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HFCAS OpenIR

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Bronchial epithelial SIRT1 deficiency exacerbates cigarette smoke induced emphysema in mice through the FOXO3/PINK1 pathway 期刊论文
EXPERIMENTAL LUNG RESEARCH, 2022
作者:  Jiang, Hui;  Jiang, Yaona;  Xu, Yuanri;  Yuan, Dong;  Li, Yaqing
收藏  |  浏览/下载：52/0  |  提交时间：2022/03/21
COPD  FOXO3  mitophagy  PINK1  SIRT1  
Integrated Transcriptomics and Reverse Pharmacophore Mapping-based Network Pharmacology to Explore the Mechanisms of Natural Compounds against Doxorubicin-induced Cardiotoxicity 期刊论文
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2022, 卷号: 25
作者:  Zhu, Junfeng;  Yi, Xiaojiao;  Ding, Haiying;  Zhong, Like;  Fang, Luo
收藏  |  浏览/下载：44/0  |  提交时间：2022/12/22
Doxorubicin-induced cardiotoxicity  natural compounds  mechanism of action  gene expression profile  bioinformatics  network pharmacology  
1 beta-Hydroxyalantolactone from Inulae Flos alleviated the progression of pulmonary fibrosis via inhibiting JNK/FOXO1/NF-kappa B pathway 期刊论文
INTERNATIONAL IMMUNOPHARMACOLOGY, 2021, 卷号: 101
作者:  Yu, Bing;  Jin, Xiao-Qing;  Yu, Wen-Ying;  Dong, Ying-Ying;  Ying, Hua-Zhong;  Yu, Chen-Huan
收藏  |  浏览/下载：54/0  |  提交时间：2022/01/10
Sesquiterpene lactone  Flavonoid  Cell apoptosis  ROS  JNK  FOXO1  
The Role of Apoptosis Pathway in the Cytotoxicity Induced by Fresh and Aged Zinc Oxide Nanoparticles 期刊论文
Nanoscale Research Letters, 2021, 卷号: 16
作者:  Wang,Juan;  Wang,Lei;  Zhao,Wenting;  Yu,Na;  Cheng,Meiling;  Su,Mingqin;  Hu,Jian;  Wu,Xiaoyan;  Du,Hua;  Wang,Meimei
收藏  |  浏览/下载：70/0  |  提交时间：2021/08/31
Aged zinc oxide nanoparticles  Cytotoxicity  Mechanism  Apoptosis  Transcriptomics  
Senescence associated long non-coding RNA 1 regulates cigarette smoke-induced senescence of type II alveolar epithelial cells through sirtuin-1 signaling 期刊论文
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH, 2021, 卷号: 49
作者:  Yuan, Dong;  Liu, Yuanshun;  Li, Mengyu;  Zhou, Hongbin;  Cao, Liming;  Zhang, Xiaoqin;  Li, Yaqing
收藏  |  浏览/下载：44/0  |  提交时间：2021/03/15
Chronic obstructive pulmonary disease  alveolar epithelial cells  sirtuin-1  cellular senescence  long non-coding RNA  cigarette smoke  
LncRNA GUARDIN suppresses cellular senescence through a LRP130-PGC1 alpha-FOXO4-p21-dependent signaling axis 期刊论文
EMBO REPORTS, 2020, 卷号: 21
作者:  Sun, Xuedan;  Thorne, Rick Francis;  Zhang, Xu Dong;  He, Miao;  Li, Jinming;  Feng, Shanshan;  Liu, Xiaoying;  Wu, Mian
收藏  |  浏览/下载：49/0  |  提交时间：2020/11/26
cellular senescence  GUARDIN  lncRNAs  LRP130-PGC1 alpha  p21  
Electrochemical characterization of Fe center from hemin binding with Yersinia pestis heme-protein acquisition system 期刊论文
ELECTROCHIMICA ACTA, 2019, 卷号: 298, 期号: 无, 页码: 518-524
作者:  Zhao, Yaqin;  Cui, Xiaofang;  Yang, Jing;  Yu, Lu;  Yang, Binsheng
浏览  |  Adobe PDF(1110Kb)  |  收藏  |  浏览/下载：71/38  |  提交时间：2020/03/31
Heme-protein acquisition system  Hemin  Heme  Electrochemical signals  
Is level of acetylation directly correlated to radiation sensitivity of cancer cell? 期刊论文
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 2019, 卷号: 813, 期号: 无, 页码: 13-19
作者:  Zhang, Fengqiu;  Chen, Zhu;  Shao, Changsheng;  Huang, Qing
浏览  |  Adobe PDF(3552Kb)  |  收藏  |  浏览/下载：61/21  |  提交时间：2020/03/31
Acetylation  Radiosensitivity  HeLa cells  Histone deacetylase inhibitors (HDACis)  Trichostatin A (TSA)  
Kinases Involved in Both Autophagy and Mitosis 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2017, 卷号: 18, 期号: 9, 页码: 1-15
作者:  Li, Zhiyuan;  Zhang, Xin
浏览  |  Adobe PDF(277Kb)  |  收藏  |  浏览/下载：109/50  |  提交时间：2018/08/17
Kinases  Autophagy  Mitosis  Cyclin-dependent Kinases  Aurora  Polo-like Kinases  
针对FLT3-ITD阳性急性髓细胞白血病的激酶抑制剂药物学研究 学位论文
, 合肥: 中国科学技术大学, 2017
作者:  王傲莉
Adobe PDF(7111Kb)  |  收藏  |  浏览/下载：141/0  |  提交时间：2018/01/18