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Darinaparsin (ZIO-101) enhances the sensitivity of small-cell lung cancer to PARP inhibitors 期刊论文
ACTA PHARMACOLOGICA SINICA, 2022
作者:  Cao, Guo-Zhen;  Ma, Li-Ying;  Zhang, Zong-Hui;  Wang, Xiao-Lin;  Hua, Jing-Han;  Zhang, Jia-Hui;  Lv, Yang;  Zhang, Shao-Bo;  Ou, Jian;  Lin, Wen-Chu
收藏  |  浏览/下载：48/0  |  提交时间：2022/12/22
small-cell lung cancer  H3  3  PARP1  PARP inhibitor  darinaparsin  combination treatment  
Comprehensive analysis of the expression, prognosis, and immune infiltrates for CHDs in human lung cancer 期刊论文
DISCOVER ONCOLOGY, 2022, 卷号: 13
作者:  Lv, Yang;  Lin, Wenchu
收藏  |  浏览/下载：39/0  |  提交时间：2022/12/23
Lung cancer  CHD family  Prognosis  Bioinformatics analysis  Immune infiltrates  
BRD4 Targets the KEAP1-Nrf2-G6PD Axis and Suppresses Redox Metabolism in Small Cell Lung Cancer 期刊论文
ANTIOXIDANTS, 2022, 卷号: 11
作者:  Lv, Yang;  Lv, Xiaotong;  Zhang, Jiahui;  Cao, Guozhen;  Xu, Changzhi;  Zhang, Buchang;  Lin, Wenchu
收藏  |  浏览/下载：51/0  |  提交时间：2022/05/16
small cell lung cancer  BRD4  KEAP1  Nrf2  pentose phosphate pathway  
FK228 potentiates topotecan activity against small cell lung cancer cells via induction of SLFN11 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021
作者:  Yin, Yan-ping;  Ma, Li-ying;  Cao, Guo-zhen;  Hua, Jing-han;  Lv, Xiao-tong;  Lin, Wen-chu
收藏  |  浏览/下载：71/0  |  提交时间：2022/01/10
small cell lung cancer  topotecan  DNA damage response  FK228  SLFN11  methylation  epigenetic modulation  
Exosomal miR-92b-3p Promotes Chemoresistance of Small Cell Lung Cancer Through the PTEN/AKT Pathway 期刊论文
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2021, 卷号: 9
作者:  Li, Ming;  Shan, Wulin;  Hua, Yan;  Chao, Fengmei;  Cui, Yayun;  Lv, Lei;  Dou, Xiaoyan;  Bian, Xing;  Zou, Jinglu;  Li, Hong;  Lin, Wenchu
收藏  |  浏览/下载：54/0  |  提交时间：2021/08/31
exosome  miR-92b-3p  small cell lung cancer  chemoresistance  migration  
FK228 sensitizes radioresistant small cell lung cancer cells to radiation 期刊论文
CLINICAL EPIGENETICS, 2021, 卷号: 13
作者:  Li, Hong;  Ma, Liying;  Bian, Xing;  Lv, Yang;  Lin, Wenchu
收藏  |  浏览/下载：44/0  |  提交时间：2021/04/26
Small cell lung cancer  FK228  Histone deacetylase  PI3K  Radioresistance  DNA damage repair  
Combinations of proteasome inhibitors with obatoclax are effective for small cell lung cancer 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020
作者:  Yin, Yan-ping;  Shi, Wen-hao;  Deng, Ke;  Liu, Xiao-li;  Li, Hong;  Lv, Xiao-tong;  Lui, Vivian Wai Yan;  Ding, Chen;  Hong, Bo;  Lin, Wen-chu
收藏  |  浏览/下载：61/0  |  提交时间：2020/12/28
small cell lung cancer  obatoclax  bortezomib  carfilzomib  MCL-1  apoptosis  FOXM1  proteomics analysis  
The dual HDAC-PI3K inhibitor CUDC-907 displays single-agent activity and synergizes with PARP inhibitor olaparib in small cell lung cancer 期刊论文
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2020, 卷号: 39
作者:  Ma, Liying;  Bian, Xing;  Lin, Wenchu
收藏  |  浏览/下载：85/0  |  提交时间：2020/11/30
SCLC  PI3K  HDAC  CUDC-907  PARP1  Olaparib  DSB repair  Combination treatment  
Circulating miR-92b and miR-375 for monitoring the chemoresistance and prognosis of small cell lung cancer 期刊论文
SCIENTIFIC REPORTS, 2020, 卷号: 10
作者:  Li, Ming;  Shan, Wulin;  Hong, Bo;  Zou, Jinglu;  Li, Hong;  Han, Dandan;  Zhang, Yang;  Li, Lailing;  Li, Dan;  Lin, Wenchu
收藏  |  浏览/下载：37/0  |  提交时间：2020/10/26
Osimertinib successfully combats EGFR-negative glioblastoma cells by inhibiting the MAPK pathway 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020
作者:  Chen, Cheng;  Cheng, Chuan-dong;  Wu, Hong;  Wang, Zuo-wei;  Wang, Li;  Jiang, Zong-ru;  Wang, Ao-li;  Hu, Chen;  Dong, Yong-fei;  Niu, Wan-xiang;  Qi, Shuang;  Qi, Zi-ping;  Liu, Jing;  Wang, Wen-chao;  Niu, Chao-shi;  Liu, Qing-song
浏览  |  Adobe PDF(3476Kb)  |  收藏  |  浏览/下载：101/36  |  提交时间：2020/11/26
glioblastoma  osimertinib  temozolamide  MAPK-signaling pathway  MNK  eukaryotic translation initiation factor 4E