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9.4 T static magnetic field ameliorates imatinib mesylate-induced toxicity and depression in mice 期刊论文
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2022
作者:  Tian, Xiaofei;  Wang, Chentai;  Yu, Biao;  Fan, Yixiang;  Zhang, Lei;  Zhang, Xin
收藏  |  浏览/下载：56/0  |  提交时间：2022/12/22
Static magnetic fields (SMFs)  Imatinib mesylate  Gastrointestinal stromal tumor (GIST)  Drug toxicity  Depression  
Repurposing of Kinase Inhibitors for Treatment of COVID-19 期刊论文
PHARMACEUTICAL RESEARCH, 2020, 卷号: 37
作者:  Weisberg, Ellen;  Parent, Alexander;  Yang, Priscilla L.;  Sattler, Martin;  Liu, Qingsong;  Liu, Qingwang;  Wang, Jinhua;  Meng, Chengcheng;  Buhrlage, Sara J.;  Gray, Nathanael;  Griffin, James D.
收藏  |  浏览/下载：42/0  |  提交时间：2020/10/26
Coronavirus  SARS-CoV-2  SARS-CoV  MERS-CoV  kinase inhibitors  pharmacokinetics  antiviral therapy  COVID-19  
c-Abl inhibition mitigates diet-induced obesity through improving insulin sensitivity of subcutaneous fat in mice 期刊论文
DIABETOLOGIA, 2017, 卷号: 60, 期号: 5, 页码: 900-910
作者:  Wu, Rong;  Sun, Jian-guang;  Wang, Ji-qiu;  Li, Binhua;  Liu, Qingsong;  Ning, Guang;  Jin, Wanzhu;  Yuan, Zengqiang
收藏  |  浏览/下载：47/0  |  提交时间：2018/07/26
JQ1 与ABT-263 协同治疗N-Myc 扩增的小细胞肺癌的研究 学位论文
, 合肥: 中国科学技术大学, 2017
作者:  王伙刚
Adobe PDF(11790Kb)  |  收藏  |  浏览/下载：47/1  |  提交时间：2018/01/18
Discovery of N-((1-(4-(3-(3-((6,7-Dimethoxyquinolin-3-yl)oxy)phenyl)ureido)-2-(trifluoromethyl)phenyl)piperidin-4-yl)methyl)propionamide (CHMFL-KIT-8140) as a Highly Potent Type II Inhibitor Capable of Inhibiting the T670I "Gatekeeper" Mutant of cKIT Kinase 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 18, 页码: 8456-8472
作者:  Li, Binhua;  Wang, Aoli;  Liu, Juan;  Qi, Ziping;  Liu, Xiaochuan;  Yu, Kailin;  Wu, Hong;  Chen, Cheng;  Hu, Chen;  Wang, Wenchao;  Wu, Jiaxin;  Hu, Zhenquan;  Ye, Ling;  Zou, Fengming;  Liu, Feiyang;  Wang, Beilei;  Wang, Li;  Ren, Tao;  Zhang, Shaojuan;  Bai, Mingfeng;  Zhang, Shanchun;  Liu, Jing;  Liu, Qingsong
浏览  |  Adobe PDF(2856Kb)  |  收藏  |  浏览/下载：1414/1300  |  提交时间：2017/11/21
Discovery and characterization of a novel potent type II native and mutant BCR-ABL inhibitor (CHMFL-074) for Chronic Myeloid Leukemia (CML) 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 29, 页码: 45562-45574
作者:  Liu, Feiyang;  Wang, Beilei;  Wang, Qiang;  Qi, Ziping;  Chen, Cheng;  Kong, Lu-Lu;  Chen, Ji-Yun;  Liu, Xiaochuan;  Wang, Aoli;  Hu, Chen;  Wang, Wenchao;  Wang, Huiping;  Wu, Fan;  Ruan, Yanjie;  Qi, Shuang;  Liu, Juan;  Zou, Fengming;  Hu, Zhenquan;  Wang, Wei;  Wang, Li;  Zhang, Shanchun;  Yun, Cai-Hong;  Zhai, Zhimin;  Liu, Jing;  Liu, Qingsong
浏览  |  Adobe PDF(8054Kb)  |  收藏  |  浏览/下载：258/203  |  提交时间：2017/11/21
Bcr-abl  Pdgfr  Chronic Myeloid Leukemia  Kinase Inhibitor  
Discovery of N-(34(1-lsonicotinoylpiperidin-4-yl)oxy)-4methylpheny1)-3-(trifluoromethyl)benzamide (CHMFL-KIT-110) as a Selective, Potent, and Orally Available Type II c-KIT Kinase Inhibitor for Gastrointestinal Stromal Tumors (GISTs) 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 8, 页码: 3964-3979
作者:  Wang, Qang;  Liu, Feiyang;  Wang, Beilei;  Zou, Fengming;  Chen, Cheng;  Liu, Xiaochuan;  Wang, Aoli;  Qi, Shuang;  Wang, Wenchao;  Qi, Ziping;  Zhao, Zheng;  Hu, Zhenquan;  Wang, Wei;  Wang, Li;  Zhang, Shanchun;  Wang, Yuexiang;  Liu, Jing;  Liu, Qingsong
浏览  |  Adobe PDF(10221Kb)  |  收藏  |  浏览/下载：133/78  |  提交时间：2017/11/10
基于高通量功能细胞库筛选的新型选择性激酶小分子抑制剂的发现及生物机制研究 学位论文
, 合肥: 中国科学技术大学, 2016
作者:  刘飞扬
Adobe PDF(5845Kb)  |  收藏  |  浏览/下载：16/0  |  提交时间：2018/01/18
Mitochondrial reactive oxygen species regulate TGF-beta signaling 期刊论文
J. Biol. Chem., 2012, 卷号: 30
作者:  Manu Jain;  Stephanie Rivera;  Elena A.Monclus;  Lauren Synenki;  Aaron Zirk;  James Eisenbart;  Carol Feghali-Bostwick;  Gokhan M. Mutlu;  G. R. Scott Budinger;  Navdeep S. Chandel
Adobe PDF(8424Kb)  |  收藏  |  浏览/下载：274/126  |  提交时间：2014/01/22
Development of multiple myeloma in a patient with gastrointestinal stromal tumor treated with imatinib mesylate: A case report 期刊论文
WORLD JOURNAL OF GASTROENTEROLOGY, 2007, 卷号: 13
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收藏  |  浏览/下载：31/0  |  提交时间：2020/10/26
SYNCHRONOUS OCCURRENCE  ADENOCARCINOMA  STOMACH  GIST  gastrointestinal stromal tumor  multiple myeloma  imatinib mesylate