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S3I-201 derivative incorporating naphthoquinone unit as effective STAT3 inhibitors: Design, synthesis and anti-gastric cancer evaluation 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2022, 卷号: 71
作者:  Li, Haobin;  Cai, Maohua;  Cao, Fei;  Yu, Dehua;  Yang, Jing;  Yu, Wenkai;  Chu, Chu;  Guan, Xiaoqing;  Qin, Jiang-Jiang;  Dong, Jinyun
收藏  |  浏览/下载：44/0  |  提交时间：2022/12/22
STAT3 inhibitor  Quinone derivative  S3I-201  Anti -gastric cancer drug  
Siglec-15 Silencing Inhibits Cell Proliferation and Promotes Cell Apoptosis by Inhibiting STAT1/STAT3 Signaling in Anaplastic Thyroid Carcinoma 期刊论文
DISEASE MARKERS, 2022, 卷号: 2022
作者:  Hou, Xiaofeng;  Chen, Chao;  He, Xiaodong;  Lan, Xiabin
收藏  |  浏览/下载：39/0  |  提交时间：2022/12/23
GSK3 beta palmitoylation mediated by ZDHHC4 promotes tumorigenicity of glioblastoma stem cells in temozolomide-resistant glioblastoma through the EZH2-STAT3 axis 期刊论文
ONCOGENESIS, 2022, 卷号: 11
作者:  Zhao, Chenggang;  Yu, Huihan;  Fan, Xiaoqing;  Niu, Wanxiang;  Fan, Junqi;  Sun, Suling;  Gong, Meiting;  Zhao, Bing;  Fang, Zhiyou;  Chen, Xueran
收藏  |  浏览/下载：33/0  |  提交时间：2022/12/23
Inhibition of STAT3 Signaling Pathway by Terphenyllin Suppresses Growth and Metastasis of Gastric Cancer 期刊论文
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13
作者:  Yu, Dehua;  Qi, Simin;  Guan, Xiaoqing;  Yu, Wenkai;  Yu, Xuefei;  Cai, Maohua;  Li, Qinglin;  Wang, Weiyi;  Zhang, Weidong;  Qin, Jiang-Jiang
收藏  |  浏览/下载：34/0  |  提交时间：2022/12/23
STAT3  inhibitor  natural product  gastric cancer  terphenyllin  
Renal cell carcinoma-derived exosomes deliver lncARSR to induce macrophage polarization and promote tumor progression via STAT3 pathway 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2022, 卷号: 18
作者:  Zhang, Wei;  Zheng, Xiaoxiao;  Yu, Yisong;  Zheng, Li;  Lan, Jiahua;  Wu, Ying;  Liu, Hao;  Zhao, An;  Huang, Hang;  Chen, Wei
收藏  |  浏览/下载：48/0  |  提交时间：2022/12/22
Tumor-derived exosomes  Renal cell carcinoma (RCC)  Macrophage polarization  lncARSR  STAT3  
Recent Update on Development of Small-Molecule STAT3 Inhibitors for Cancer Therapy: From Phosphorylation Inhibition to Protein Degradation 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64
作者:  Dong, Jinyun;  Cheng, Xiang-Dong;  Zhang, Wei-Dong;  Qin, Jiang-Jiang
收藏  |  浏览/下载：61/0  |  提交时间：2021/08/31
miR-221-3p and miR-222-3p regulate the SOCS3/STAT3 signaling pathway to downregulate the expression of NIS and reduce radiosensitivity in thyroid cancer 期刊论文
EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2021, 卷号: 21
作者:  Ye, Ting;  Zhong, Lili;  Ye, Xuemei;  Liu, Jie;  Li, Linfa;  Yi, Heqing
收藏  |  浏览/下载：63/0  |  提交时间：2021/06/15
differentiated thyroid cancer  microRNA-221  microRNA-222  suppressor of cytokine signaling 3  solute carrier family 5 member 5  radiosensitivity  
Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation 期刊论文
Stem Cell Research & Therapy, 2021, 卷号: 12
作者:  Fan,Xiaoqing;  Yang,Haoran;  Zhao,Chenggang;  Hu,Lizhu;  Wang,Delong;  Wang,Ruiting;  Fang,Zhiyou;  Chen,Xueran
收藏  |  浏览/下载：43/0  |  提交时间：2021/11/29
Local anesthetics  Glioblastoma stem cells  Self-renewal  ZDHHC15  GP130  STAT3  
WNT2-Mediated FZD2 Stabilization Regulates Esophageal Cancer Metastasis via STAT3 Signaling 期刊论文
FRONTIERS IN ONCOLOGY, 2020, 卷号: 10
作者:  Fu, Yufei;  Zheng, Qi;  Mao, Yingying;  Jiang, Xiyi;  Chen, Xin;  Liu, Pei;  Lv, Bin;  Huang, Tuxiong;  Yang, Jiao;  Cheng, Yongran;  Dai, Xiaoyi;  Dai, Chunyan;  Wang, Xi;  Yin, Yifei;  Song, Tengjiao;  Jin, Weiyang;  Zou, Chang;  Chen, Tianhui;  Fu, Li;  Chen, Zhe
收藏  |  浏览/下载：36/0  |  提交时间：2020/10/26
esophageal squamous cell carcinoma (ESCC)  metastasis  WNT2  FZD2  ubiquitination  STAT3signaling  
Discovery of 2-(4-Chloro-3-(trifluoromethyl)phenyl)-N-(4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)acetamide (CHMFL-KIT-64) as a Novel Orally Available Potent Inhibitor against Broad-Spectrum Mutants of 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019
作者:  Yun Wu;  Beilei Wang;  Junjie Wang;  Qi S(亓爽);  Fengming Zou;  Ziping Qi;  Feiyang Liu;  Wenchao Wang;  Qingsong Liu;  Jing Liu
浏览  |  Adobe PDF(5207Kb)  |  收藏  |  浏览/下载：131/66  |  提交时间：2020/10/20