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HFCAS OpenIR

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Darinaparsin (ZIO-101) enhances the sensitivity of small-cell lung cancer to PARP inhibitors 期刊论文
ACTA PHARMACOLOGICA SINICA, 2022
作者:  Cao, Guo-Zhen;  Ma, Li-Ying;  Zhang, Zong-Hui;  Wang, Xiao-Lin;  Hua, Jing-Han;  Zhang, Jia-Hui;  Lv, Yang;  Zhang, Shao-Bo;  Ou, Jian;  Lin, Wen-Chu
收藏  |  浏览/下载：43/0  |  提交时间：2022/12/22
small-cell lung cancer  H3  3  PARP1  PARP inhibitor  darinaparsin  combination treatment  
Olaparib maintenance monotherapy in Chinese patients with platinum-sensitive relapsed ovarian cancer: China cohort from the phase III SOLO2 trial 期刊论文
ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, 2022
作者:  Liu, Jihong;  Yin, Rutie;  Wu, Lingying;  Zhu, Jianqing;  Lou, Ge;  Wu, Xiaohua;  Zhou, Qi;  Gao, Yunong;  Kong, Beihua;  Lu, Xin;  Wang, Jing;  Chen, Youguo;  Cheng, Ying;  Wang, Yueling;  Lu, Weiguo;  Li, Wei;  Ma, Xin;  Hsu, Kate
收藏  |  浏览/下载：52/0  |  提交时间：2022/05/05
BRCA mutation  China  olaparib  ovarian cancer  PARP inhibitor  
Pamiparib Monotherapy for Patients with Germline BRCA1/2-Mutated Ovarian Cancer Previously Treated with at Least Two Lines of Chemotherapy: A Multicenter, Open-Label, Phase II Study 期刊论文
CLINICAL CANCER RESEARCH, 2022, 卷号: 28
作者:  Wu, Xiaohua;  Zhu, Jianqing;  Wang, Jing;  Lin, Zhongqiu;  Yin, Rutie;  Sun, Wei;  Zhou, Qi;  Zhang, Songling;  Wang, Danbo;  Shi, Hong;  Gao, Yunong;  Huang, Yi;  Li, Guiling;  Wang, Xiuli;  Cheng, Ying;  Lou, Ge;  Gao, Qinglei;  Wang, Li;  Du, Xiuping;  Pan, Mei;  Mu, Xiyan;  Li, Li;  Li, Miao;  Mu, Song;  Kong, Beihua
收藏  |  浏览/下载：73/0  |  提交时间：2022/03/28
An upward 9.4 T static magnetic field inhibits DNA synthesis and increases ROS-P53 to suppress lung cancer growth 期刊论文
TRANSLATIONAL ONCOLOGY, 2021
作者:  Yang, Xingxing;  Song, Chao;  Zhang, Lei;  Wang, Junjun;  Yu, Xin;  Yu, Biao;  Zablotskii, Vitalii;  Zhang, Xin
浏览  |  Adobe PDF(4320Kb)  |  收藏  |  浏览/下载：72/30  |  提交时间：2021/12/15
Correction to: The dual HDAC-PI3K inhibitor CUDC-907 displays single-agent activity and synergizes with PARP inhibitor olaparib in small cell lung cancer 期刊论文
Journal of Experimental & Clinical Cancer Research, 2021, 卷号: 40
作者:  Ma,Liying;  Bian,Xing;  Lin,Wenchu
收藏  |  浏览/下载：42/0  |  提交时间：2021/11/29
The dual HDAC-PI3K inhibitor CUDC-907 displays single-agent activity and synergizes with PARP inhibitor olaparib in small cell lung cancer 期刊论文
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2020, 卷号: 39
作者:  Ma, Liying;  Bian, Xing;  Lin, Wenchu
收藏  |  浏览/下载：81/0  |  提交时间：2020/11/30
SCLC  PI3K  HDAC  CUDC-907  PARP1  Olaparib  DSB repair  Combination treatment  
Terphenyllin Suppresses Orthotopic Pancreatic Tumor Growth and Prevents Metastasis in Mice 期刊论文
FRONTIERS IN PHARMACOLOGY, 2020, 卷号: 11
作者:  Zhang, Jia;  Wang, Weiyi;  Zhou, Yuan;  Yang, Jing;  Xu, Jingli;  Xu, Zhiyuan;  Xu, Beihua;  Yan, Li;  Cheng, Xiang-Dong;  Li, Minghua;  Qin, Jiang-Jiang
收藏  |  浏览/下载：49/0  |  提交时间：2020/11/26
terphenyllin  pancreatic cancer  metastasis  Bax  Bcl-2  Puma  
Discovery of 2-(4-Chloro-3-(trifluoromethyl)phenyl)-N-(4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)acetamide (CHMFL-KIT-64) as a Novel Orally Available Potent Inhibitor against Broad-Spectrum Mutants of 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019
作者:  Yun Wu;  Beilei Wang;  Junjie Wang;  Qi S(亓爽);  Fengming Zou;  Ziping Qi;  Feiyang Liu;  Wenchao Wang;  Qingsong Liu;  Jing Liu
浏览  |  Adobe PDF(5207Kb)  |  收藏  |  浏览/下载：124/63  |  提交时间：2020/10/20
Discovery of N-(4-(6-Acetamidopyrimidin-4-yloxy)phenyl)-2-(2-(trifluoromethyl)phenyl)acetamide (CHMFL-FLT3-335) as a Potent FMS-like Tyrosine Kinase 3 Internal Tandem Duplication (FLT3-ITD) Mutant Selective Inhibitor for Acute Myeloid Leukemia 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 2, 页码: 875-892
作者:  Liang, Xiaofei;  Wang, Beilei;  Chen, Cheng;  Wang, Aoli;  Hu, Chen;  Zou, Fengming;  Yu, Kailin;  Liu, Qingwang;  Li, Feng;  Hu, Zhenquan;  Lu, Tingting;  Wang, Junjie;  Wang, Li;  Weisberg, Ellen L.;  Li, Lili;  Xia, Ruixiang;  Wang, Wenchao;  Ren, Tao;  Ge, Jian;  Liu, Jing;  Liu, Qinsong
浏览  |  Adobe PDF(13868Kb)  |  收藏  |  浏览/下载：368/319  |  提交时间：2020/05/21
Sodium chloride (NaCl) potentiates digoxin-induced anti-tumor activity in small cell lung cancer 期刊论文
CANCER BIOLOGY & THERAPY, 2019, 卷号: 20, 期号: 1, 页码: 52-64
作者:  Deng, Ke;  Shen, Jiawei;  Wang, Wei;  Li, Ming;  Li, Hong;  Chen, Cheng;  Zhao, Huan;  Zhang, Mei;  Xue, Tian;  Liu, Qingsong;  Lui, Vivian Wai Yan;  Hong, Bo;  Lin, Wenchu
浏览  |  Adobe PDF(3554Kb)  |  收藏  |  浏览/下载：67/27  |  提交时间：2020/03/31
small cell lung cancer  digoxin  NaCl  cardiac glycosides  ATP1A1