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HFCAS OpenIR

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Effect of donor characteristics on T cell-replete haploidentical stem cell transplantation over the last 10 years at a single institution 期刊论文
BRITISH JOURNAL OF HAEMATOLOGY, 2021
作者:  Wu, Yibo;  Lai, Xiaoyu;  Shi, Jimin;  Tan, Yamin;  Zhao, Yanmin;  Yu, Jian;  Liu, Lizhen;  Zhang, Wei;  Huang, He;  Luo, Yi
收藏  |  浏览/下载：60/0  |  提交时间：2022/01/10
haploidentical  haematopoietic stem cell transplantation  donor selection  donor characteristics  donor age  female to male  
Targeting chaperon protein HSP70 as a novel therapeutic strategy for FLT3-ITD-positive acute myeloid leukemia 期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6
作者:  Hu, Chen;  Zou, Fengming;  Wang, Aoli;  Miao, Weili;  Liang, Qianmao;  Weisberg, Ellen L.;  Wang, Yinsheng;  Liu, Jing;  Wang, Wenchao;  Liu, Qingsong
收藏  |  浏览/下载：61/0  |  提交时间：2021/11/01
Selectively targeting FLT3-ITD mutants over FLT3-wt by a novel inhibitor for acute myeloid leukemia 期刊论文
HAEMATOLOGICA, 2021, 卷号: 106
作者:  Wang, Aoli;  Hu, Chen;  Chen, Cheng;  Liang, Xiaofei;  Wang, Beilei;  Zou, Fengming;  Yu, Kailin;  Li, Feng;  Liu, Qingwang;  Qi, Ziping;  Wang, Junjie;  Wang, Wenliang;  Wang, Li;  Weisberg, Ellen L.;  Wang, Wenchao;  Li, Lili;  Ge, Jian;  Xia, Ruixiang;  Liu, Jing;  Liu, Qingsong
收藏  |  浏览/下载：55/0  |  提交时间：2021/04/26
A narrative review of risk factors and interventions for cancer-related cognitive impairment 期刊论文
ANNALS OF TRANSLATIONAL MEDICINE, 2021, 卷号: 9
作者:  Bai, Lu;  Yu, Enyan
收藏  |  浏览/下载：49/0  |  提交时间：2021/04/26
Cancer  cognitive impairment  risk factors  treatment  
Isocitrate Dehydrogenase 2 Inhibitors for the Treatment of Hematologic Malignancies: Advances and Future Opportunities 期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2021, 卷号: 21
作者:  Huang, Feng;  Tian, Tian;  Wu, Yizhe;  Che, Jinxin;  Yang, Haiyan;  Dong, Xiaowu
收藏  |  浏览/下载：57/0  |  提交时间：2021/06/15
Isocitrate dehydrogenase 2  IDH2  mutant  inhibitors  structure-activity relationship  blood cance  
Repurposing of Kinase Inhibitors for Treatment of COVID-19 期刊论文
PHARMACEUTICAL RESEARCH, 2020, 卷号: 37
作者:  Weisberg, Ellen;  Parent, Alexander;  Yang, Priscilla L.;  Sattler, Martin;  Liu, Qingsong;  Liu, Qingwang;  Wang, Jinhua;  Meng, Chengcheng;  Buhrlage, Sara J.;  Gray, Nathanael;  Griffin, James D.
收藏  |  浏览/下载：40/0  |  提交时间：2020/10/26
Coronavirus  SARS-CoV-2  SARS-CoV  MERS-CoV  kinase inhibitors  pharmacokinetics  antiviral therapy  COVID-19  
Network-based analysis with primary cells reveals drug response landscape of acute myeloid leukemia 期刊论文
EXPERIMENTAL CELL RESEARCH, 2020, 卷号: 393
作者:  Chen, Cheng;  Wang, Li;  Li, Lili;  Wang, Aoli;  Huang, Tao;  Hu, Jie;  Zhao, Ming;  Liu, Feiyang;  Qi, Shuang;  Hu, Chen;  Wang, Wenliang;  Liu, Jing;  Ge, Jian;  Xia, Ruixiang;  Wang, Wenchao;  Liu, Qingsong
收藏  |  浏览/下载：42/0  |  提交时间：2020/11/26
Acute myeloid leukemia (AML)  Drug response  Gene mutations  
Discovery of N-(4-(6-Acetamidopyrimidin-4-yloxy)phenyl)-2-(2-(trifluoromethyl)phenyl)acetamide (CHMFL-FLT3-335) as a Potent FMS-like Tyrosine Kinase 3 Internal Tandem Duplication (FLT3-ITD) Mutant Selective Inhibitor for Acute Myeloid Leukemia 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 2, 页码: 875-892
作者:  Liang, Xiaofei;  Wang, Beilei;  Chen, Cheng;  Wang, Aoli;  Hu, Chen;  Zou, Fengming;  Yu, Kailin;  Liu, Qingwang;  Li, Feng;  Hu, Zhenquan;  Lu, Tingting;  Wang, Junjie;  Wang, Li;  Weisberg, Ellen L.;  Li, Lili;  Xia, Ruixiang;  Wang, Wenchao;  Ren, Tao;  Ge, Jian;  Liu, Jing;  Liu, Qinsong
浏览  |  Adobe PDF(13868Kb)  |  收藏  |  浏览/下载：377/322  |  提交时间：2020/05/21
Discovery of (S)-2-amino-N-(5-(6-chloro-5-(3-methylphenylsulfonamido)pyridin-3-yl)-4-methylthiazol-2-yl)-3-methylbutanamide (CHMFL-PI3KD-317) as a potent and selective phosphoinositide 3-kinase delta (PI3K delta) inhibitor 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 156, 页码: 831-846
作者:  Liang, Xiaofei;  Li, Feng;  Chen, Cheng;  Jiang, Zongru;  Wang, Aoli;  Liu, Xiaochuan;  Ge, Juan;  Hu, Zhenquan;  Yu, Kailin;  Wang, Wenliang;  Zou, Fengming;  Liu, Qingwang;  Wang, Beilei;  Wang, Li;  Zhang, Shanchun;  Wang, Yuxin;  Liu, Qingsong;  Liu, Jing
收藏  |  浏览/下载：58/0  |  提交时间：2019/12/10
PI3K delta  Kinase inhibitor  Acute myeloid leukemia  Structure-activity relationship  
Tumor suppressor miR-128-3p inhibits metastasis and epithelial-mesenchymal transition by targeting ZEB1 in esophageal squamous-cell cancer 期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2018, 卷号: 50
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收藏  |  浏览/下载：32/0  |  提交时间：2020/10/26
ACUTE LYMPHOBLASTIC-LEUKEMIA  GENOME-WIDE ASSOCIATION  EMT-ACTIVATOR ZEB1  CIRCULATING MICRORNAS  TRANSCRIPTION FACTORS  PROMOTES INVASION  MIRNA EXPRESSION  FEEDBACK LOOP  CARCINOMA  SURVIVAL  miR-128-3p  esophageal squamous-cell carcinoma  ZEB1  epithelial-mesenchymal transition  invasion and metastasis