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S3I-201 derivative incorporating naphthoquinone unit as effective STAT3 inhibitors: Design, synthesis and anti-gastric cancer evaluation 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2022, 卷号: 71
作者:  Li, Haobin;  Cai, Maohua;  Cao, Fei;  Yu, Dehua;  Yang, Jing;  Yu, Wenkai;  Chu, Chu;  Guan, Xiaoqing;  Qin, Jiang-Jiang;  Dong, Jinyun
收藏  |  浏览/下载：40/0  |  提交时间：2022/12/22
STAT3 inhibitor  Quinone derivative  S3I-201  Anti -gastric cancer drug  
Safety and Efficacy of D-1553 in Patients with KRAS G12C Mutated Non-Small Cell Lung Cancer: A Phase 1 Trial 期刊论文
JOURNAL OF THORACIC ONCOLOGY, 2022, 卷号: 17
作者:  Lu, S.;  Jian, H.;  Zhang, Y.;  Song, Z.;  Zhao, Y.;  Wang, P.;  Jiang, L.;  Gong, Y.;  Zhou, J.;  Dong, X.;  Yang, N.;  Fang, J.;  Zhuang, W.;  Cang, S.;  Ma, R.;  Shi, J.;  Wu, P.;  Lu, J.;  Xiang, Z.;  Shi, Z.;  Zhang, L.;  Wang, Y.
收藏  |  浏览/下载：56/0  |  提交时间：2022/12/23
Non-small cell lung cancer  KRAS G12C mutation  Small molecular inhibitor  
CircVAPA promotes small cell lung cancer progression by modulating the miR-377-3p and miR-494-3p/IGF1R/AKT axis 期刊论文
Molecular Cancer, 2022, 卷号: 21
作者:  Hua,Jinghan;  Wang,Xiaolin;  Ma,Liying;  Li,Jingxin;  Cao,Guozhen;  Zhang,Shaobo;  Lin,Wenchu
收藏  |  浏览/下载：38/0  |  提交时间：2022/12/22
CircVAPA  SCLC  Progression  miR-377-3p  miR-494-3p  IGF1R  AKT  BMS-536924  
Systemic Therapy for Hepatocellular Carcinoma: Chinese Consensus-Based Interdisciplinary Expert Statements 期刊论文
LIVER CANCER, 2022, 卷号: 11
作者:  Sun, Yongkun;  Zhang, Wen;  Bi, Xinyu;  Yang, Zhengqiang;  Tang, Yu;  Jiang, Liming;  Bi, Feng;  Chen, Minshan;  Cheng, Shuqun;  Chi, Yihebali;  Han, Yue;  Huang, Jing;  Huang, Zhen;  Ji, Yuan;  Jia, Liqun;  Jiang, Zhichao;  Jin, Jing;  Jin, Zhengyu;  Li, Xiao;  Li, Zhiyu;  Liang, Jun;  Liu, Lianxin;  Liu, Yunpeng;  Lu, Yinying;  Lu, Shichun;  Meng, Qinghua;  Niu, Zuoxing;  Pan, Hongming;  Qin, Shukui;  Qu, Wang;  Shao, Guoliang;  Shen, Feng;  Song, Tianqiang;  Song, Yan;  Tao, Kaishan;  Tian, Aiping;  Wang, Jianhua;  Wang, Wenling;  Wang, Zhe;  Wu, Liqun;  Xia, Feng;  Xing, Baocai;  Xu, Jianming;  Xue, Huadan;  Yan, Dong;  Yang, Lin;  Ying, Jianming;  Yun, Jingping;  Zeng, Zhaochong;  Zhang, Xuewen;  Zhang, Yanqiao;  Zhang, Yefan;  Zhao, Jianjun;  Zhou, Jianguo;  Zhu, Xu;  Zou, Yinghua;  Dong, Jiahong;  Fan, Jia;  Lau, Wan Yee;  Sun, Yan;  Yu, Jinming;  Zhao, Hong;  Zhou, Aiping;  Cai, Jianqiang
收藏  |  浏览/下载：36/0  |  提交时间：2022/12/23
Chinese interdisciplinary experts  Hepatocellular carcinoma  Molecular targeted therapy  Consensus  
BRD4 Targets the KEAP1-Nrf2-G6PD Axis and Suppresses Redox Metabolism in Small Cell Lung Cancer 期刊论文
ANTIOXIDANTS, 2022, 卷号: 11
作者:  Lv, Yang;  Lv, Xiaotong;  Zhang, Jiahui;  Cao, Guozhen;  Xu, Changzhi;  Zhang, Buchang;  Lin, Wenchu
收藏  |  浏览/下载：46/0  |  提交时间：2022/05/16
small cell lung cancer  BRD4  KEAP1  Nrf2  pentose phosphate pathway  
Super-enhancer-associated TMEM44-AS1 aggravated glioma progression by forming a positive feedback loop with Myc 期刊论文
Journal of Experimental & Clinical Cancer Research, 2021, 卷号: 40
作者:  Bian,Erbao;  Chen,Xueran;  Cheng,Li;  Cheng,Meng;  Chen,Zhigang;  Yue,Xiaoyu;  Zhang,Zhengwei;  Chen,Jie;  Sun,Libo;  Huang,Kebing;  Huang,Cheng;  Fang,Zhiyou;  Zhao,Bing;  Li,Jun
收藏  |  浏览/下载：53/0  |  提交时间：2021/11/15
Glioma  lncRNA  TMEM44-AS1  Super-enhancer  Myc  
EXT1 methylation promotes proliferation and migration and predicts the clinical outcome of non-small cell lung carcinoma via WNT signalling pathway 期刊论文
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2021, 卷号: 25
作者:  Kong, Wencui;  Chen, Ying;  Zhao, Zhongquan;  Zhang, Lei;  Lin, Xiandong;  Luo, Xingguang;  Wang, Shuiliang;  Song, Zhengbo;  Lin, Xiangwu;  Lai, Guoxiang;  Yu, Zongyang
收藏  |  浏览/下载：49/0  |  提交时间：2021/04/26
DNA methylation  EXT1  migration  prognosis  proliferation  WNT  
The deep learning model combining CT image and clinicopathological information for predicting ALK fusion status and response to ALK-TKI therapy in non-small cell lung cancer patients 期刊论文
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2020
作者:  Song, Zhengbo;  Liu, Tianchi;  Shi, Lei;  Yu, Zongyang;  Shen, Qing;  Xu, Mengdi;  Huang, Zhangzhou;  Cai, Zhijian;  Wang, Wenxian;  Xu, Chunwei;  Sun, Jingjing;  Chen, Ming
收藏  |  浏览/下载：37/0  |  提交时间：2020/10/26
Deep learning model  Anaplastic lymphoma kinase  Computed tomography  Non-small cell lung cancer  
Osimertinib successfully combats EGFR-negative glioblastoma cells by inhibiting the MAPK pathway 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020
作者:  Chen, Cheng;  Cheng, Chuan-dong;  Wu, Hong;  Wang, Zuo-wei;  Wang, Li;  Jiang, Zong-ru;  Wang, Ao-li;  Hu, Chen;  Dong, Yong-fei;  Niu, Wan-xiang;  Qi, Shuang;  Qi, Zi-ping;  Liu, Jing;  Wang, Wen-chao;  Niu, Chao-shi;  Liu, Qing-song
浏览  |  Adobe PDF(3476Kb)  |  收藏  |  浏览/下载：95/35  |  提交时间：2020/11/26
glioblastoma  osimertinib  temozolamide  MAPK-signaling pathway  MNK  eukaryotic translation initiation factor 4E  
A Novel Microfluidic Device Integrated with Chitosan-Modified Capillaries for Rapid ZIKV Detection 期刊论文
Micromachines, 2020, 卷号: 11
作者:  朱灵( zhu ling)
浏览  |  Adobe PDF(3906Kb)  |  收藏  |  浏览/下载：192/44  |  提交时间：2020/11/19
in situ PCR  molecular diagnosis  microfluidic chip  POC device  ZIKV