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High-dose Aumolertinib as First-line Treatment in Patients With Brain Metastases Associated With EGFR Mutated NSCLC 期刊论文
JOURNAL OF THORACIC ONCOLOGY, 2022, 卷号: 17
作者:  Fan, Y.
收藏  |  浏览/下载：40/0  |  提交时间：2022/12/23
NSCLC  EGFR TKI  Brain Metastases  
The radiomic-clinical model using the SHAP method for assessing the treatment response of whole-brain radiotherapy: a multicentric study 期刊论文
EUROPEAN RADIOLOGY, 2022
作者:  Wang, Yixin;  Lang, Jinwei;  Zuo, Joey Zhaoyu;  Dong, Yaqin;  Hu, Zongtao;  Xu, Xiuli;  Zhang, Yongkang;  Wang, Qinjie;  Yang, Lizhuang;  Wong, Stephen T. C.;  Wang, Hongzhi;  Li, Hai
收藏  |  浏览/下载：35/0  |  提交时间：2022/12/23
Magnetic resonance imaging  Neoplasm metastasis  Machine learning  Radiotherapy  Game theory  
Novel HIVEP1-ALK fusion in a patient with lung adenocarcinoma demonstrating sensitivity to alectinib: a case report 期刊论文
TRANSLATIONAL LUNG CANCER RESEARCH, 2022, 卷号: 11
作者:  Gu, Xiaodong;  Wang, Wenxian;  Wu, Wei;  Zhang, Yiping;  Shao, Lan;  Santarpia, Mariacarmela;  Christopoulos, Petros;  Myall, Nathaniel J.;  Shi, Zhiyong;  Lou, Guangyuan
收藏  |  浏览/下载：40/0  |  提交时间：2022/12/22
Non-small cell lung cancer (NSCLC)  HIVEP1-ALK  alectinib  intergenic region (IGR)  case report  
Integrated genomic and DNA methylation analysis of patients with advanced non-small cell lung cancer with brain metastases 期刊论文
MOLECULAR BRAIN, 2021, 卷号: 14
作者:  Xu, Yanjun;  Huang, Zhiyu;  Yu, Xiaoqing;  Chen, Kaiyan;  Fan, Yun
收藏  |  浏览/下载：72/0  |  提交时间：2022/01/25
Brain metastases  Predictive biomarker  DNA methylation  Somatic mutation  Advanced non-small cell lung cancer (advanced NSCLC)  
A nomogram model based on peripheral blood lymphocyte subsets to assess the prognosis of non-small cell lung cancer patients treated with immune checkpoint inhibitors 期刊论文
TRANSLATIONAL LUNG CANCER RESEARCH, 2021
作者:  Xu, Xiaoling;  Wang, Ding;  Chen, Wei;  Li, Na;  Suwinski, Rafal;  Rossi, Antonio;  Rosell, Rafael;  Zhong, Jianxiang;  Fan, Yun
收藏  |  浏览/下载：76/0  |  提交时间：2022/02/14
Immune checkpoint inhibitor (ICI)  non-small cell lung cancer (NSCLC)  peripheral blood lymphocyte subsets  
Pyrotinib plus capecitabine for HER2-positive metastatic breast cancer patients with brain metastases (PERMEATE): A multicenter, single-arm phase II study. 期刊论文
JOURNAL OF CLINICAL ONCOLOGY, 2021, 卷号: 39
作者:  Yan, Min;  Ouyang, Quchang;  Sun, Tao;  Niu, Limin;  Yang, Jin;  Li, Li;  Song, Yuhua;  Hao, Chunfang;  Chen, Zhanhong
收藏  |  浏览/下载：41/0  |  提交时间：2022/01/10
Treatment and Prognosis of Solid and Cystic Brain Metastases in Patients with Non-Small-Cell Lung Cancer 期刊论文
CANCER MANAGEMENT AND RESEARCH, 2021, 卷号: 13
作者:  Xu, Yi-Bing;  Zhang, Yiping;  Song, Zhengbo;  Wang, Wenxian;  Shao, Lan
收藏  |  浏览/下载：54/0  |  提交时间：2021/09/06
cystic brain metastases  tyrosine kinase inhibitors  chemotherapy  radiation therapy  lung cancer  
Osimertinib successfully combats EGFR-negative glioblastoma cells by inhibiting the MAPK pathway 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020
作者:  Chen, Cheng;  Cheng, Chuan-dong;  Wu, Hong;  Wang, Zuo-wei;  Wang, Li;  Jiang, Zong-ru;  Wang, Ao-li;  Hu, Chen;  Dong, Yong-fei;  Niu, Wan-xiang;  Qi, Shuang;  Qi, Zi-ping;  Liu, Jing;  Wang, Wen-chao;  Niu, Chao-shi;  Liu, Qing-song
浏览  |  Adobe PDF(3476Kb)  |  收藏  |  浏览/下载：101/36  |  提交时间：2020/11/26
glioblastoma  osimertinib  temozolamide  MAPK-signaling pathway  MNK  eukaryotic translation initiation factor 4E  
阿帕替尼联合放化疗治疗非小细胞肺癌脑转移患者的近期疗效与安全性 期刊论文
中国肿瘤生物治疗杂志, 2020, 卷号: 27
作者:  尹雪;  胡宗涛;  徐秀理;  张文康;  崔相利;  高世乐
收藏  |  浏览/下载：35/0  |  提交时间：2020/10/26
non-small cell lung cancer (NSCLC)  brain metastasis  apatinib  concurrent radiochemotherapy  short-term efficacy  safety  非小细胞肺癌  脑转移  阿帕替尼  同步放化疗  近期疗效  安全性  
Efficacy of afatinib, an irreversible ErbB family blocker, in the treatment of intracerebral metastases of non-small cell lung cancer in mice 期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38
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收藏  |  浏览/下载：30/0  |  提交时间：2020/10/26
BRAIN METASTASES  CEREBROSPINAL-FLUID  GEFITINIB  INHIBITORS  CARCINOMA  RADIATION  ERLOTINIB  afatinib  tyrosine kinase inhibitor  non-small cell lung cancer  brain metastasis  pharmacokinetic/pharmacodynamics  pEGFR