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HFCAS OpenIR

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Predicting and overcoming resistance to CDK9 inhibitors for cancer therapy 期刊论文
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13
作者:  Hua, Chen;  Shena, Lijuan;  Zoua, Fengming;  Wua, Yun;  Wanga, Beilei;  Wanga, Aoli;  Wud, Chao;  Wanga, Li;  Liua, Jing;  Wanga, Wenchao;  Liua, Qingsong
收藏  |  浏览/下载：39/0  |  提交时间：2023/11/10
Acquired resistance mutations  CDK9 inhibitors  Transcription  Single nucleotide polymorphisms  BAY1251152  
Proteomics Analysis Revealed Smad3 as a Potential Target of the Synergistic Anti-tumor Activity of Disulfiram and Cisplatin in Ovarian Cancer 期刊论文
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2023, 卷号: 23
作者:  Du, Ruiping;  Sun, Feilong;  Li, Kai;  Qi, Jian;  Zhong, Wen;  Wang, Wei;  Sun, Qiuyan;  Deng, Qingmei;  Wang, Hongzhi;  Nie, Jinfu;  Ding, Chen;  Hong, Bo
收藏  |  浏览/下载：29/0  |  提交时间：2023/11/10
Disulfiram  cisplatin resistance  ovarian cancer  proteomics analysis  SMAD3  lactate dehydrogenase  
The reversal of anti-HER2 resistance in advanced HER2-positive breast cancer using apatinib: two cases reports and literature review 期刊论文
TRANSLATIONAL CANCER RESEARCH, 2022
作者:  He, Libin;  Shen, Xiabo;  Liu, Yiyuan;  Gao, Lu;  Wu, Jiayi;  Yu, Chang;  Li, Guangliang;  Wang, Xiaojia;  Shao, Xiying
收藏  |  浏览/下载：41/0  |  提交时间：2022/12/23
Advanced human epidermal growth factor receptor 2-positive breast cancer (advanced HER2-positive breast cancer)  apatinib  case report  
Duplex real-time fluorescent recombinase polymerase amplification for the rapid and sensitive detection of two resistance genes in drug-resistant Staphylococcus aureus 期刊论文
JOURNAL OF MICROBIOLOGICAL METHODS, 2022, 卷号: 202
作者:  Shi, Zhonglin;  Li, Yanan;  Hu, Anzhong;  Cui, Junsheng;  Shao, Min;  Zhu, Ling;  Yang, Ke;  Liu, Yong;  Deng, Guoqing;  Zhu, Cancan
收藏  |  浏览/下载：37/0  |  提交时间：2022/12/23
Drug -resistant Staphylococcus aureus  ermA  mecA  Recombinase polymerase amplification  Resistance genes  
A designed antimicrobial peptide with potential ability against methicillin resistant Staphylococcus aureus 期刊论文
FRONTIERS IN MICROBIOLOGY, 2022, 卷号: 13
作者:  Yuan, Bingqian;  Lu, Xiaoyu;  Yang, Min;  He, Qiyi;  Cha, Zhuocen;  Fang, Yaqun;  Yang, Yan;  Xu, Lei;  Yan, Jingting;  Lai, Ren;  Wang, Aili;  Yu, Xiaodong;  Duan, Zilei
收藏  |  浏览/下载：49/0  |  提交时间：2022/12/23
Staphylococcus aureus  cathelicidin  antimicrobial peptides  GW18  drug-resistant  
Drug-resistant HER2-positive breast cancer: Molecular mechanisms and overcoming strategies 期刊论文
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13
作者:  Wu, Xiaofan;  Yang, Hongjian;  Yu, Xingfei;  Qin, Jiang-Jiang
收藏  |  浏览/下载：50/0  |  提交时间：2022/12/22
HER2  breast cancer  targeted therapy  drug resistance  overcoming strategies  
Expert consensus on the diagnosis and treatment of NTRK gene fusion solid tumors in China 期刊论文
THORACIC CANCER, 2022
作者:  Xu, Chunwei;  Si, Lu;  Wang, Wenxian;  Li, Ziming;  Song, Zhengbo;  Wang, Qian;  Liu, Aijun;  Yu, Jinpu;  Fang, Wenfeng;  Zhong, Wenzhao;  Wang, Zhijie;  Zhang, Yongchang;  Liu, Jingjing;  Zhang, Shirong;  Cai, Xiuyu;  Liu, Anwen;  Li, Wen;  Zhan, Ping;  Liu, Hongbing;  Lv, Tangfeng;  Miao, Liyun;  Min, Lingfeng;  Chen, Yu;  Yuan, Jingping;  Wang, Feng;  Jiang, Zhansheng;  Lin, Gen;  Pu, Xingxiang;  Lin, Rongbo;  Liu, Weifeng;  Rao, Chuangzhou;  Lv, Dongqing;  Yu, Zongyang;  Lei, Lei;  Li, Xiaoyan;  Tang, Chuanhao;  Zhou, Chengzhi;  Zhang, Junping;  Xue, Junli;  Guo, Hui;  Chu, Qian;  Meng, Rui;  Wu, Jingxun;  Zhang, Rui;  Hu, Xiao;  Zhou, Jin;  Zhu, Zhengfei;  Li, Yongheng;  Qiu, Hong;  Xia, Fan;  Lu, Yuanyuan;  Chen, Xiaofeng;  Ge, Rui;  Dai, Enyong;  Han, Yu;  Pan, Weiwei;  Luo, Jiancheng;  Jia, Hongtao;  Dong, Xiaowei;  Pang, Fei;  Wang, Kai;  Wang, Liping;  Zhu, Youcai;  Xie, Yanru;  Lin, Xinqin;  Cai, Jing;  Wei, Jia;  Lan, Fen;  Feng, Huijing;  Wang, Lin;  Du, Yingying;  Yao, Wang;  Shi, Xuefei;  Niu, Xiaomin;  Yuan, Dongmei;  Yao, Yanwen;  Huang, Jianhui;  Zhang, Yinbin;  Sun, Pingli;  Wang, Hong;  Ye, Mingxiang;  Wang, Dong;  Wang, Zhaofeng;  Wan, Bing;  Lv, Donglai;  Wei, Qing;  Kang, Jin;  Zhang, Jiatao;  Zhang, Chao;  Yu, Genhua;  Ou, Juanjuan;  Shi, Lin;  Li, Zhongwu;  Liu, Zhefeng;  Liu, Jing;  Yang, Nong;  Wu, Lin;  Wang, Huijuan;  Jin, Gu;  Yang, Liu;  Wang, Guansong;  Fang, Meiyu;  Fang, Yong;  Li, Yuan;  Wang, Xiaojia;  Zhang, Yiping;  Ma, Shenglin;  Wang, Biyun;  Zhang, Xiaotian;  Song, Yong;  Lu, Yuanzhi
收藏  |  浏览/下载：53/0  |  提交时间：2022/12/22
fusion  precision medicine  solid tumor  targeted therapy  tyrosine receptor kinase  
Targeting KRAS mutant cancers: from druggable therapy to drug resistance 期刊论文
MOLECULAR CANCER, 2022, 卷号: 21
作者:  Zhu, Chunxiao;  Guan, Xiaoqing;  Zhang, Xinuo;  Luan, Xin;  Song, Zhengbo;  Cheng, Xiangdong;  Zhang, Weidong;  Qin, Jiang-Jiang
收藏  |  浏览/下载：35/0  |  提交时间：2022/12/23
KRAS mutations  Druggable  Resistance  Combination therapy  
Key Considerations in Targeted Protein Degradation Drug Discovery and Development 期刊论文
FRONTIERS IN CHEMISTRY, 2022, 卷号: 10
作者:  Qin, Liena;  Dai, Han;  Wang, Junfeng
收藏  |  浏览/下载：32/0  |  提交时间：2022/12/23
targeted protein degradation  PROTAC  molecular glue  chemically induced proximity  drug discovery and development  
The Role of Anti-EGFR Monoclonal Antibody in mCRC Maintenance Therapy 期刊论文
FRONTIERS IN MOLECULAR BIOSCIENCES, 2022, 卷号: 9
作者:  Yuan, Meiqin;  Wang, Zeng;  Lv, Wangxia;  Pan, Hongming
收藏  |  浏览/下载：54/0  |  提交时间：2022/05/16
mCRC  maintenance therapy  EGFR  monoclonal antibody  panitumumab  cetuximab