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Non-thermal plasma induces apoptosis accompanied by protective autophagy via activating JNK/Sestrin2 pathway 期刊论文
JOURNAL OF PHYSICS D-APPLIED PHYSICS, 2020, 卷号: 53
Authors:  Ma, Jie;  Yu, K. N.;  Zhang, Hao;  Nie, Lili;  Cheng, Cheng;  Cui, Shujun;  Yang, Miaomiao;  Chen, Guodong;  Han, Wei
Favorite  |  View/Download:52/0  |  Submit date:2020/10/28
non-thermal plasma  apoptosis  protective autophagy  c-JUN N-terminal kinase  Sestrin2  
ULK1 inhibitor induces spindle microtubule disorganization and inhibits phosphorylation of Ser10 of histone H3 期刊论文
FEBS OPEN BIO, 2020, 卷号: 10
Authors:  Ji, Xinmiao;  Zhang, Xin;  Li, Zhiyuan
Favorite  |  View/Download:44/0  |  Submit date:2020/12/07
autophagy  mitosis  MRT68921  polyploidy  SBI‐  0206965  ULK1 inhibitor  
The dual HDAC-PI3K inhibitor CUDC-907 displays single-agent activity and synergizes with PARP inhibitor olaparib in small cell lung cancer 期刊论文
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2020, 卷号: 39
Authors:  Ma, Liying;  Bian, Xing;  Lin, Wenchu
Favorite  |  View/Download:45/0  |  Submit date:2020/11/30
SCLC  PI3K  HDAC  CUDC-907  PARP1  Olaparib  DSB repair  Combination treatment  
Efficacy of Pyrotinib in HER2-Overexpressing Salivary Duct Carcinoma With Lung Metastasis: A Case Report 期刊论文
FRONTIERS IN ONCOLOGY, 2020, 卷号: 10
Authors:  Yang, Zi-yan;  Huang, Jia-huan;  Chen, Bo;  Xu, Chun-wei;  Lei, Lei;  Wang, Xiao-jia;  Fang, Mei-yu
Favorite  |  View/Download:0/0  |  Submit date:2020/11/30
salivary duct carcinoma  tyrosine kinase inhibitor  pyrotinib  HER2 positive  targeted  
An ultra-long circulating nanoparticle for reviving a highly selective BCR-ABL inhibitor in long-term effective and safe treatment of chronic myeloid leukemia 期刊论文
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2020, 卷号: 29
Authors:  Fu, Liyi;  Zou, Fengming;  Liu, Qingwang;  Wang, Beilei;  Wang, Junqing;  Liang, Huamin;  Liang, Xiaofei;  Liu, Jing;  Shi, Jinjun;  Liu, Qingsong
Favorite  |  View/Download:0/0  |  Submit date:2020/11/30
Chronic myeloid leukemia  BCR-ABL  Long-circulating nanoparticle  Drug delivery  
Discovery of a highly potent and selective Bruton's tyrosine kinase inhibitor avoiding impairment of ADCC effects for B-cell non-Hodgkin lymphoma 期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2020, 卷号: 5
Authors:  Liu, Juan;  Liang, Qianmao;  Wang, Aoli;  Zou, Fengming;  Qi, Ziping;  Yu, Kailin;  Liu, Qingwang;  Chen, Cheng;  Liu, Jing;  Liu, Qingsong
Favorite  |  View/Download:0/0  |  Submit date:2020/11/30
Downregulation of CDC20 Increases Radiosensitivity through Mcl-1/p-Chk1-Mediated DNA Damage and Apoptosis in Tumor Cells 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 卷号: 21
Authors:  Gao, Yang;  Wen, Pengbo;  Chen, Bin;  Hu, Guanshuo;  Wu, Lijun;  Xu, An;  Zhao, Guoping
Favorite  |  View/Download:0/0  |  Submit date:2020/11/30
CDC20  radiotherapy  Mcl-1  p-Chk1  mitochondrial-dependent apoptotic pathway  
The deep learning model combining CT image and clinicopathological information for predicting ALK fusion status and response to ALK-TKI therapy in non-small cell lung cancer patients 期刊论文
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2020
Authors:  Song, Zhengbo;  Liu, Tianchi;  Shi, Lei;  Yu, Zongyang;  Shen, Qing;  Xu, Mengdi;  Huang, Zhangzhou;  Cai, Zhijian;  Wang, Wenxian;  Xu, Chunwei;  Sun, Jingjing;  Chen, Ming
Favorite  |  View/Download:2/0  |  Submit date:2020/10/26
Deep learning model  Anaplastic lymphoma kinase  Computed tomography  Non-small cell lung cancer  
Pharmacologically inhibiting phosphoglycerate kinase 1 for glioma with NG52 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020
Authors:  Wang, Wen-liang;  Jiang, Zong-ru;  Hu, Chen;  Chen, Cheng;  Hu, Zhen-quan;  Wang, Ao-li;  Wang, Li;  Liu, Jing;  Wang, Wen-chao;  Liu, Qing-song
Favorite  |  View/Download:0/0  |  Submit date:2020/11/26
PGK1  NG52  kinase inhibitor  Warburg effect  glioma  
Antagonizing CDK8 Sensitizes Colorectal Cancer to Radiation Through Potentiating the Transcription of e2f1 Target Gene apaf1 期刊论文
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2020, 卷号: 8
Authors:  Chen, Bin;  Wen, Pengbo;  Hu, Guanshuo;  Gao, Yang;  Qi, Xiaojing;  Zhu, Kaili;  Chen, Shaopeng;  Wu, Lijun;  Xu, An;  Zhao, Guoping
Favorite  |  View/Download:2/0  |  Submit date:2020/10/21
CDK8  transcriptional regulation  e2f1  apaf1  radiotherapy  apoptosis