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HFCAS OpenIR

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Drug-resistant HER2-positive breast cancer: Molecular mechanisms and overcoming strategies 期刊论文
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13
作者:  Wu, Xiaofan;  Yang, Hongjian;  Yu, Xingfei;  Qin, Jiang-Jiang
收藏  |  浏览/下载：51/0  |  提交时间：2022/12/22
HER2  breast cancer  targeted therapy  drug resistance  overcoming strategies  
Beyond Blocking: Engineering RNAi-Mediated Targeted Immune Checkpoint Nanoblocker Enables T-Cell-lndependent Cancer Treatment 期刊论文
ACS NANO, 2020, 卷号: 14
作者:  Han, Xiaoyan;  Wang, Linlin;  Li, Ting;  Zhang, Jiahui;  Zhang, Dailiang;  Li, Jili;  Xia, Yinghao;  Liu, Yanlan;  Tan, Weihong
收藏  |  浏览/下载：52/0  |  提交时间：2021/03/15
immune checkpoint blockade  RNAi engineering  nanostructure  NSCLC  cancer immunotherapy  
Multi-Enzymatic Cascade One-Pot Biosynthesis of 3 '-Sialyllactose Using Engineered Escherichia coli 期刊论文
MOLECULES, 2020
作者:  Li, Zhongkui;  Ni, Zhijian;  Chen, Xiangsong;  Wang, Gang;  Wu, Jinyong;  Yao, Jianming
浏览  |  Adobe PDF(3364Kb)  |  收藏  |  浏览/下载：80/31  |  提交时间：2020/11/30
multi-enzymes  biosynthesis  3 '-SL  cofactor regeneration  
Discovery of (E)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)propanamide (CHMFL-ABL-121) as a highly potent ABL kinase inhibitor capable of overcoming a variety of ABL mutants including T315I for chronic myeloid leukemia 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 160, 页码: 61-81
作者:  Liu, Xuesong;  Wang, Beilei;  Chen, Cheng;  Jiang, Zongru;  Hu, Chen;  Wu, Hong;  Zhang, Yicong;  Liu, Xiaochuan;  Wang, Wenliang;  Wang, Junjie;  Hu, Zhenquan;  Wang, Aoli;  Huang, Tao;  Liu, Qingwang;  Wang, Wei;  Wang, Li;  Wang, Wenchao;  Ren, Tao;  Li, Lili;  Xia, Ruixiang;  Ge, Jian;  Liu, Qingsong;  Liu, Jing
Adobe PDF(4593Kb)  |  收藏  |  浏览/下载：195/104  |  提交时间：2019/01/11
ABL kinase  Kinase inhibitor  ABL mutant  CML  
Poly (amidoamine) (PAMAM) dendrimer mediated delivery of drug and pDNA/siRNA for cancer therapy 期刊论文
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2018, 卷号: 546, 期号: 1-2, 页码: 215-225
作者:  Li, Jun;  Liang, Huamin;  Liu, Jing;  Wang, Ziyuan
浏览  |  Adobe PDF(3199Kb)  |  收藏  |  浏览/下载：214/130  |  提交时间：2018/10/10
Nanostructures for pH-sensitive Drug Delivery and Magnetic Resonance Contrast Enhancement Systems 期刊论文
CURRENT MEDICINAL CHEMISTRY, 2018, 卷号: 25, 期号: 25, 页码: 3036-3057
作者:  Sun, Xiao;  Zhang, Guilong;  Wu, Zhengyan
浏览  |  Adobe PDF(4176Kb)  |  收藏  |  浏览/下载：93/47  |  提交时间：2019/12/25
pH-responsive  magnetic resonance contrast agents  drug delivery systems  contrast enhancement  controlled release  cancer diagnosis and chemotherapy  
Improving GRN re-construction by mining hidden regulatory signals 期刊论文
IET SYSTEMS BIOLOGY, 2017, 卷号: 11, 期号: 6, 页码: 174-181
作者:  Shi, Ming;  Shen, Weiming;  Chong, Yanwen;  Wang, Hong-Qiang
浏览  |  Adobe PDF(4496Kb)  |  收藏  |  浏览/下载：152/40  |  提交时间：2018/08/17
Genetics  Molecular Biophysics  Biology Computing  Singular Value Decomposition  Sensitivity Analysis  Gene Regulatory Networks  Gene Expression  Hidden Regulatory Signal Mining  Transcription Factor  Dictionary Learning Model K-svd  Receiver Operating Characteristic Curves  
Strategies for evaluating performance of flexibility in product recovery system 期刊论文
INTERNATIONAL JOURNAL OF PRODUCTION RESEARCH, 2016, 卷号: 54, 期号: 10, 页码: 2895-2906
作者:  Madaan, Jitender;  Chan, Felix T. S.;  Niu, Ben
浏览  |  Adobe PDF(712Kb)  |  收藏  |  浏览/下载：100/49  |  提交时间：2017/11/10
Reverse Supply Chains  Performance  Flexibility  Product Recovery System  
Energy-efficient Bio-inspired Gait Planning and Control for Biped Robot Based on Human Locomotion Analysis 期刊论文
JOURNAL OF BIONIC ENGINEERING, 2016, 卷号: 13, 期号: 2, 页码: 271-282
作者:  Zhu, Hongbo;  Luo, Minzhou;  Mei, Tao;  Zhao, Jianghai;  Li, Tao;  Guo, Fayong
浏览  |  Adobe PDF(2625Kb)  |  收藏  |  浏览/下载：180/97  |  提交时间：2017/11/10
Motion Capture  Allowable Zero Moment Point (Zmp) Variation Region (Azr)  Bio-inspired Gait Planning (Bgp)  Humanoid Robot  
Motion planning for humanoid robot dynamically stepping over consecutive large obstacles 期刊论文
INDUSTRIAL ROBOT-AN INTERNATIONAL JOURNAL, 2016, 卷号: 43, 期号: 2, 页码: 204-220
作者:  Guo, Fayong;  Mei, Tao;  Luo, Minzhou;  Ceccarelli, Marco;  Zhao, Ziyi;  Li, Tao;  Zhao, Jianghai
浏览  |  Adobe PDF(1109Kb)  |  收藏  |  浏览/下载：141/89  |  提交时间：2016/12/15
Consecutive Obstacles Stepping Over  Feasibility Analysis  Full-sized Humanoid Robot  Motion Planning