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HFCAS OpenIR
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Different conformational responses of the beta(2)-adrenergic receptor-Gs complex upon binding of the partial agonist salbutamol or the full agonist isoprenaline 期刊论文
NATIONAL SCIENCE REVIEW, 2021, 卷号: 8
作者:  Yang, Fan;  Ling, Shenglong;  Zhou, Yingxin;  Zhang, Yanan;  Lv, Pei;  Liu, Sanling;  Fang, Wei;  Sun, Wenjing;  Hu, Liaoyuan A.;  Zhang, Longhua;  Shi, Pan;  Tian, Changlin
收藏  |  浏览/下载：57/0  |  提交时间：2021/11/01
cryo-EM structure  G protein-coupled receptor (GPCR)  partial and full agonists  conformational change  desensitization  
Structural mechanism of cooperative activation of the human calcium-sensing receptor by Ca2+ ions and L-tryptophan 期刊论文
CELL RESEARCH, 2021
作者:  Ling, Shenglong;  Shi, Pan;  Liu, Sanling;  Meng, Xianyu;  Zhou, Yingxin;  Sun, Wenjing;  Chang, Shenghai;  Zhang, Xing;  Zhang, Longhua;  Shi, Chaowei;  Sun, Demeng;  Liu, Lei;  Tian, Changlin
收藏  |  浏览/下载：50/0  |  提交时间：2021/04/26
A genetically encoded small-size fluorescent pair reveals allosteric conformational changes of G proteins upon its interaction with GPCRs by fluorescence lifetime based FRET 期刊论文
CHEMICAL COMMUNICATIONS, 2020, 卷号: 56
作者:  Shi, Pan;  Zhang, Yanan;  Lv, Pei;  Fang, Wei;  Ling, Shenglong;  Guo, Xiaoqi;  Li, Dong;  Liu, Sanling;  Sun, Demeng;  Zhang, Longhua;  Liu, Dongsheng;  Zheng, Ji-Shen;  Tian, Changlin
收藏  |  浏览/下载：24/0  |  提交时间：2020/10/26