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HFCAS OpenIR
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Inhibition of the deubiquitinating enzyme USP47 as a novel targeted therapy for hematologic malignancies expressing mutant EZH2 期刊论文
LEUKEMIA, 2022
作者:  Yang, Jing;  Weisberg, Ellen L.;  Qi, Shuang;  Ni, Wei;  Mei, Husheng;  Wang, Zuowei;  Meng, Chengcheng;  Zhang, Shengzhe;  Hou, Mingqi;  Qi, Ziping;  Wang, Aoli;  Jiang, Yunyun;  Jiang, Zongru;  Huang, Tao;  Liu, Qingwang;  Magin, Robert S.;  Doherty, Laura;  Wang, Wenchao;  Liu, Jing;  Buhrlage, Sara J.;  Liu, Qingsong;  Griffin, James D.
收藏  |  浏览/下载：83/0  |  提交时间：2022/02/14
Discovery of 4-((N-(2-(dimethylamino)ethyl)acrylamido)methyl)-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide (CHMFL-PDGFR-159) as a highly selective type II PDGFRα kinase inhibi 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018
作者:  Qiang Wang;  Feiyang Liu;  Qi S(亓爽);  Ziping Qi;  Beilei Wang;  Aoli Wang;  Zongru Jiang;  Wenchao Wang;  Qingsong Liu;  Jing Liu
浏览  |  Adobe PDF(5108Kb)  |  收藏  |  浏览/下载：133/55  |  提交时间：2020/10/20
Discovery of N-((1-(4-(3-(3-((6,7-Dimethoxyquinolin-3-yl)oxy)phenyl)ureido)-2-(trifluoromethyl)phenyl)piperidin-4-yl)methyl)propionamide (CHMFL-KIT-8140) as a Highly Potent Type II Inhibitor Capable of Inhibiting the T670I "Gatekeeper" Mutant of cKIT Kinase 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 18, 页码: 8456-8472
作者:  Li, Binhua;  Wang, Aoli;  Liu, Juan;  Qi, Ziping;  Liu, Xiaochuan;  Yu, Kailin;  Wu, Hong;  Chen, Cheng;  Hu, Chen;  Wang, Wenchao;  Wu, Jiaxin;  Hu, Zhenquan;  Ye, Ling;  Zou, Fengming;  Liu, Feiyang;  Wang, Beilei;  Wang, Li;  Ren, Tao;  Zhang, Shaojuan;  Bai, Mingfeng;  Zhang, Shanchun;  Liu, Jing;  Liu, Qingsong
浏览  |  Adobe PDF(2856Kb)  |  收藏  |  浏览/下载：1410/1299  |  提交时间：2017/11/21