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Acetaldehyde induces similar cytotoxic and genotoxic risks in BEAS-2B cells and HHSteCs: involvement of differential regulation of MAPK/ERK and PI3K/AKT pathways 期刊论文
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 2023, 卷号: 30
作者:  Zhang, Jingni;  Wang, Hongjuan;  Chen, Huan;  Liu, Yong;  Wang, An;  Hou, Hongwei;  Hu, Qingyuan
收藏  |  浏览/下载：31/0  |  提交时间：2023/11/17
Acetaldehyde  Cytotoxicity  Genotoxicity  BEAS-2B cells  HHSteCs  MAPK/ERK  PI3K/AKT  
Bronchial epithelial SIRT1 deficiency exacerbates cigarette smoke induced emphysema in mice through the FOXO3/PINK1 pathway 期刊论文
EXPERIMENTAL LUNG RESEARCH, 2022
作者:  Jiang, Hui;  Jiang, Yaona;  Xu, Yuanri;  Yuan, Dong;  Li, Yaqing
收藏  |  浏览/下载：52/0  |  提交时间：2022/03/21
COPD  FOXO3  mitophagy  PINK1  SIRT1  
Decreased mitochondrial DNA copy number in nerve cells and the hippocampus during nicotine exposure is mediated by autophagy 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2021, 卷号: 226
作者:  Wang, Hongjuan;  Chen, Huan;  Han, Shulei;  Fu, Yaning;  Tian, Yushan;  Liu, Yong;  Wang, An;  Hou, Hongwei;  Hu, Qingyuan
收藏  |  浏览/下载：55/0  |  提交时间：2021/11/15
nicotine  mtDNA copy number  autophagy  mitochondrial abnormalities  
Senescence associated long non-coding RNA 1 regulates cigarette smoke-induced senescence of type II alveolar epithelial cells through sirtuin-1 signaling 期刊论文
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH, 2021, 卷号: 49
作者:  Yuan, Dong;  Liu, Yuanshun;  Li, Mengyu;  Zhou, Hongbin;  Cao, Liming;  Zhang, Xiaoqin;  Li, Yaqing
收藏  |  浏览/下载：45/0  |  提交时间：2021/03/15
Chronic obstructive pulmonary disease  alveolar epithelial cells  sirtuin-1  cellular senescence  long non-coding RNA  cigarette smoke  
Combined cell death of co-exposure to aldehyde mixtures on human bronchial epithelial BEAS-2B cells: Molecular insights into the joint action 期刊论文
CHEMOSPHERE, 2020, 卷号: 244
作者:  Zhang, Sen;  Zhang, Jingni;  Cheng, Wanyan;  Chen, Huan;  Wang, An;  Liu, Yong;  Hou, Hongwei;  Hu, Qingyuan
收藏  |  浏览/下载：54/0  |  提交时间：2020/11/26
Formaldehyde  Acrolein  Combined action  Cell death  Apoptotic signaling pathway  
Transforming brain signals related to value evaluation and self-control into behavioral choices 期刊论文
HUMAN BRAIN MAPPING, 2019, 卷号: 40, 期号: 4, 页码: 1049-1061
作者:  Zha, Rujing;  Bu, Junjie;  Wei, Zhengde;  Han, Long;  Zhang, Pengyu;  Ren, Jiecheng;  Li, Ji-An;  Wang, Ying;  Yang, Lizhuang;  Vollstaedt-Klein, Sabine;  Zhang, Xiaochu
浏览  |  Adobe PDF(1076Kb)  |  收藏  |  浏览/下载：1580/45  |  提交时间：2020/05/21
functional magnetic resonance imaging  intertemporal decision-making  multivoxel pattern analysis  self-control  valuation  
Genotoxicity evaluation of carbon monoxide and 1,3-butadiene using a new joint technology: the in vitro gamma H2AX HCS assay combined with air-liquid interface system 期刊论文
TOXICOLOGY MECHANISMS AND METHODS, 2019, 卷号: 29, 期号: 1, 页码: 1-7
作者:  Zhang, Sen;  Chen, Huan;  Wang, An;  Liu, Yong;  Hou, Hongwei;  Hu, Qingyuan
收藏  |  浏览/下载：62/0  |  提交时间：2020/07/14
gamma H2AX  genotoxicity  high content screening  carbon monoxide  1,3-butadiene  air-liquid interface system  
Tobacco, air pollution, environmental carcinogenesis, and thoughts on conquering strategies of lung cancer 期刊论文
CANCER BIOLOGY & MEDICINE, 2019, 卷号: 16
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收藏  |  浏览/下载：48/0  |  提交时间：2020/10/26
NF-KAPPA-B  SOMATIC MUTATIONS  GENOMIC VARIATIONS  CIGARETTE-SMOKE  GENE-EXPRESSION  NEVER  INFLAMMATION  PROFILES  RISK  ADENOCARCINOMA  Lung cancer  tobacco smoke  air pollution  smohaze  carcinogenesis  
Combined effects of co-exposure to formaldehyde and acrolein mixtures on cytotoxicity and genotoxicity in vitro 期刊论文
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 2018, 卷号: 25, 期号: 25, 页码: 25306-25314
作者:  Zhang, Sen;  Chen, Huan;  Wang, An;  Liu, Yong;  Hou, Hongwei;  Hu, Qingyuan
收藏  |  浏览/下载：27/0  |  提交时间：2019/11/11
Formaldehyde  Acrolein  Genotoxicity  Cytotoxicity  Combined effects  
基于TDLAS技术测量卷烟燃吸逐口耗氧量 期刊论文
烟草科技, 2018, 卷号: 051
作者:  邓楠;  邢昆明;  张明建;  王乐;  张柯;  计敏;  李志刚;  王安;  刘勇;  李斌
收藏  |  浏览/下载：38/0  |  提交时间：2020/11/25
可调谐激光二极管吸收光谱  卷烟  耗氧量  逐口抽吸