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Alantolactone induces concurrent apoptosis and GSDME-dependent pyroptosis of anaplastic thyroid cancer through ROS mitochondria-dependent caspase pathway 期刊论文
PHYTOMEDICINE, 2023, 卷号: 108
作者:  Hu, Yiqun;  Wen, Qingliang;  Cai, Yefeng;  Liu, Yunye;  Ma, Wenli;  Li, Qinglin;  Song, Fahuan;  Guo, Yawen;  Zhu, Lei;  Ge, Jingyan;  Zeng, Qian;  Wang, Jiahui;  Yin, Changtian;  Zheng, Guowan;  Ge, Minghua
收藏  |  浏览/下载：51/0  |  提交时间：2022/12/23
Alantolactone  Anaplastic thyroid cancer  ROS  Pyroptosis  Apoptosis  
Darinaparsin (ZIO-101) enhances the sensitivity of small-cell lung cancer to PARP inhibitors 期刊论文
ACTA PHARMACOLOGICA SINICA, 2022
作者:  Cao, Guo-Zhen;  Ma, Li-Ying;  Zhang, Zong-Hui;  Wang, Xiao-Lin;  Hua, Jing-Han;  Zhang, Jia-Hui;  Lv, Yang;  Zhang, Shao-Bo;  Ou, Jian;  Lin, Wen-Chu
收藏  |  浏览/下载：48/0  |  提交时间：2022/12/22
small-cell lung cancer  H3  3  PARP1  PARP inhibitor  darinaparsin  combination treatment  
S3I-201 derivative incorporating naphthoquinone unit as effective STAT3 inhibitors: Design, synthesis and anti-gastric cancer evaluation 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2022, 卷号: 71
作者:  Li, Haobin;  Cai, Maohua;  Cao, Fei;  Yu, Dehua;  Yang, Jing;  Yu, Wenkai;  Chu, Chu;  Guan, Xiaoqing;  Qin, Jiang-Jiang;  Dong, Jinyun
收藏  |  浏览/下载：43/0  |  提交时间：2022/12/22
STAT3 inhibitor  Quinone derivative  S3I-201  Anti -gastric cancer drug  
Cold Atmospheric Plasma Inhibits the Proliferation of CAL-62 Cells through the ROS-Mediated PI3K/Akt/mTOR Signaling Pathway 期刊论文
SCIENCE AND TECHNOLOGY OF NUCLEAR INSTALLATIONS, 2022, 卷号: 2022
作者:  Liu, Fang;  Zhou, Yuanyuan;  Song, Wencheng;  Wang, Hongzhi
收藏  |  浏览/下载：38/0  |  提交时间：2022/12/22
Inhibition of STAT3 Signaling Pathway by Terphenyllin Suppresses Growth and Metastasis of Gastric Cancer 期刊论文
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13
作者:  Yu, Dehua;  Qi, Simin;  Guan, Xiaoqing;  Yu, Wenkai;  Yu, Xuefei;  Cai, Maohua;  Li, Qinglin;  Wang, Weiyi;  Zhang, Weidong;  Qin, Jiang-Jiang
收藏  |  浏览/下载：33/0  |  提交时间：2022/12/23
STAT3  inhibitor  natural product  gastric cancer  terphenyllin  
Nano-selenium attenuates mitochondrial-associated apoptosis via the PI3K/AKT pathway in nickel-induced hepatotoxicity in vivo and in vitro 期刊论文
ENVIRONMENTAL TOXICOLOGY, 2021
作者:  Wang, Caixia;  Gu, Zhangyu;  Gu, Xueyan;  Tan, Xinyue;  Wang, Shuang;  Zhang, Rui;  Li, Ruifen;  Sun, Mingkun;  Gui, Chunyan;  Li, Sheng;  Ye, Yixing;  Ma, Jianhua;  Su, Li;  Liang, Changhao
收藏  |  浏览/下载：46/0  |  提交时间：2021/11/01
hepatotoxicity  mitochondrial apoptosis  Nano-Se  nickel  PI3K-Akt pathway  
Study on the Antitumor Effect and Glycolysis of Andrographolide in Anaplastic Thyroid Carcinoma 期刊论文
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2021, 卷号: 2021
作者:  Yang, Ke;  Wu, Ke;  Feng, Jianguo;  Yutian, Ling;  Zhu, Xin;  Xu, Dong
收藏  |  浏览/下载：56/0  |  提交时间：2021/09/06
An upward 9.4 T static magnetic field inhibits DNA synthesis and increases ROS-P53 to suppress lung cancer growth 期刊论文
TRANSLATIONAL ONCOLOGY, 2021
作者:  Yang, Xingxing;  Song, Chao;  Zhang, Lei;  Wang, Junjun;  Yu, Xin;  Yu, Biao;  Zablotskii, Vitalii;  Zhang, Xin
浏览  |  Adobe PDF(4320Kb)  |  收藏  |  浏览/下载：78/30  |  提交时间：2021/12/15
Silver nanoparticle-activated COX2/PGE2 axis involves alteration of lung cellular senescence in vitro and in vivo 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2020, 卷号: 204
作者:  Chen, Biao;  Chai, Qing;  Xu, Shengmin;  Li, Qian;  Wu, Tao;  Chen, Shaopeng;  Wu, Lijun
收藏  |  浏览/下载：59/0  |  提交时间：2020/11/30
Silver nanoparticles  Lung cellular senescence  COX2  SASP  Human respiratory system  
Integration of Transcriptomics and Metabolomics Reveals the Antitumor Mechanism Underlying Shikonin in Colon Cancer 期刊论文
FRONTIERS IN PHARMACOLOGY, 2020, 卷号: 11
作者:  Chen, Yang;  Gao, Yun;  Yi, Xiaojiao;  Zhang, Jinghui;  Chen, Zhongjian;  Wu, Yongjiang
收藏  |  浏览/下载：54/0  |  提交时间：2020/12/28
transcriptomics  metabolomics  shikonin  colon cancer  purine metabolism