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HFCAS OpenIR

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The reversal of anti-HER2 resistance in advanced HER2-positive breast cancer using apatinib: two cases reports and literature review 期刊论文
TRANSLATIONAL CANCER RESEARCH, 2022
作者:  He, Libin;  Shen, Xiabo;  Liu, Yiyuan;  Gao, Lu;  Wu, Jiayi;  Yu, Chang;  Li, Guangliang;  Wang, Xiaojia;  Shao, Xiying
收藏  |  浏览/下载：41/0  |  提交时间：2022/12/23
Advanced human epidermal growth factor receptor 2-positive breast cancer (advanced HER2-positive breast cancer)  apatinib  case report  
Discovery of 4-((N-(2-(dimethylamino)ethyl)acrylamido)methyl)-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide (CHMFL-PDGFR-159) as a highly selective type II PDGFR alpha kinase inhibitor for PDGFR alpha driving chronic eosinophilic leukemia 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 150, 期号: 无, 页码: 366-384
作者:  Wang, Qiang;  Liu, Feiyang;  Qi, Shuang;  Qi, Ziping;  Yan, Xiao-E.;  Wang, Beilei;  Wang, Aoli;  Wang, Wei;  Chen, Cheng;  Liu, Xiaochuan;  Jiang, Zongru;  Hu, Zhenquan;  Wang, Li;  Wang, Wenchao;  Ren, Tao;  Zhang, Shanchun;  Yun, Cai-Hong;  Liu, Qingsong;  Liu, Jing
浏览  |  Adobe PDF(5108Kb)  |  收藏  |  浏览/下载：596/506  |  提交时间：2019/06/10
PDGFR kinase  Type II inhibitor  Kinase inhibitor  CEL  
Discovery of 4-((N-(2-(dimethylamino)ethyl)acrylamido)methyl)-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide (CHMFL-PDGFR-159) as a highly selective type II PDGFRα kinase inhibi 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018
作者:  Qiang Wang;  Feiyang Liu;  Qi S(亓爽);  Ziping Qi;  Beilei Wang;  Aoli Wang;  Zongru Jiang;  Wenchao Wang;  Qingsong Liu;  Jing Liu
浏览  |  Adobe PDF(5108Kb)  |  收藏  |  浏览/下载：132/54  |  提交时间：2020/10/20
基于高通量功能细胞库筛选的新型选择性激酶小分子抑制剂的发现及生物机制研究 学位论文
, 合肥: 中国科学技术大学, 2016
作者:  刘飞扬
Adobe PDF(5845Kb)  |  收藏  |  浏览/下载：16/0  |  提交时间：2018/01/18
Expression of VEGFR2 and NRP-1 in non-small cell lung cancer and their clinical significance 期刊论文
CHINESE JOURNAL OF CANCER RESEARCH, 2014, 卷号: 26
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收藏  |  浏览/下载：35/0  |  提交时间：2020/10/26
ENDOTHELIAL GROWTH-FACTOR  TUMOR-CELLS  CARCINOMA  NEUROPILIN-1  RECEPTORS  VEGF(165)  Non-small cell lung cancer (NSCLC)  vascular endothelial growth factor receptor 2 (VEGFR2)  neuropilin-1 (NRP-1)  fluorescence in situ hybridization (FISH)