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Predicting and overcoming resistance to CDK9 inhibitors for cancer therapy 期刊论文
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13
作者:  Hua, Chen;  Shena, Lijuan;  Zoua, Fengming;  Wua, Yun;  Wanga, Beilei;  Wanga, Aoli;  Wud, Chao;  Wanga, Li;  Liua, Jing;  Wanga, Wenchao;  Liua, Qingsong
收藏  |  浏览/下载：39/0  |  提交时间：2023/11/10
Acquired resistance mutations  CDK9 inhibitors  Transcription  Single nucleotide polymorphisms  BAY1251152  
S3I-201 derivative incorporating naphthoquinone unit as effective STAT3 inhibitors: Design, synthesis and anti-gastric cancer evaluation 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2022, 卷号: 71
作者:  Li, Haobin;  Cai, Maohua;  Cao, Fei;  Yu, Dehua;  Yang, Jing;  Yu, Wenkai;  Chu, Chu;  Guan, Xiaoqing;  Qin, Jiang-Jiang;  Dong, Jinyun
收藏  |  浏览/下载：44/0  |  提交时间：2022/12/22
STAT3 inhibitor  Quinone derivative  S3I-201  Anti -gastric cancer drug  
Recent Update on Development of Small-Molecule STAT3 Inhibitors for Cancer Therapy: From Phosphorylation Inhibition to Protein Degradation 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64
作者:  Dong, Jinyun;  Cheng, Xiang-Dong;  Zhang, Wei-Dong;  Qin, Jiang-Jiang
收藏  |  浏览/下载：59/0  |  提交时间：2021/08/31
PROTAC: An Effective Targeted Protein Degradation Strategy for Cancer Therapy 期刊论文
FRONTIERS IN PHARMACOLOGY, 2021, 卷号: 12
作者:  Qi, Si-Min;  Dong, Jinyun;  Xu, Zhi-Yuan;  Cheng, Xiang-Dong;  Zhang, Wei-Dong;  Qin, Jiang-Jiang
收藏  |  浏览/下载：52/0  |  提交时间：2021/06/15
PROTAC  E3 ubiquitin ligase  protein degradation  ubiquitin-proteasome system  cancer therapy  
Targeting lactate dehydrogenase a improves radiotherapy efficacy in non-small cell lung cancer: from bedside to bench 期刊论文
JOURNAL OF TRANSLATIONAL MEDICINE, 2021, 卷号: 19
作者:  Yang, Yang;  Chong, Yu;  Chen, Mengyuan;  Dai, Wumin;  Zhou, Xia;  Ji, Yongling;  Qiu, Guoqin;  Du, Xianghui
收藏  |  浏览/下载：63/0  |  提交时间：2021/06/15
LDHA  NSCLC  Radiosensitivity  DNA repair  ROS  Apoptosis  
Towards customized cancer vaccines: a promising filed in personalized cancer medicine 期刊论文
EXPERT REVIEW OF VACCINES, 2021
作者:  Xu, Xiaoling;  Zhou, Zichao;  Li, Hui;  Fan, Yun
收藏  |  浏览/下载：41/0  |  提交时间：2021/05/17
Cancer vaccines  tumor  neoantigens  personalized treatment  mutations  
Adverse events associated with nilotinib in chronic myeloid leukemia: mechanisms and management strategies 期刊论文
EXPERT REVIEW OF CLINICAL PHARMACOLOGY, 2021
作者:  Wang, Zeng;  Jiang, Liyu;  Yan, Hao;  Xu, Zhifei;  Luo, Peihua
收藏  |  浏览/下载：61/0  |  提交时间：2021/04/26
Adverse events  chronic myeloid leukemia  management  mechanisms  molecular target  nilotinib  
Optimal induction chemotherapeutic regimen followed by concurrent chemotherapy plus intensity-modulated radiotherapy as first-line therapy for locoregionally advanced nasopharyngeal carcinoma 期刊论文
MEDICINE, 2020, 卷号: 99
作者:  Wang, Fangzheng;  Jiang Chuner;  Wang Lei;  Yan Fengqin;  Ye Zhimin;  Sun Quanquan;  Liu Tongxin;  Fu Zhenfu;  Jiang Yangming
收藏  |  浏览/下载：65/0  |  提交时间：2020/11/30
concurrent chemotherapy  induction chemotherapy  intensity-modulated radiotherapy  nasopharyngeal carcinoma  prognosis  toxicity  
Impact of Radiation Dose on Survival for Esophageal Squamous Cell Carcinoma Treated With Neoadjuvant Chemoradiotherapy 期刊论文
FRONTIERS IN ONCOLOGY, 2020, 卷号: 10
作者:  Yang, Yang;  Xu, Xiaofang;  Zhou, Xia;  Bao, Wuan;  Zhang, Danhong;  Gu, Feiying;  Du, Xianghui;  Chen, Qixun;  Qiu, Guoqin
收藏  |  浏览/下载：26/0  |  提交时间：2020/10/26
esophageal cancer  neoadjuvant chemoradiotherapy  surgery  radiation dose  trimodality cancer treatment  
Quasi-Round HTS Conductor Using REBCO Tapes for Fusion Magnet Application 期刊论文
IEEE TRANSACTIONS ON APPLIED SUPERCONDUCTIVITY, 2020
作者:  Shi, Yi;  Liu, Fang;  Liu, Huajun;  Tan, Yunfei;  Zhang, Xingtao;  Jin, Huan;  Yu, Ming;  Lei, Lei;  Guo, Liang
浏览  |  Adobe PDF(1860Kb)  |  收藏  |  浏览/下载：123/46  |  提交时间：2020/10/26
Coated conductor (CC)  high-temperature superconductor (HTS) cable  round strand  stacked cable