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HFCAS OpenIR

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Overexpression of FAM83A Is Associated with Poor Prognosis of Lung Adenocarcinoma 期刊论文
JOURNAL OF ONCOLOGY, 2022, 卷号: 2022
作者:  Liu, Xin;  Fu, Meng;  Xia, Daqing;  Ji, Zimei;  Hu, Nana;  Leng, Zaijun;  Xie, Wang;  Fang, Yuan;  Zhang, Junqiang
收藏  |  浏览/下载：35/0  |  提交时间：2022/12/22
Impact of clinical and molecular features on efficacy and outcome of patients with non-small cell lung cancer receiving second-line osimertinib 期刊论文
BMC CANCER, 2022, 卷号: 22
作者:  Jin, Ying;  Lin, Chen;  Shi, Xun;  He, Qiong;  Yan, Junrong;  Yu, Xinmin;  Chen, Ming
收藏  |  浏览/下载：38/0  |  提交时间：2022/12/23
Clinical and molecular features  Efficacy and outcome  EGFR T790M mutation  Non-small-cell lung cancer  Osimertinib  
HER2 exon 20 insertion mutations in lung adenocarcinoma with leptomeningeal metastasis: a case report and response to poziotinib 期刊论文
ANNALS OF PALLIATIVE MEDICINE, 2022, 卷号: 11
作者:  Fan, Ying;  Qin, Jing;  Han, Na;  Lu, Hongyang
收藏  |  浏览/下载：34/0  |  提交时间：2022/12/23
Leptomeningeal metastasis (LM)  cerebrospinal fluid  HER2 exon 20 insertion mutations  poziotinib  case report  
Progress on treatment of MET signaling pathway in non-small cell lung cancer 期刊论文
INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY, 2020
作者:  Yu, Xiaoqing;  Yu, Sizhe;  Fan, Yun
收藏  |  浏览/下载：44/0  |  提交时间：2020/11/26
MET  Dysregulation  Overexpression  Amplification  Non-small cell lung cancer  
Osimertinib successfully combats EGFR-negative glioblastoma cells by inhibiting the MAPK pathway 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020
作者:  Chen, Cheng;  Cheng, Chuan-dong;  Wu, Hong;  Wang, Zuo-wei;  Wang, Li;  Jiang, Zong-ru;  Wang, Ao-li;  Hu, Chen;  Dong, Yong-fei;  Niu, Wan-xiang;  Qi, Shuang;  Qi, Zi-ping;  Liu, Jing;  Wang, Wen-chao;  Niu, Chao-shi;  Liu, Qing-song
浏览  |  Adobe PDF(3476Kb)  |  收藏  |  浏览/下载：101/36  |  提交时间：2020/11/26
glioblastoma  osimertinib  temozolamide  MAPK-signaling pathway  MNK  eukaryotic translation initiation factor 4E  
Discovery of N-(5-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-4-methoxy-2-(4-methyl-1,4-diazepan-1-yl)phenyl)acrylamide (CHMFL-ALK/EGFR-050) as a potent ALK/EGFR dual kinase inhibitor capable of overcoming a variety of ALK/EGFR associated drug resistant mutants in NSCLC 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 139, 期号: 无, 页码: 674-697
作者:  Chen, Yongfei;  Wu, Jiaxin;  Wang, Aoli;  Qi, Ziping;  Jiang, Taoshan;  Chen, Cheng;  Zou, Fengming;  Hu, Chen;  Wang, Wei;  Wu, Hong;  Hu, Zhenquan;  Wang, Wenchao;  Wang, Beilei;  Wang, Li;  Ren, Tao;  Zhang, Shanchun;  Liu, Qingsong;  Liu, Jing
浏览  |  Adobe PDF(12656Kb)  |  收藏  |  浏览/下载：21281/11466  |  提交时间：2018/08/17
Egfr  Alk  Dual Kinase Inhibitor  Non-small Cell Lung Cancer  
双色比率荧光寡核苷酸探针的设 计及其在生物分析中的应用 学位论文
, 合肥: 中国科学技术大学, 2017
作者:  宁殿华
Adobe PDF(4434Kb)  |  收藏  |  浏览/下载：44/0  |  提交时间：2018/01/17
Clinical characteristics and response to tyrosine kinase inhibitors of patients with non-small cell lung cancer harboring uncommon epidermal growth factor receptor mutations 期刊论文
CHINESE JOURNAL OF CANCER RESEARCH, 2017, 卷号: 29
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收藏  |  浏览/下载：33/0  |  提交时间：2020/10/26
EGFR MUTATIONS  GEFITINIB TREATMENT  1ST-LINE TREATMENT  OPEN-LABEL  RARE  MULTICENTER  ERLOTINIB  GENE  CHEMOTHERAPY  EFFICACY  Non-small cell lung cancer  EGFR  uncommon mutation  target therapy  
Efficacy of afatinib, an irreversible ErbB family blocker, in the treatment of intracerebral metastases of non-small cell lung cancer in mice 期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38
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收藏  |  浏览/下载：30/0  |  提交时间：2020/10/26
BRAIN METASTASES  CEREBROSPINAL-FLUID  GEFITINIB  INHIBITORS  CARCINOMA  RADIATION  ERLOTINIB  afatinib  tyrosine kinase inhibitor  non-small cell lung cancer  brain metastasis  pharmacokinetic/pharmacodynamics  pEGFR  
Discovery and characterization of a novel irreversible EGFR mutants selective and potent kinase inhibitor CHMFL-EGFR-26 with a distinct binding mode 期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 11, 页码: 18359-18372
作者:  Hu, Chen;  Wang, Aoli;  Wu, Hong;  Qi, Ziping;  Li, Xixiang;  Yan, Xiao-E;  Chen, Cheng;  Yu, Kailin;  Zou, Fengming;  Wang, Wenchao;  Wang, Wei;  Wu, Jiaxin;  Liu, Juan;  Wang, Beilei;  Wang, Li;  Ren, Tao;  Zhang, Shanchun;  Yun, Cai-Hong;  Liu, Jing;  Liu, Qingsong
浏览  |  Adobe PDF(6153Kb)  |  收藏  |  浏览/下载：183/48  |  提交时间：2018/07/04
Egfr  Egfrt790m  Nsclc  Kinase Inhibitors  Drug Resistance