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HFCAS OpenIR
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Discovery of 2-(4-Chloro-3-(trifluoromethyl)phenyl)-N-(4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)acetamide (CHMFL-KIT-64) as a Novel Orally Available Potent Inhibitor against Broad-Spectrum Mutants of 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019
作者:  Yun Wu;  Beilei Wang;  Junjie Wang;  Qi S(亓爽);  Fengming Zou;  Ziping Qi;  Feiyang Liu;  Wenchao Wang;  Qingsong Liu;  Jing Liu
浏览  |  Adobe PDF(5207Kb)  |  收藏  |  浏览/下载：129/65  |  提交时间：2020/10/20
Discovery of 4,7-Diamino-5-(4-phenoxyphenyl)-6-methylene-pyrinnido[5,4-b]pyrrolizines as Novel Bruton's Tyrosine Kinase Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 10, 页码: 4608-4627
作者:  Xue, Yu;  Song, Peiran;  Song, Zilan;  Wang, Aoli;  Tong, Linjiang;  Geng, Meiyu;  Ding, Jian;  Liu, Qingsong;  Sun, Liping;  Xie, Hua;  Zhang, Ao
浏览  |  Adobe PDF(6587Kb)  |  收藏  |  浏览/下载：151/107  |  提交时间：2019/08/23
Discovery of 2-((3-Acrylamido-4-methylphenyl)amino)-N-(2-methyl5-(3,4,5-trimethoxybenzamido)phenyI)-4-(methylamino)pyrimidine-5-carboxamide (CHMFL-BMX-078) as a Highly Potent and Selective Type II Irreversible Bone Marrow Kinase in the X Chromosome (BMX) Kinase Inhibitor 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 5, 页码: 1793-1816
作者:  Liang, Xiaofei;  Lv, Fengchao;  Wang, Beilei;  Yu, Kailin;  Wu, Hong;  Qi, Ziping;  Jiang, Zongru;  Chen, Cheng;  Wang, Aoli;  Miao, Weili;  Wang, Wenchao;  Hu, Zhenquan;  Liu, Juan;  Liu, Xiaochuan;  Zhao, Zheng;  Wang, Li;  Zhang, Shanchuan;  Ye, Zi;  Wang, Chu;  Ren, Tao;  Wang, Yinsheng;  Liu, Qingsong;  Liu, Jing
浏览  |  Adobe PDF(5919Kb)  |  收藏  |  浏览/下载：17302/7525  |  提交时间：2018/07/04
Origin of Magnetism in Hydrothermally Aged 2-Line Ferrihydrite Suspensions 期刊论文
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2017, 卷号: 51, 期号: 5, 页码: 2643-2651
作者:  Cao, Liang;  Jiang, Zhao-Xia;  Du, Yong-Hua;  Yin, Xin-Mao;  Xi, Shi-Bo;  Wen, Wen;  Roberts, Andrew P.;  Wee, Andrew T. S.;  Xiong, Yi-Min;  Liu, Qing-Song;  Gao, Xing-Yu
浏览  |  Adobe PDF(1264Kb)  |  收藏  |  浏览/下载：92/36  |  提交时间：2018/07/04
Moderate and strong static magnetic fields directly affect EGFR kinase domain orientation to inhibit cancer cell proliferation 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 27, 页码: 41527-41539
作者:  Zhang, Lei;  Wang, Jihao;  Wang, HongLei;  Wang, Wenchao;  Li, Zhiyuan;  Liu, Juanjuan;  Yang, Xingxing;  Ji, Xinmiao;  Luo, Yan;  Hu, Chen;  Hou, Yubin;  He, Qianqian;  Fang, Jun;  Wang, Junfeng;  Liu, Qingsong;  Li, Guohui;  Lu, Qingyou;  Zhang, Xin
浏览  |  Adobe PDF(11191Kb)  |  收藏  |  浏览/下载：103/43  |  提交时间：2017/11/21
Egfr  Magnetic Field  Stm  Cancer  
Moderate intensity static magnetic fields affect mitotic spindles and increase the antitumor efficacy of 5-FU and Taxol 期刊论文
BIOELECTROCHEMISTRY, 2016, 卷号: 109, 期号: 无, 页码: 31-40
作者:  Luo, Yan;  Ji, Xinmiao;  Liu, Juanjuan;  Li, Zhiyuan;  Wang, Wenchao;  Chen, Wei;  Wang, Junfeng;  Liu, Qingsong;  Zhang, Xin
浏览  |  Adobe PDF(2812Kb)  |  收藏  |  浏览/下载：96/49  |  提交时间：2017/11/10
Static Magnetic Field  Microtubule  Mitosis  Cancer Cells  5-fluorouracil  Cisplatin  
Discovery of N-(34(1-lsonicotinoylpiperidin-4-yl)oxy)-4methylpheny1)-3-(trifluoromethyl)benzamide (CHMFL-KIT-110) as a Selective, Potent, and Orally Available Type II c-KIT Kinase Inhibitor for Gastrointestinal Stromal Tumors (GISTs) 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 8, 页码: 3964-3979
作者:  Wang, Qang;  Liu, Feiyang;  Wang, Beilei;  Zou, Fengming;  Chen, Cheng;  Liu, Xiaochuan;  Wang, Aoli;  Qi, Shuang;  Wang, Wenchao;  Qi, Ziping;  Zhao, Zheng;  Hu, Zhenquan;  Wang, Wei;  Wang, Li;  Zhang, Shanchun;  Wang, Yuexiang;  Liu, Jing;  Liu, Qingsong
浏览  |  Adobe PDF(10221Kb)  |  收藏  |  浏览/下载：128/75  |  提交时间：2017/11/10
Ammonia Induces Autophagy through Dopamine Receptor D3 and MTOR 期刊论文
PLOS ONE, 2016, 卷号: 11, 期号: 4, 页码: 1-24
作者:  Li, Zhiyuan;  Ji, Xinmiao;  Wang, Wenchao;  Liu, Juanjuan;  Liang, Xiaofei;  Wu, Hong;  Liu, Jing;  Eggert, Ulrike S.;  Liu, Qingsong;  Zhang, Xin
浏览  |  Adobe PDF(7380Kb)  |  收藏  |  浏览/下载：95/44  |  提交时间：2017/11/10
Discovery of 2-((3-Amino-4-methylphenyl)amino)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide (CHMFL-ABL-053) as a Potent, Selective, and Orally Available BCR-ABL/SRC/p38 Kinase Inhibitor for Chronic Myeloid Leukemia 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 5, 页码: 1984-2004
作者:  Liang, Xiaofei;  Liu, Xiaochuan;  Wang, Beilei;  Zou, Fengming;  Wang, Aoli;  Qi, Shuan;  Chen, Cheng;  Zhao, Zheng;  Wang, Wenchao;  Qi, Ziping;  Lv, Fengchao;  Hu, Zhenquan;  Wang, Li;  Zhang, Shanchun;  Liu, Qingsong;  Liu, Jing
浏览  |  Adobe PDF(3635Kb)  |  收藏  |  浏览/下载：13708/5311  |  提交时间：2017/11/06
Moderate intensity static magnetic fields affect mitotic spindles and increase the antitumor efficacy of 5-FU and Taxol 期刊论文
Bioelectrochemistry, 2016, 卷号: 109, 期号: 无, 页码: 31-40
作者:  Yan Luo;  Xinmiao Ji;  Juanjuan Liu;  Zhiyuan Li;  Wenchao Wang;  Wei Chen;  Junfeng Wang;  Qingsong Liu;  Xin Zhang
Adobe PDF(4974Kb)  |  收藏  |  浏览/下载：235/181  |  提交时间：2016/01/11