatekeeper" Mutant of cKIT Kinase 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 18, 页码: 8456-8472
作者:  Li, Binhua;  Wang, Aoli;  Liu, Juan;  Qi, Ziping;  Liu, Xiaochuan;  Yu, Kailin;  Wu, Hong;  Chen, Cheng;  Hu, Chen;  Wang, Wenchao;  Wu, Jiaxin;  Hu, Zhenquan;  Ye, Ling;  Zou, Fengming;  Liu, Feiyang;  Wang, Beilei;  Wang, Li;  Ren, Tao;  Zhang, Shaojuan;  Bai, Mingfeng;  Zhang, Shanchun;  Liu, Jing;  Liu, Qingsong
浏览  |  Adobe PDF(2856Kb)  |  收藏  |  浏览/下载：1409/1299  |  提交时间：2017/11/21
Discovery of N-(34(1-lsonicotinoylpiperidin-4-yl)oxy)-4methylpheny1)-3-(trifluoromethyl)benzamide (CHMFL-KIT-110) as a Selective, Potent, and Orally Available Type II c-KIT Kinase Inhibitor for Gastrointestinal Stromal Tumors (GISTs) 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 8, 页码: 3964-3979
作者:  Wang, Qang;  Liu, Feiyang;  Wang, Beilei;  Zou, Fengming;  Chen, Cheng;  Liu, Xiaochuan;  Wang, Aoli;  Qi, Shuang;  Wang, Wenchao;  Qi, Ziping;  Zhao, Zheng;  Hu, Zhenquan;  Wang, Wei;  Wang, Li;  Zhang, Shanchun;  Wang, Yuexiang;  Liu, Jing;  Liu, Qingsong
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Discovery of a BTK/MNK dual inhibitor for lymphoma and leukemia 期刊论文
LEUKEMIA, 2016, 卷号: 30, 期号: 1, 页码: 173-181
作者:  Wu, H.;  Hu, C.;  Wang, A.;  Weisberg, E. L.;  Chen, Y.;  Yun, C-H;  Wang, W.;  Liu, Y.;  Liu, X.;  Tian, B.;  Wang, J.;  Zhao, Z.;  Liang, Y.;  Li, B.;  Wang, L.;  Wang, B.;  Chen, C.;  Buhrlage, S. J.;  Qi, Z.;  Zou, F.;  Nonami, A.;  Li, Y.;  Fernandes, S. M.;  Adamia, S.;  Stone, R. M.;  Galinsky, I. A.;  Wang, X.;  Yang, G.;  Griffin, J. D.;  Brown, J. R.;  Eck, M. J.;  Liu, J.;  Gray, N. S.;  Liu, Q.
浏览  |  Adobe PDF(2065Kb)  |  收藏  |  浏览/下载：142/43  |  提交时间：2017/10/27