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Identification of chitin synthase activator in Aspergillus niger and its application in citric acid fermentation 期刊论文
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2022
作者:  Jiang, Chunxu;  Wang, Han;  Liu, Menghan;  Wang, Li;  Yang, Ruwen;  Wang, Peng;  Lu, Zongmei;  Zhou, Yong;  Zheng, Zhiming;  Zhao, Genhai
收藏  |  浏览/下载：38/0  |  提交时间：2022/12/22
Chitin synthases activator  Citric acid  Morphology  Aspergillus niger  RNAi  Synergistic effect  
Enhancement of Vitamin K2 Efflux in Bacillus subtilis Natto via a Potential Protein Receptor for Increased Yield 期刊论文
JOURNAL OF FOOD QUALITY, 2022, 卷号: 2022
作者:  Li, Chu;  Wang, Han;  Ma, Guoliang;  Wang, Li;  Zheng, Zhiming;  Zhao, Genhai;  Wang, Peng
收藏  |  浏览/下载：45/0  |  提交时间：2022/12/22
Rational Design by Structural Biology of Industrializable, Long-Acting Antihyperglycemic GLP-1 Receptor Agonists 期刊论文
PHARMACEUTICALS, 2022, 卷号: 15
作者:  Sun, Lei;  Zheng, Zhi-Ming;  Shao, Chang-Sheng;  Zhang, Zhi-Yong;  Li, Ming-Wei;  Wang, Li;  Wang, Han;  Zhao, Gen-Hai;  Wang, Peng
收藏  |  浏览/下载：48/0  |  提交时间：2022/12/22
glucagon-like peptide-1  GLP-1 receptor agonist  functional protein design  molecular dynamics simulation  long-acting antihyperglycemic  
Bottom-up synthetic biology approach for improving the efficiency of menaquinone-7 synthesis in Bacillus subtilis 期刊论文
Microbial Cell Factories, 2022, 卷号: 21
作者:  Ding,Xiumin;  Zheng,Zhiming;  Zhao,Genhai;  Wang,Li;  Wang,Han;  Yang,Qiang;  Zhang,Mengxue;  Li,Luyao;  Wang,Peng
收藏  |  浏览/下载：34/0  |  提交时间：2022/12/22
Menaquinone-7  Bacillus subtilis  Synthetic biology  Metabolic engineering  Cofactor engineering  NADH kinase  
Vitamin K2 Modulates Mitochondrial Dysfunction Induced by 6-Hydroxydopamine in SH-SY5Y Cells via Mitochondrial Quality-Control Loop 期刊论文
NUTRIENTS, 2022, 卷号: 14
作者:  Tang, Hengfang;  Zheng, Zhiming;  Wang, Han;  Wang, Li;  Zhao, Genhai;  Wang, Peng
收藏  |  浏览/下载：59/0  |  提交时间：2022/05/16
vitamin K2  apoptosis  ROS  mitochondrial dysfunction  mitophagy  mitochondrial biogenesis  mitochondrial quality-control loop  PINK1  Parkin signaling pathway  
Engineering microbial consortia of Elizabethkingia meningoseptica and Escherichia coli strains for the biosynthesis of vitamin K2 期刊论文
Microbial Cell Factories, 2022, 卷号: 21
作者:  Yang,Qiang;  Zheng,Zhiming;  Zhao,Genhai;  Wang,Li;  Wang,Han;  Ding,XiuMin;  Jiang,Chunxu;  Li,Chu;  Ma,Guoliang;  Wang,Peng
收藏  |  浏览/下载：76/0  |  提交时间：2022/05/16
Vitamin K2  Microbial consortia  Metabolic engineering  Elizabethkingia meningoseptica  
Cloning and functional characterization of the geranylgeranyl diphosphate synthase(GGPPS)from Elizabethkingia meningoseptica sp.F2 期刊论文
PROTEIN EXPRESSION AND PURIFICATION, 2022, 卷号: 189
作者:  Yang, Qiang;  Zheng, Zhiming;  Zhao, Genhai;  Wang, Li;  Wang, Han;  Ni, Wenfeng;  Sun, Xiaowen;  Zhang, Mengxue;  Tang, Hengfang;  Wang, Peng
收藏  |  浏览/下载：63/0  |  提交时间：2021/11/29
Elizabethkingia meningoseptica  Geranylgeranyl diphosphate synthase  Soluble expression  MK-4  
A study of hydrophobins-modified menaquinone-7 on osteoblastic cells differentiation 期刊论文
MOLECULAR AND CELLULAR BIOCHEMISTRY, 2021
作者:  Tang, Hengfang;  Zhu, Zhu;  Zheng, Zhiming;  Wang, Han;  Li, Chu;  Wang, Li;  Zhao, Genhai;  Wang, Peng
收藏  |  浏览/下载：53/0  |  提交时间：2021/03/15
Menaquinone-7  Hydrophobins  Alkaline phosphatase  Osteocalcin  OPG  RANKL  Mitochondria  
Synthesis of the carboxymethyl cellulose magnetic nanoparticles for efficient immobilization of prenyltransferase NovQ 期刊论文
CARBOHYDRATE POLYMERS, 2020, 卷号: 235
作者:  Ni, Wenfeng;  Zheng, Zhiming;  Liu, Hui;  Wang, Peng;  Wang, Li;  Wang, Han;  Sun, Xiaowen;  Yang, Qiang;  Tang, Hengfang;  Zhao, Genhai
收藏  |  浏览/下载：64/0  |  提交时间：2020/11/26
Carboxymethyl cellulose  Magnetic nanoparticles  Prenyltransferase NovQ  Immobilization  Prenylated activity  
Combining mutagenesis on Glu281 of prenyltransferase NovQ and metabolic engineering strategies for the increased prenylated activity towards menadione 期刊论文
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2020
作者:  Ni, Wenfeng;  Zheng, Zhiming;  Liu, Hui;  Wang, Peng;  Wang, Han;  Sun, Xiaowen;  Yang, Qiang;  Fang, Zhiwei;  Tang, Hengfang;  Zhao, Genhai
收藏  |  浏览/下载：215/0  |  提交时间：2020/11/26
Prenyltransferase NovQ  Menadione hydroquinol  Site-directed mutagenesis  Mevalonate pathway  Metabolic engineering