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Duplex real-time fluorescent recombinase polymerase amplification for the rapid and sensitive detection of two resistance genes in drug-resistant Staphylococcus aureus 期刊论文
JOURNAL OF MICROBIOLOGICAL METHODS, 2022, 卷号: 202
作者:  Shi, Zhonglin;  Li, Yanan;  Hu, Anzhong;  Cui, Junsheng;  Shao, Min;  Zhu, Ling;  Yang, Ke;  Liu, Yong;  Deng, Guoqing;  Zhu, Cancan
收藏  |  浏览/下载:38/0  |  提交时间:2022/12/23
Drug -resistant Staphylococcus aureus  ermA  mecA  Recombinase polymerase amplification  Resistance genes  
Drug-resistant HER2-positive breast cancer: Molecular mechanisms and overcoming strategies 期刊论文
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13
作者:  Wu, Xiaofan;  Yang, Hongjian;  Yu, Xingfei;  Qin, Jiang-Jiang
收藏  |  浏览/下载:51/0  |  提交时间:2022/12/22
HER2  breast cancer  targeted therapy  drug resistance  overcoming strategies  
CHMFL-26 is a highly potent irreversible HER2 inhibitor for use in the treatment of HER2-positive and HER2-mutant cancers 期刊论文
ACTA PHARMACOLOGICA SINICA, 2022
作者:  Cao, Jiang-yan;  Qi, Shuang;  Wu, Hong;  Wang, Ao-li;  Liu, Qing-wang;  Li, Xi-xiang;  Wang, Bei-lei;  Ge, Juan;  Zou, Feng-ming;  Chen, Cheng;  Wang, Jun-jie;  Hu, Chen;  Liu, Jing;  Wang, Wen-chao;  Liu, Qing-song
收藏  |  浏览/下载:104/0  |  提交时间:2022/03/28
HER2  breast cancers  gastric cancers  irreversible inhibitor  drug resistance  
Out-of-the-Box Nanocapsules Packed with On-Demand Hydrophobic Anticancer Drugs for Lung Targeting, Esterase Triggering, and Synergy Therapy 期刊论文
ADVANCED HEALTHCARE MATERIALS, 2021
作者:  Zhao, Di;  Jiang, Kai;  Wang, Yuqi;  Cheng, Jin;  Mo, Fangli;  Luo, Tao;  Guo, Yuanyuan;  Zhang, Chuan;  Song, Jie
收藏  |  浏览/下载:263/0  |  提交时间:2021/03/15
controllable esterase response  high loading efficiency  lung targeting  multi-drug resistance  universal drug encapsulation  
Research Progress on Long Non-coding RNAs and Drug Resistance of Breast Cancer 期刊论文
CLINICAL BREAST CANCER, 2020, 卷号: 20
作者:  Zhang, Xiping;  Yang, Hongjian
收藏  |  浏览/下载:32/0  |  提交时间:2020/10/26
Breast cancer  Drug resistance  Epithelial to mesenchymal transitions (EMT)  Long non-coding ribonucleic acids (LncRNAs)  Molecular mechanisms  
A nanomicelle with miR-34a and doxorubicin reverses the drug resistance of cisplatin in esophageal carcinoma cells by inhibiting SIRT1 signal pathway 期刊论文
TRANSLATIONAL CANCER RESEARCH, 2020, 卷号: 9
作者:  Fang, Jun;  Wang, Yuezhen;  Wang, Zhun;  Xie, Tieming;  Yan, Fengqin;  Wang, Lei;  Hua, Jianfeng;  Wang, Fangzheng;  Fu, Zhenfu;  Ye, Zhimin
收藏  |  浏览/下载:49/0  |  提交时间:2020/11/26
Nanomicelle  miR-34a  esophageal carcinoma (EC)  p53  SIRT1  drug resistance  
Targeting slug-mediated non-canonical activation of c-Met to overcome chemo-resistance in metastatic ovarian cancer cells 期刊论文
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9
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收藏  |  浏览/下载:31/0  |  提交时间:2020/10/26
EPITHELIAL-MESENCHYMAL TRANSITION  TUMOR-GROWTH  HETEROGENEITY  AMPLIFICATION  CONTRIBUTES  PROGRESSION  CARCINOMA  REVEALS  PATHWAY  SNAIL  Slug  c-Met  Drug resistance  Ovarian cancer  XL184  
Repurposing cabozantinib to GISTs: Overcoming multiple imatinib-resistant cKIT mutations including gatekeeper and activation loop mutants in GISTs preclinical models 期刊论文
CANCER LETTERS, 2019, 页码: 105-114
作者:  Lu, Tingting;  Chen, Cheng;  Wang, Aoli;  Jiang, Zongru;  Qi, Ziping;  Hu, Zhenquan;  Hu, Chen;  Liu, Feiyang;  Wang, Wenliang;  Wu, Hong;  Wang, Beilei;  Wang, Li;  Qi, Shuang;  Wu, Jiaxin;  Wang, Wenchao;  Tang, Jun;  Yan, Hezhong;  Bai, Mingfeng;  Liu, Qingsong;  Liu, Jing
收藏  |  浏览/下载:26/0  |  提交时间:2020/07/14
cKIT T670I mutant  Activation loop mutants  Drug resistance  
Discovery and characterization of a novel irreversible EGFR mutants selective and potent kinase inhibitor CHMFL-EGFR-26 with a distinct binding mode 期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 11, 页码: 18359-18372
作者:  Hu, Chen;  Wang, Aoli;  Wu, Hong;  Qi, Ziping;  Li, Xixiang;  Yan, Xiao-E;  Chen, Cheng;  Yu, Kailin;  Zou, Fengming;  Wang, Wenchao;  Wang, Wei;  Wu, Jiaxin;  Liu, Juan;  Wang, Beilei;  Wang, Li;  Ren, Tao;  Zhang, Shanchun;  Yun, Cai-Hong;  Liu, Jing;  Liu, Qingsong
浏览  |  Adobe PDF(6153Kb)  |  收藏  |  浏览/下载:183/48  |  提交时间:2018/07/04
Egfr  Egfrt790m  Nsclc  Kinase Inhibitors  Drug Resistance  
The formation of intracellular nanoparticles correlates with cisplatin resistance 期刊论文
SCIENCE CHINA-MATERIALS, 2015, 卷号: 58
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收藏  |  浏览/下载:17/0  |  提交时间:2020/10/26
GLUTATHIONE-S-TRANSFERASE  SQUAMOUS-CELL CARCINOMA  LOCALLY ADVANCED HEAD  PLATINUM NANOPARTICLES  NECK-CANCER  MOLECULAR-MECHANISMS  DRUG-RESISTANCE  CHEMOTHERAPY  CYTOTOXICITY  NANOMATERIALS