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HFCAS OpenIR

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Serplulimab, a novel anti-PD-1 antibody, in patients with microsatellite instability-high solid tumours: an open-label, single-arm, multicentre, phase II trial 期刊论文
BRITISH JOURNAL OF CANCER, 2022
作者:  Qin, Shukui;  Li, Jin;  Zhong, Haijun;  Jin, Chuan;  Chen, Lili;  Yuan, Xianglin;  Fan, Qingxia;  Chen, Kehe;  Cao, Peiguo;  Xiao, Jianjun;  Jiang, Da;  Zhang, Tao;  Zhang, Hongyu;  Wang, Xicheng;  Wang, Wei;  Han, Lin;  Wang, Qingyu;  Zhu, Jun
收藏  |  浏览/下载：49/0  |  提交时间：2022/12/22
A Radiomics Nomogram Integrated With Clinic-Radiological Features for Preoperative Prediction of DNA Mismatch Repair Deficiency in Gastric Adenocarcinoma 期刊论文
FRONTIERS IN ONCOLOGY, 2022, 卷号: 12
作者:  Tong, Yahan;  Li, Jiaying;  Chen, Jieyu;  Hu, Can;  Xu, Zhiyuan;  Duan, Shaofeng;  Wang, Xiaojie;  Yu, Risheng;  Cheng, Xiangdong
收藏  |  浏览/下载：41/0  |  提交时间：2022/12/23
gastric cancer  adenocarcinoma  radiomics  tomography  X-ray computed  nomogram  DNA mismatch repair deficiency  
Utilization of genetic biomarkers testing and its associated factors in advanced colorectal cancer patients in China: a nationwide multicenter clinical epidemiological study 期刊论文
ANNALS OF TRANSLATIONAL MEDICINE, 2022
作者:  Zhang, Xi;  Lian, Xue-Mei;  Gu, Xiao-Fen;  Liu, Yin;  Feng, Chang-Yan;  Li, Li;  Xu, Hui-Fang;  Du, Jing-Chang;  Zhao, Yu-Qian;  Ma, Li;  Liu, Yun-Yong;  Huang, Juan-Xiu;  Cao, Ji;  Wang, Xiao-Hui;  Du, Ling-Bin;  Duan, Shuang-Xia;  Wang, Wen-Jun;  Fan, Yan-Ping;  Yu, Yan-Qin;  Zhang, Shao-Kai;  Shi, Ji-Hai;  Qiao, You-Lin
收藏  |  浏览/下载：59/0  |  提交时间：2022/05/16
Colorectal cancer (CRC)  biomarker  RAS  BRAF  microsatellite instability (MSI)  
TP53 Mutation Infers a Poor Prognosis and Is Correlated to Immunocytes Infiltration in Breast Cancer 期刊论文
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2021, 卷号: 9
作者:  Zhang, Ziwen;  Hao, Ran;  Guo, Qiusheng;  Zhang, Sheyu;  Wang, Xiaojia
收藏  |  浏览/下载：49/0  |  提交时间：2022/01/10
TP53  mutation  breast cancer  immunocytes infiltration  prognosis  
Additive effects of variants of unknown significance in replication repair-associated DNA polymerase genes on mutational burden and prognosis across diverse cancers 期刊论文
JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2021, 卷号: 9
作者:  Ying, Jieer;  Yang, Lin;  Yin, Jiani C.;  Xia, Guojie;  Xing, Minyan;  Chen, Xiaoxi;  Pang, Jiaohui;  Wu, Yong;  Bao, Hua;  Wu, Xue;  Shao, Yang;  Zhu, Lingjun;  Cheng, Xiangdong
收藏  |  浏览/下载：60/0  |  提交时间：2021/11/15
biomarkers  tumor  genetic markers  genome instability  Immunotherapy  translational medical research  
Computed Tomography-Based Radiomics Model to Preoperatively Predict Microsatellite Instability Status in Colorectal Cancer: A Multicenter Study 期刊论文
FRONTIERS IN ONCOLOGY, 2021, 卷号: 11
作者:  Li, Zhi;  Zhong, Qi;  Zhang, Liang;  Wang, Minhong;  Xiao, Wenbo;  Cui, Feng;  Yu, Fang;  Huang, Chencui;  Feng, Zhan
收藏  |  浏览/下载：46/0  |  提交时间：2021/08/30
computed tomography  logistic regression  microsatellite instability  colorectal cancer  AUC  
A phase 2 study of tislelizumab monotherapy in patients with previously treated, locally advanced unresectable ormetastatic microsatellite instability-high/mismatch repair deficient solid tumors. 期刊论文
JOURNAL OF CLINICAL ONCOLOGY, 2021, 卷号: 39
作者:  Li, Jian;  Xu, Ye;  Zang, Aimin;  Gao, Yunong;  Gao, Quanli;  Zhang, Yanqiao;  Wang, Dong;  Xu, Jianming;  Yuan, Ying;  Jiang, Haiping;  Ying, Jieer;  Shi, Chunmei;  Deng, Yanhong;  Wang, Jing;  Liu, Tianshu;  Huang, Yi;  Li, Zhezhen;  Wang, Huanli;  Liu, Shou;  Shen, Lin
收藏  |  浏览/下载：58/0  |  提交时间：2022/01/10
Efficacy and safety of HLX10, a novel anti-PD-1 antibody, in patients with previously treated unresectable or metastatic microsatellite instability-high or mismatch repair-deficient solid tumors: A single-arm, multicenter, phase 2 study. 期刊论文
JOURNAL OF CLINICAL ONCOLOGY, 2021, 卷号: 39
作者:  Qin, Shukui;  Li, Jin;  Zhong, Haijun;  Jin, Chuan;  Chen, Lili;  Yuan, Xianglin;  Fan, Qingxia;  Chen, Kehe;  Cao, Peiguo;  Xiao, Jianjun;  Jiang, Da;  Zhang, Tao;  Zhang, Hongyu;  Wang, Xicheng;  Wang, Wei;  Wang, Qingyu
收藏  |  浏览/下载：49/0  |  提交时间：2022/01/10
Clinicopathologic characteristics of resectable colorectal cancer with mismatch repair protein defects in Chinese population Retrospective case series and literature review 期刊论文
MEDICINE, 2020, 卷号: 99
作者:  Li, Jingjing;  Xu, Qi;  Luo, Cong;  Chen, Lei;  Ying, Jieer
收藏  |  浏览/下载：49/0  |  提交时间：2020/11/26
immunohistochemistry  left-side colon cancer  microsatellite instability  mismatch repair deficiency  right-side colon cancer  
淡水水华微囊藻毒素MC-LR的遗传毒性及其机理研究 学位论文
, 北京: 中国科学院研究生院, 2009
作者:  黄佩
Adobe PDF(1273Kb)  |  收藏  |  浏览/下载：102/25  |  提交时间：2010/04/01